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Postimplantation development of cloned rabbit embryos reconstructed with foetal and adult skin-derived fibroblast cell nuclei

100%

Kosenyuk Y. , Skrzyszowska M. , Gajda B. , Rynska B.

Annals of Animal Science

2012

tom 12

nr 1

Double transgenic pigs with combined expression of human alpha1,2-fucosyltransferase and alpha-galactosidase designed to avoid hyperacute xenograft rejection

100%

Zeyland J. , Wozniak A. , Gawronska B. , Juzwa W. , Jura J. , Nowak A. , Slomski R. , Smorag Z. , Szalata M. , Mazurek U. , Lipinski D.

Archivum Immunologiae et Therapiae Experimentalis

2014

tom 62

nr 5

The effect of fucoidan, a potential new, natural, anti-neoplastic agent on uterine sarcomas and carcinosarcoma cell lines: ENITEC collaborative study

80%

Bobinski M. , Okla K. , Bednarek W. , Wawruszak A. , Dmoszynska-Graniczka M. , Garcia-Sanz P. , Wertel I. , Kotarski J.

Archivum Immunologiae et Therapiae Experimentalis

2019

tom 67

nr 2

Involvement of cytoskeleton in orientation of cell division in contact guided cells

80%

Krzysiek-Maczka G. , Michalik M. , Madeja Z. , Korohoda W.

Folia Biologica

2010

tom 58

nr 1-2

21-27

Loop formation by the transgene WAP:6xHishGH in transgenic rabbit fibroblasts, revealed by fluorescence in situ hybridization to nuclear halos

80%

Michalak E. , Lipinski D. , Slomski R.

Journal of Applied Genetics

2006

tom 47

nr 3

Using fluorescence in situ hybridization (FISH) to somatic nuclear halos from transgenic rabbits WAP:6xHishGH, we present evidence for stability of transgenesis at the chromatin level. FISH performed on fibroblasts from a homozygous individual showed 2 independent loops from both chromosomes of pair 7. On a heterozygous individual, FISH detected a single loop. According to the concept of chromatin loops and their influence on gene expression, this shows that the human growth hormone transgene, which was actively expressed in mammary gland under the influence of the tissue-specific promoter, was inactive in examined skin fibroblasts.