Wyniki wyszukiwania - Biblioteka Nauki

1

Influence of bilateral ovariectomy on the morphology and ultrastructure of the pineal gland in the pig [Sus scrofa] - quantitative and qualitative study

100%

Wyrzykowski Z. , Przybylska B. , Wyrzykowska K. , Kaleczyc J.

Folia Morphologica

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1992

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tom 51

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nr 2

2

Influence of gonadectomy on serum fT4 concentrations in male and female dogs

86%

Krzyzewska-Mlodawska A. , Max A. , Bartyzel B. J.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2014

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tom 17

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nr 1

3

Effect of treadmill exercise on lumbar vertebrae in ovariectomized rats: anthropometrical and mechanical analyses

86%

Simoes P. A. , Zamarioli A. , Bloes P. , Mazzocato F. C. , Pereira L. H. A. , Volpon J. B. , Shimano A. C.

Acta of Bioengineering and Biomechanics

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2008

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tom Vol. 10, nr 2

39-41

EN

The purpose of this study was to examine the preventive effect of exercise on lumbar vertebrae in ovariectomized rats. Three-monthold female Wistar rats were divided into 3 groups: control group (A, n = 10); non-exercised ovariectomized group (B, n = 7) and exercised ovariectomized group (C, n = 7). The rats from group C were subjected to treadmill exercise (15 m/minute in the initial six weeks and 19 m/minute in the next six weeks, 1 hour/day, 4 days/week) for 12 weeks. At death, the fourth lumbar vertebrae were removed and an anthropometrical analysis by a paquimeter and a mechanical compression test by a universal test machine were performed. After 12 weeks, the ovariectomy decreased the superior–inferior vertebral height and the maximal braking load in group B compared to group A, while the exercise increased the vertebral mass in group C compared to both groups A and B ( p < 0.01) and the stiffness compared to group B. We concluded the physical activity has an important role to prevent the osteopenia in lumbar vertebrae.

4

Angiotensins II and IV modulate adrenocortical cell proliferation in ovariectomized rats

86%

Siejka A. , Melen-Mucha G. , Mucha S. A. , Pawlikowski M.

Journal of Physiology and Pharmacology

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2006

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tom 57

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nr 3

EN

Effects of angiotensins II (AngII), angiotensin IV (AngIV, 3-8 fragment of angiotensin II) and losartan (an antagonist of angiotensin receptor type 1) on the proliferation of adrenocortical cells in ovariectomized rats have been studied. The incorporation of bromodeoxyuridine (BrdU) into cell nuclei was used as an index of cell proliferation. AngIV decreased BrdU labeling index mainly in the reticularis zone and losartan (Los) was able to partially reverse this inhibitory effect of AngIV. AngII had no effect on the adrenocortical cell proliferation when given alone, however Los given simultaneously diminished BrdU incorporation into nuclei of glomerulosa and reticularis zones as compared with AngII. These findings suggest that AngII and AngIV modulate adrenocortical cell proliferation in ovariectomized rats.

5

Adropin, nesfatin-1 and angiotensin II receptor expression in the abdominal aorta in ovariectomized rats after nesfatin-1 treatment

72%

Pawlowska-Olszewska M. , Puzio I. , Tymicki G. , Kalisz G. , Sroka-Bartnicka A. , Blicharz-Kania A. , Nowakiewicz A. , Kosior-Korzecka U. , Kulak K.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 6

6

Modulation of anterior pituitary cell luteinizing hormone secretory activity by neuropeptide Y in early pregnant pigs

72%

Siawrys G. , Buchowski H.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 5

7

Melatonin from slow-release implants upregulates claudin-2 in the ovine choroid plexus

72%

Szczepkowska A. , Kowalewska M. , Skipor J.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 2

8

Gonadotropin-releasing hormone and kisspeptin-10 regulate nuclear receptor subfamily 5 group a member 1/catenin beta 1/nuclear receptor subfamily 0 group B member 1 activity in female rat anterior pituitary gland

72%

Zielinska-Gorska M. , Gorski K. , Biernacka K. , Sawosz E. , Kaminski T. , Gajewska A.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 3

9

Effect of intracerebroventricular infusion of genistein on prolactin and LH secretion in ovariectomized ewes during short days

72%

Romanowicz K. , Misztal T.

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tom 14

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nr 2

10

Complex estrogenic regulation of catechol-O-methyltransferase (COMT) in rats

58%

Schendzielorz N. , Rysa A. , Reenila I. , Raasmaja A. , Mannisto P. T.

