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Prenylation of RAB 3A protein in vitro

100%

Szymanska M. , Swiezewska E.

Cellular and Molecular Biology Letters

1997

tom 02

nr 2

Ras protein of the slime mold Physarum polycephalum is farnesylated in vitro

86%

Talarczyk E. , Hung V. S. , Kozlowski P. , Trzcinska-Danielewicz J. , Swiezewska E.

Acta Biochimica Polonica

1999

tom 46

nr 3

Physarum Ppras1 protein was efficiently prenylated by prenyltransferases of spinach. Surprisingly in spite of the C-terminal sequence (CLLL) specific for geranylgeranylation the protein was preferentially farnesylated. Consequences of this observation are discussed.

Prenyl sulfates as alkylating reagents for mercapto amino acids

72%

Maltsev S. , Sizova O. , Utkina N. , Shibaev V. , Chojnacki T. , Jankowski W. , Swiezewska E.

Acta Biochimica Polonica

2008

tom 55

nr 4

807-813

A new methodology for prenylation of thiol compounds has been developed. The approach is based on the use of prenyl sulfates as new reagents for S-prenylation of benzenethiol and cysteamine in aqueous systems. The C10-prenols geraniol and nerol that differ in the configuration (E or Z, correspondingly) of the α-isoprene unit were efficiently O-sulfated in the presence of a pyridine-SO3,complex. The obtained geranyl and neryl sulfates were tested as alkylating agents. These compounds were chosen to reveal the influence of the α-isoprene unit configuration on their alkylation (prenylation) ability. S-Geranyl cysteine was prepared to demonstrate the applicability of this method for prenylation of peptides containing mercapto amino acids.

Isolation of a cDNA encoding the alpha-subunit of CaaX-prenyltransferases from Catharanthus roseus and the expression of the active recombinant protein farnesyltransferase

72%

Courdavault V. , Burlat V. , St-Pierre B. , Gantet P. , Giglioli-Guivarc'h N.

Cellular and Molecular Biology Letters

2005

tom 10

nr 4

New approaches to the prevention and treatment of viral diseases

58%

Pronin A. V. , Narovlyansky A. N. , Sanin A. V.

Archivum Immunologiae et Therapiae Experimentalis

2021

tom 69

nr 1