Ten serwis zostanie wyłączony 2025-02-11.
Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl
Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 5

Liczba wyników na stronie
first rewind previous Strona / 1 next fast forward last
Wyniki wyszukiwania
Wyszukiwano:
w słowach kluczowych:  rzesistek
help Sortuj według:

help Ogranicz wyniki do:
first rewind previous Strona / 1 next fast forward last
EN
The objective of the study was to ascertain the presence of complement binding antibodies against T. vaginalis, T. tenax and hominis in the blood of women with chronic simultaneous (two species) trichomoniasis, and a comparison of the dynamics of antibody formation in the blood of women with one species trichomoniasis. The determinations were made prior to and following the treatment with Fasigyn, in hope to obtain additional data on antigene properties of trichomonas parasites of human organism. The test for complement binding was made for 144 women, 84 of them simultaneously infected with two of the three species of Trichomonas mentioned above and 60 with one. It has been found that in the former the complement binding antibodies attain higher concentrations (except antibodies against T. hominis), and following the Fasigyn treatment in all the cases they return to the normal level later than in respective monospecific trichomoniasis. The highest concentrations of the antibodies, both against T. vaginalis and T. tenax have been found in women with simultaneous trichomoniasis of urogenital system and oral cavity. Lower concentrations of the antibodies against both these species of Trichomonas have been found in women with simultaneous trichomoniasis of both urogenital system and intestine or both intestine and oral cavity. This can be accounted for by a dose antigene relationship between T. vaginalis and T. tenax, and a much more distant relationship of both these species on the one hand and T. hominis on the other.
EN
By the modification of chemical structure of some drugs the series of ether compounds with potential anti-trichomoniasis and anti-fungial action were received.
EN
Trichomonacidal activity in vitro of 2 newly synthesized derivatives of benzoizothiazolinon (BIT) in comparison with metronidazole was determined by calculating lethal concentration for 50% trichomonal population (C₅₀). Experiments were carried out on 2 strains of T. vaginalis and 2 strains of T. anseris. Both preparations showed considerably higher trichomonacidal activity than metronidazole. Mean values of trichomonacidal activity of N-morpholinomethyl-1,2-benzoizothiazolinon-3 for T. vaginalis and T. anseris amounted to 885 and 1997 respectively, and were 6 and 8 times higher than those of hydrochloride of N-piperydynomethyloamide of (5-chlor-1,2-benzoizothiazolinon-3ylo-2)-acetic acid. The lowest trichomonacidal activity of hydrochloride of N-piperydynomethylamide of (5-chlor-1,2-benzoizothiazolinon-3ylo-2)-acetic acid was 10-fold higher than that of N-morpholinomethyl-1,2-benzoizothiazolinon-3 and several hundred times lower than metronidazole concentration.
first rewind previous Strona / 1 next fast forward last
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.