Journal of Physiology and Pharmacology

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2011

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tom 62

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nr 4

11

Role of interleukin-6 on RANKL-RANK/osteoprotegerin system in hypothyroid ovariectomized mice

58%

Mysliwiec J. , Zbucki R. , Nikolajuk A. , Mysliwiec P. , Taranta A. , Kaminski K. , Bondyra Z. , Dadan J. , Gorska M. , Winnicka M.

Folia Histochemica et Cytobiologica

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2010

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tom 48

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nr 4

12

Effects of ovariectomy in prepubertal goats

58%

Dessauge F. , Finot L. , Wiart S. , Aubry J. M. , Ellis S. E.

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nr 3

127-133

13

Effects of sodium fluoride on bone metabolism and structural changes of the mandible in ovariectomized rats

58%

Bohatyrewicz A. , Wiechowska M. , Machoy-Mokrzyńska A. , Jurewicz A. , Leźnicka K. , Grocholewicz K. , Karaczun M. , Weyna E.

Problemy Nauk Stosowanych

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2018

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tom T. 8

137--146

EN

Introduction and aim: The role of fluorides in caries prevention is widely known, however, due to a large number of factors affecting the metabolism of bone tissue (e.g. estrogens), the evaluation of the effect of these compounds on the masticatory system requires comprehensive studies. The aim of the study was to examine the effect of fluorides on the chosen biochemical markers of bone remodelling, on the bone mass and structural changes in the lower jaw (mandible) of castrated rats, after six-week exposure to sodium fluoride in different doses. Material and methods: The experiment was conducted on an animal model using female Wistar rats divided into four groups: a control group and three research groups (ovariectomized and exposed to fluoride compounds in different doses in the drinking water). In order to evaluate the effect of estrogens shortage induced by double-sided ovariectomy and to analyze the fluorides influence on bone metabolism and structural changes of the mandible, tests of bone tissue metabolism markers, bone mineral content in the mandible, height of a molar tooth, height of alveolar appendix and index of rats' alveolar appendices heights were performed. Results: Ovariectomy procedure led to the appearance of higher concentrations of bone tissue resorption markers and lower mineral weight of mandible, but did not exert a considerable impact on mineral weight index in animals receiving fluorides. There was no statistical difference in the heights of molar teeth between all experimental groups. Conclusion: Eestrogens shortage, due to ovariectomy, reduces mineral weight of lower jaw bones and mineral weight index, and the fluoride supply prevents the loss of minerals from an osseous tissue.

PL

Wstęp i cel pracy: Rola fluorków w profilaktyce próchnicy jest powszechnie znana, jednakże ze względu na dużą liczbę czynników wpływających na metabolizm tkanki kostnej (np. estrogeny), ocena wpływu tych związków na układ żucia wymaga kompleksowych badań. Celem tego badania było zbadanie wpływu fluorków na wybrane markery przebudowy kości, na masę kości i strukturalne zmiany w dolnej szczęce (żuchwie) kastrowanych szczurów po sześciotygodniowej ekspozycji na różne dawki fluorku sodu. Materiał i metody: Doświadczenie przeprowadzono na modelu zwierzęcym, w którym samice szczurów Wistar podzielono na cztery grupy: grupę kontrolną i trzy grupy badawcze (poddane owariektomii i eksponowane różne dawki związków fluoru podawanych w wodzie pitnej). Aby ocenić wpływ niedoboru estrogenów wywołanego obustronną owariektomią i aby przeanalizować wpływ fluorków na metabolizm kostny i zmiany strukturalne żuchwy, konieczne było przeprowadzenie badań markerów metabolizmu kostnego oraz zawartości związków mineralnych w kości żuchwy, a także dokonanie pomiarów wysokości zęba trzonowego, wysokości wyrostka zębodołowego i wskaźnika wysokości wyrostków zębodołowych u badanych szczurów. Wyniki: Na skutek przeprowadzonej owariektomii zaobserwowano wyższe stężenia markerów resorpcji tkanki kostnej oraz niższą masę mineralną kości szczęki dolnej. Zabieg ten jednak nie miał znaczącego wpływu na wskaźnik masy mineralnej u zwierząt otrzymujących fluorki. Nie stwierdzono statystycznej różnicy w wysokości zębów trzonowych pomiędzy grupami eksperymentalnymi. Wnioski: Niedobór estrogenów spowodowany wycięciem jajników prowadzi do obniżenia masy mineralnej kości żuchwy oraz wskaźnika masy mineralnej, a fluorki zapobiegają utracie minerałów z tkanki kostnej.

