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EN
New Zealand white rabbits were given cypermethrin by gastric intubation at the rate of 0, 300, 600 and 1000 mg per 1 kg on the 4th, 10th, 13th and 18th day of their pregnancies. The fetuses were aborted on day 28. AH 166 fetuses were examined for external, internal and skeletal malformations or variations. There was no evidence of teratogenic action of cypermethrin in the rabbits; however, embryotoxic effects were detected. The results may have some value for prenatal toxicology of other mammal species and humans poisoned by cypermethrin, and of some benefit for the ecotoxicology of hares in the area where this pesticide is applied as a plant protection agent.
EN
Pregnant gilts (in the first month of pregnancy) were infected intranasally with SIV H1N2. Clinical signs, presence of SIV RNA in nasal swabs, haemagglutination titer, hematological parameters, concentrations of interleukin (IL-10, IFNγ) and acute phase proteins (APP) (CRP, Hp), as well as production parameters, were evaluated. The concentrations of APP and cytokines were analyzed with the use of ELISA assays. Antibodies against SIV were detected with the haemagglutination inhibition assay, and the presence of RNA with RT-PCR. No clinical sings typical of swine influenza were found in the infected gilts. The gilts did not show any signs of pregnancy pathology, and no abortions were observed. No significant differences were found between the infected and control gilts with regard to the number of piglets born, hematological parameters, or the concentrations of APP and cytokines. The presence of specific antibodies against SIV was confirmed in the infected gilts starting from 14 dpi. The presence of SIV RNA in nasal swabs collected from the gilts was confirmed within 4 dpi. No SIV RNA were found in samples taken from newborn piglets.
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