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Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

100%

Baczyńska-Strzecha M. , Kalinka J.

International Journal of Occupational Medicine and Environmental Health

2017

tom 30

nr 6

933-941

Objectives Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. Material and Methods 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. Results Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094). Conclusions Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933–941

Early diagnosis of threatened premature labor by electrohysterographic recordings – The use of digital signal processing

84%

Lemancewicz A. , Borowska M. , Kuć P. , Jasińska E. , Laudański P. , Laudański T. , Oczeretko E.

Biocybernetics and Biomedical Engineering

2016

tom Vol. 36, no. 1

302--307

Prevention and early diagnosis of imminent preterm labor are considered to be the most important perinatal challenge nowadays. Significant progress has been observed on postnatal care of premature infants, but without reducing the prevalence of preterm delivery. Our study was focused on comparison of three methods of spectral analysis of electro-hysterographic (EHG) signals: fast Fourier transform (FFT), wavelet transform (WT) and autoregressive modeling (AR). Complexity of the electrohysterographic signals was analyzed by using: the approximate entropy (ApEn), Lempel–Ziv complexity measure (L–Z). Additionally, the work evaluated the applicability of EHG in diagnosing imminent premature labor. EHG signals were recorded among 60 patients with threatened preterm labor symptoms between the 24th and 34th week of pregnancy. Patients included to the study had a shortened cervix (less than 20 mm) without regular uterine contractions recorded on regular cardiotocography (CTG). The women were divided into two groups: those delivering within 7 days – group A (n = 15) and women delivering after 7 days – group B (n = 45). The study confirmed differences in bioelectrical activity of uterus between patients delivering prematurely within 7 days and after from the EHG registration for all analyzed methods.