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EN
The aim of this study was to evaluate the efficacy of oral application of iron polymaltose complex (IPC) in the prevention of iron deficiency in piglets. The piglets in group I (n = 15) were treated with iron dextran (200 mg of Fe³⁺, i.m.) at the age of 3 d. In group II (n = 19), the piglets were given 100 mg of Fe³⁺ as IPC orally at the age of 3 and 11 d. The piglets in group III (n = 19) received oral application of 100 mg of Fe²⁺ ferrous fumarate at the age of 3 and 11 d. The piglets in group IV (n = 12) served as an iron deficient control group. The haemoglobin concentration and iron concentration in blood plasma in IPC treated group were comparable to the ferrous fumarate group. It is concluded that the IPC showed a comparable efficacy of IPC in the anaemia prevention as ferrous fumarate.
EN
Two organic compounds of selenium, 4-o-totyl-selenosemicarbazide p-chlorobenzoic acid (chain compound) produced at the Chemistry Department of the University Medical School in Lublin, and one inorganic compound of sodium IV selenite (Na2SeO3) were used. The preparations were used per os in doses of 1 mg/kg body weight and 0.5 mg/kg body weight. The studies were conducted on female Swiss mice, covering seven groups of animals, i.e. 6 experimental and 1 control. Histopathologic changes were observed in liver, kidney, lung and heart. Ultrastructural changes were observed in liver and kidney. Our studies indicate a dose-dependent effect of selenium on histopathologic and ultrastructural changes. It is possible therefore, that the extent of excess of selenium exerts a greater influence on a cell than the form of supplemented selenium.
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