14

Effect of ovariectomy on biochemical markers of bone turnover [ALP, ACP] and calcium content in rat mandible and teeth

58%

Rahnama M. , Swiatkowski W.

Bulletin of the Veterinary Institute in Puławy

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2002

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tom 46

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nr 2

15

Effect of estrogen replacement therapy on serum cytokines [Il-1alpha,Il-6, TNF-alpha] in overiectomized rats

58%

Rahnama M. , Tomaszewski T. , Swiatkowski W.

Bulletin of the Veterinary Institute in Puławy

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2002

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tom 46

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nr 2

16

Effects of different intensities of cold stress on certain physiological phenomena related to skeletal health in a hypogonadal rat model

58%

Islam M. N. , Chanda S. , Mitra C.

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tom 51

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nr 4,2

17

Female hormones act as natural antioxidants - a survey of our research

58%

Yagi K.

Acta Biochimica Polonica

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1997

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tom 44

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nr 4

EN

The increase in the lipid peroxide level in the serum and liver of female mice after bilateral ovariectomy evidenced antioxidant activities of female hormones. This increase was abolished upon administration of female hormones. Similar increase in the level of lipid peroxide was observed in the serum of women who had undergone bilateral ovariectomy. Injection of 2-hydroxyestradiol suppressed the increase in the lipid peroxide level in the liver of rats receiving whole-body gamma-ray irradiation. Considering that the mechanism of coronary atherosclerosis is ascribed at least in part to the increased level of lipid peroxides, estrogen therapy could be applied to women who had undergone bilateral ovariectomy prior to menopause or to normal women after menopause. 2-Hydroxyestradiol might be applied also to men.

18

Effect of unilateral ovariectomy on counter-current transfer of prostaglandin F2alpha in the area of mesometrium vasculature in the pig

51%

Stefanczyk-Krzymowska S. , Grzegorzewski W. , Skipor J. , Krzymowski T.

Bulletin of the Polish Academy of Sciences. Biological Sciences

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1992

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tom 40

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nr 1

19

The effects of male gender and female sex hormone deficiency on the vascular responses of the rat in vitro

51%

Nevala R. , Paakkari I. , Tarkkila L. , Vapaatalo H.

Journal of Physiology and Pharmacology

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1996

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tom 47

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nr 3

20

Wplyw niedoboru estrogenow na zawartosc cynku w zebach i zuchwie szczurow po ovariektomii

44%

Rahnama M. , Bloniarz J.

Bromatologia i Chemia Toksykologiczna

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2002

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tom 35

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nr 1

75-80

PL

Przy użyciu absorpcyjnej spektrometrii atomowej oznaczono zawartość cynku w kości żuchwy i w zębach samic szczurów po usunięciu jajników oraz po zastosowaniu doświadczalnej estrogenowej terapii zastępczej. Niedobór estrogenów prowadził do obniżenia się poziomu cynku w twardych tkankach narządu żucia, w porównaniu z grupą kontrolną. Podawanie 17ß-estradiolu wstrzymywało proces demineralizacji związany z niskim poziomem estrogenów i powodowało wzrost zawartości cynku w materiale.

EN

Estrogen deficiency appearing after menopause or ovariectomy leads to osteopenia and osteoporosis. Such conclusion has been confirmed by non-invasive examinations of the skeletal, maxillary and mandible bones and teeth. Demineralisation of the hard tissues was heretofore attributed to the loss of calcium and phosphorus, while the role of microelements (e.g. Zn) was not completely explained. This experiment attempts to explain zinc behaviour in the structure of the masticatory system when the level of estrogens is reduced. Female Wistar rats were used in the experiment. They were divided into seven groups as follows: CL - control, SH - sham operated, OV - after ovariectomy, OVO - ovariectomised rats which were injected oleum pro injectione, OVH1-OVH3 - rats receiving twice a week 3 different (1.25 µg, 12.5 µg and 125 µg) doses, respectively, of 17β-estradiol. Zinc level after ovariectomy was lower than in the control both in the teeth and in the mandible. The differences were statistically significant. Administration of 17β-estradiol to the ovariectomised rats produced a slight increase in Zn level. These results may suggest that ovarian estrogens play an important role in mineralisation of bones and teeth, and therefore, in post-menopausal osteoporosis prevention.