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EN
Objective: The aim of this study was to evaluate cases of of ear, nose and pharyngeal (ENT) foreign body (FB) in pediatric patients referred to the pediatric emergency department of the Department of Otorhinolaryngology in Tokat State Hospital (Turkey). Methods: The paper comprises a retrospective study of all ENT foreign bodies presented to the pediatric emergency Department of Otorhinolaryngology in Tokat State Hospital (Turkey) between January 1, 2012 and December 31, 2018. Subject to evaluation were also demographic and clinical characteristics of the patients, types and anatomic locations of FBs, locations of FB by age groups, the method used to remove FBs and the distribution of FB cases by months. Results: A total of 829 FB cases were evaluated in this study. The mean age of patients was 47.8 ± 31.4 months. Of all patients, 404 (48.5%) were male, and 425 (51.2%) were female. The nose (58.7%) and the ear (20.2%) were the most common anatomical locations followed by mouth/pharynx/tonsil (12.3%), esophagus (6.2%) and the laryngotracheobronchial tree (2.4%). The most common FBs in different locations were beads in the nose (30.8%), beads in the ear (32.1%), fishbones in the mouth/pharynx/tonsil (56.8%), nuts and peanuts in laryngotracheobronchial tree (70%) and a coin/disc battery in the esophagus (80.7%). Conclusion: FB in ENT is among the emergency conditions that require different diagnostic and treatment approaches based on anatomic localizations. Proper vision, adequate equipment and immobilization are important in the removal of ENT foreign bodies in children.
EN
The paper presents the rare case of lipoma of parapharyngeal space and oropharynx in 46-year-old man who came out suddenly while eating, giving the feeling of an obstacle in the throat. Preoperative diagnosis was based on a characteristic image of KT (low density, presence of capsule, lack of contrast gain and the use of fat suppression technique). The tumor was surgically removed in its entirety, from reaching the mouth. Emphasized the rarity of tumors of the weaving within the parapharyngeal space and throat, conditioned by a small amount of fat in this area, as well as the possibility of turbulent obstructive symptoms caused by the sudden disclosure of a tumor located deep in the tissues.
EN
Objective: The aim of this study was to evaluate cases of of ear, nose and pharyngeal (ENT) foreign body (FB) in pediatric patients referred to the pediatric emergency department of the Department of Otorhinolaryngology in Tokat State Hospital (Turkey). Methods: The paper comprises a retrospective study of all ENT foreign bodies presented to the pediatric emergency Department of Otorhinolaryngology in Tokat State Hospital (Turkey) between January 1, 2012 and December 31, 2018. Subject to evaluation were also demographic and clinical characteristics of the patients, types and anatomic locations of FBs, locations of FB by age groups, the method used to remove FBs and the distribution of FB cases by months. Results: A total of 829 FB cases were evaluated in this study. The mean age of patients was 47.8 ± 31.4 months. Of all patients, 404 (48.5%) were male, and 425 (51.2%) were female. The nose (58.7%) and the ear (20.2%) were the most common anatomical locations followed by mouth/pharynx/tonsil (12.3%), esophagus (6.2%) and the laryngotracheobronchial tree (2.4%). The most common FBs in different locations were beads in the nose (30.8%), beads in the ear (32.1%), fishbones in the mouth/pharynx/tonsil (56.8%), nuts and peanuts in laryngotracheobronchial tree (70%) and a coin/disc battery in the esophagus (80.7%). Conclusion: FB in ENT is among the emergency conditions that require different diagnostic and treatment approaches based on anatomic localizations. Proper vision, adequate equipment and immobilization are important in the removal of ENT foreign bodies in children.
EN
The organisation of the neuromuscular system in cercariae, metacercariae and adult Opisthorchis felineus was studied. The patterns of nerves immunoreactive (IR) to antibodies towards serotonin (5-HT) and FMRFamide are described in relation to the musculature, stained with TRITC-conjugated phalloidin. The general organisation of the musculature in the body wall, suckers, pharynx, intestine and sphincter of the excretory pore remains the same from the larval stages to the adult worms. However, the diameter of the individual muscle fibres increases distinctly in the adult worms. The general pattern of 5-HT IR fibres in cercariae, metacercariae and adult O. felineus remains the same. Despite the large increase in body size, the number of 5-HT IR neurones remains almost the same in the cercariae and metacercariae and only a modest increase in number of neurones was observed in the adult worms. Thus the proportion of 5-HT IR neurones/body mass is greatest in the actively moving cercariae. Anti-FMRFamide stains the nervous system strongly.
EN
A new bucephalid species, Prosorhynchoides carvajali sp. nov. is described. This parasite was found in three marine fish, Auchenionchus microcirrhis (type-host), A. variolosus and Sicyases sanguineus (other-hosts), collected from the intertidal rocky zones of central Chile. P. carvajali sp. nov. is characterized by a pharynx in a post-equatorial position, a large cirrus sac length (half of the total worm length) and rounded caecum extending dorsally and anteriorly from pharynx. Although Prosorhynchoides carvajali sp. nov. closely resembles P. labiata; the latter has an elongated, narrow and inverted-U-shape caecum, contrasting to P. carvajali sp. nov. which has a larger rounded caecum, directed anteriorly. To our knowledge this is the first known report of Prosorhynchoides on the South American Pacific coast.
