Over the years since ancient through contemporary times, rinderpest has been a lethal threat to cloven-hoofed animals, especially cattle. In this review, the most particular facts connected with the occurrence and eradication of this mortal plague of animals were presented. The history of the struggle against rinderpest is closely bound with the foundation of the first veterinary school, as well as the World Organization for Animal Health (OIE). The FAO/OIE declaration of rinderpest global eradication is expected to be announced in the near future.
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