The purpose of studies was to elaborate and estimate the usefulness of a new preparation for treatment of metritis. The Metrisan AN was made out in the National Veterinary Research Institute on the basis of the experiences of the first author. The preparation contains the neomycin, ampicyllin as free and bound form, and components intensifying phagocytosis. The investigations were carried out on the total of 406 cows with clinical symptoms of ichoroid, purulent and muco-purulent form of metritis. It was found that one intrauterine infusion of one dose of Metrisan AN causes recovery of the endometritis III and II degree. Two doses of the Metrisan AN as first treatment and one dose given intrauterine on 7th day leads to recoveries of the ichoroid or purulent puerperal metritis. The cows which became healthy as a result of treatment with Metrisan AN had good indicators of fertility: pregnancy index, conception interval, conception after first insemination, index of insemination, and culling rate. It was also found that treatment with one dose of Metrisan AN requires no withdrawal time for milk.
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