EN
Radio- and chemotherapy for malignant neoplasms, especially in head and neck region, is associated with a greater risk of fungal infections due to secondary alterations in the mucous membranes. The study had three aims: 1. to determine the signs and symptoms which occur among patients undergoing radiotherapy; 2. to determine the fungi prevalence in the mouth and throat of patients before, during and after radiotherapy; 3. to examine the sensitivity of strains to antimycotic drugs. The study comprised 44 patients (11 female, 33 male) with head and neck cancers, examined at the following stages: before radiotherapy (44 patients – batch 1), 3rd week of therapy (30 of the 44 patients – batch 2), last day of therapy (28 of batch 2 – batch 3) and the 6th week after completion of radiotherapy (10 of batch 3 – batch 4). Clinical examination was performed and mycological status was estimated from an oral rinse on a selected medium. The fungal strains were isolated and sensitivity to antifungal drugs was determined. The most common symptoms were pain, dysphagia, and dysgeusia. Physical examination revealed signs of mucositis mainly among patients from batches 2 and 3. The presence of fungi in the mouth and throat was noted in over 2/3 (66.2%) of the patients from batch 1, and in 4/5 (80%) of batch 2. The fungi were detected in over half (57.1%) of patients from batch 3 and also in patients from batch 4. In all cases, fungi of various Candida species were identified: 6 species in batch 1, 8 in batch 2, 6 in batch 3 and 5 in batch 4. The most frequently detected species was C. albicans, constituting 40–60%; the other species detected are known to be resistant to antimycotic drugs. The isolated strains were the most sensitive to nystatin and miconazole, and the least to ketoconazole and fluconazole. Conclusions: 1. Patients undergoing radiotherapy complain of pain, dysphagia, and dysgeusia; in most cases mucositis is diagnosed. 2. The high prevalence of fungi in the mouth and throat of patients treated by radiotherapy reinforces the need to perform mycological examinations in this group of patients to detect fungi, identify their species and determine of their sensitivity to drugs in order to prevent complications. 3. The species most frequently isolated from the patients are C. albicans and C. glabrata. The latter is characterized by resistance to the majority of antimycotic medications. 4. Most of the isolated strains are sensitive to nystatin and miconazole (applied locally) and to itraconazole (absorbed from the gastrointestinal tract).
PL
Celem badań bylo sprawdzenie występowania zmian histopatologicznych w narządach wewnętrznych, określenie ich rodzaju i czasu utrzymywania się u nie szczepionych oraz szczepionych przeciw chorobie Aujeszkyego (chA) starszych świń po zakażeniu zjadliwym wirusem chA. Badania przeprowadzono na 18 serologicznie ujemnych w kierunku chA warchlakach rasy wbp w wieku 12 tyg., które podzielono na 3 grupy: T - szczepione TK- i gX-ujemną szczepionką delecyjną TOLVID (Upjohn-USA); S - szczepione atenuowaną szczepionką Suivac A (Biowet-Puławy) i K - nie szczepione (kontrolna). Po 3 mies. świnie zakażono donosowo 105-5 TCIDg0/ml zjadliwego szczepu NIA-3 wirusa chA, wkraplając po 1 ml zawie­siny wirusa w każde nozdrze. Od świń padłych lub uśpionych w 5., 8. i 23. dniu po zakażeniu pobierano do badań histopatologicznych wycinki różnych narządów: węzłów chłonnych podżuchwowych i przy- uszniczych, migdałków, śledziony, tchawicy, płuc, gardła, przełyku, dwunastnicy, wątroby, nerki, skóry z miejsca iniekcji szczepionki. Omówiono i częściowo zilustrowano stwierdzone zmiany histopatologiczne zwracając uwagę na ich różnorodność w przebiegu zakażenia wirusem chA, mniejsze natężenie u świń szczepionych, ale o wiele dłuższy okres ich utrzymywania się niż pozakaźnej reakcji klinicznej, co z powodu okresowego zahamowania wzrostu może być przyczyną znacznych strat gospodarczych.
EN
Research was aimed at determining histopathological changes - their type and duration - in inner organs of pigs, vaccinated and non vaccinated against Aujeszky's disease (AD), ; after infection with its virulent virus (ADV). Studies concerned 18 piglets of Polish Large White breed, at the age of 12 weeks, serologically negative to AD. They were divided into 3 groups: group T - vaccinated with deleted, TK- and gX-negative TOLVID vaccine (Upjohn - USA), group S - vaccinated with attenuated Suivac A vaccine (Biowet - Puławy) i and control group K - not vaccinated. After 3 months, piglets were infected with 105.5 TCID50/ml of NIA-3 virulent strain of ADV: 1 ml of its suspension was instilled into each nostril of a piglet. On 5th, 8th and 23rd day post infection (d.p.i.), some segments of inner organs of dead or anaesthetized animals, such as submandibular lymphnodi, tonsils, spleen, trachea, lungs, pharynx, esophagus, duodenum, liver, kidneys, and skin out of injection i place, were analyzed. Histopathological changes that were found are described and partly exemplified in the paper. Special emphasis is laid on their lower intensity in case of vaccinated pigs and on their duration which turned out to be much longer than that after clinical infection and which affected piglets' growth in a negative way, leading to certain economic losses.
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