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Wplyw wysokich dawek witminy C i ozonu na przebieg stresu oksydacyjnego u szczurow

100%

Jedlinska-Krakowska M.

nr 10

1183-1185

The aim of the study was to determine whether high doses of Vitamin C may alleviate the effects of oxidative stress caused by ozone, or whether they actually intensify its course and demonstrate pro-oxidative activity. The experiment was conducted on adult male rats divided into 6 groups: Group I - control animals; Group II and III - animals which were simultaneously ozonated and administered intramuscular injections of Vit C in doses of 20 and 40 mg/rat respectively; Group IV and V - non-ozonated animals, which were administered the above doses of Vit C every fifth day for a period of 35 days; Group VI - rats ozonated without Vit C. The results of the study indicated that the highest level of indexes defining the intensity of oxidative stress occurred both in animals which were ozonated and given high doses of Vit C as well as in non-ozonated animals which were given high doses the vitamin. AST activity and glucose levels were also highest in the above groups and displayed a similar pattern. It may thus be assumed that high doses of Vit C do not prevent organisms from ozone-induced oxidative stress, and may even increase its intensity

Przebieg stresu oksydacyjnego w wybranych grupach sportowcow w trakcie wysilkow o roznej intensywnosci

44%

Nazarewicz R. , Babicz-Zielinska E.

nr Supl.

65-68

Celem pracy była ocena różnic w poziomie stresu oksydacyjnego w trakcie wysiłku tlenowego i beztlenowego. Przeprowadzono badania na grupach chłopców trenujących dyscypliny o różnym charakterze pracy. Do oceny poziomu stresu oksydacyjnego posłużono się markerem stresu, jakim jest kwas moczowy. Oceniono również wielkość spożycia białka.

The aim of this study has been to investigate the influence of aerobic and anaerobic exercise on oxidative stress. The research was undertaken over a group of 61 young people of different physical activity (age group 15-18 years). The control group included sedentary persons. In the sportsmen group the amounts of uric acid (UA) and urea excreted in urine and body weight were measured in two series before and after training camp. In sedentary group there was only one series. Protein intake was assesed using urea excrection. In the control group the amounts of uric acid reached 60 µmol/kg m.c; in the aerobic exercise group 45.46 µmol/kg before the camp and 55.29 µmol/kg after; adequately 70.2 µmol/kg and 62.51 µmol/kg in the anaerobic exercise group. Protein intake frequently was different in comparison to required. The study shows high correlation between protein intake and uric acid excretion in all groups. The high protein intake seems to decrease participation of uric acid in anyoxidative deffence.