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Epidemiological investigation of Toxoplasma gondii infections in commercial sheep flock in an endemic area for ocular toxoplasmosis in Southern Brazil

100%

Consalter A. , Frazao-Teixeira E. , Dubey J. P. , Zanella E. L. , da Silva A. F. , de Souza G. N. , Ferreira A. M. R.

Acta Parasitologica

2019

tom 64

nr 3

Molecular analysis of Dirofilaria repens isolates from eye-care patients in Greece

100%

Bozidis P. , Sakkas H. , Pertsalis A. , Christodoulou A. , Kalogeropoulos C. D. , Papadopoulou C.

Acta Parasitologica

2021

tom 66

nr 1

Onchocerca lupi infection in Turkey: A unique case of a rare human parasite

100%

Ilhan H. D. , Yaman A. , Morishima Y. , Sugiyama H. , Muto M. , Yamasaki H. , Hasegawa H. , Lebe B. , Bajin M. S.

Acta Parasitologica

2013

tom 58

nr 3

Onchocerpa lupi was first isolated from a wolf in Russia. Since then, canine ocular onchocercosis has been increasingly reported, particularly in Europe and the United States. It is thought that blackflies and midges are the vectors of transmission, and it is possible that these vectors could transmit the parasite to humans. The first human case of O. lupi in Turkey was reported in 2011. In this report we present the third human case of O. lupi infection in Turkey. Our patient was a 28-year-old male who displayed a painless, immobile mass under the conjunctiva. The mass measured 10 × 12 mm in size. Pathological examination of the surgically excised tissue was suggestive of infection by a filarial nematode. Subsequently, the parasite was identified as O. lupi through molecular analysis. All of the previously reported cases of O. lupi in both humans and dogs were more symptomatic than in our patient, Onchocerca infection should not be ruled out during the differential diagnosis of the subconjunctival and orbital cystic mass in instances where there is little to no inflammation. It is important to consider biopsy and carry out molecular analysis to identify the parasite.

Metastasis inhibition after proton beam, beta- and gamma-irradiation of melanoma growing in the hamster eye

80%

Romanowska-Dixon B. , Elas M. , Swakon J. , Sowa U. , Ptaszkiewicz M. , Szczygiel M. , Krzykawska M. , Olko P. , Urbanska K.

Acta Biochimica Polonica

2013

tom 60

nr 3

Standard ocular tumor treatment includes brachytherapy, as well as proton therapy, particularly for large melanoma tumors. However, the effects of different radiation types on the metastatic spread is not clear. We aimed at comparing ruthenium (106Ru, emitting β electrons) and iodine (125I, γ-radiation) brachytherapy and proton beam therapy of melanoma implanted into the hamster eye on development of spontaneous lung metastases. Tumors of Bomirski Hamster Melanoma (BHM) implanted into the anterior chamber of the hamster eye grew aggressively and completely filled the anterior chamber within 8-10 days. Metastases, mainly in the lung, were found in 100% of untreated animals 30 days after enucleation. Tumors were irradiated at a dose of 3-10 Gy with a 106Ru plaque and at a dose of 6-14 Gy using a 125I plaque. The protons were accelerated using the AIC-144 isochronous cyclotron operating at 60 MeV. BHM tumors located in the anterior chamber of the eye were irradiated with 10 Gy, for the depth of 3.88 mm. All radiation types caused inhibition of tumor growth by about 10 days. An increase in the number of metastases was observed for 3 Gy of β-irradiation, whereas at 10 Gy an inhibition of metastasis was found. γ-radiation reduced the metastatic mass at all applied doses, and proton beam therapy at 10 Gy also inhibited the metastastic spread. These results are discussed in the context of recent clinical and molecular data on radiation effects on metastasis.

Cyclodialysis in the treatment of nonhealing secondary glaucoma

80%

Lew M. , Lew S.

2008

tom 11

nr 4

371-375

In cases of glaucoma with elevated intra ocular pressure, the first objective of treatment is its reduction and normalization. In cases when excessive pressure has resulted in a loss of vision, the aim of treatment is to attenuate the pain and to improve the comfort of the patient. This paper presents a case of glaucoma secondary to anterior uveitis, resistant to pharmacological treatment. A gonioscopic examination in both eyes revealed a narrowed filtration angle. An ophthalmoscopic examination of the fundus showed partial retinal detachment. The cyclodialysis procedure was performed in both eyes. In the post-surgery period, intraocular pressure (IOP) in both eyes showed a downward tendency. The treatment of glaucoma secondary to anterior uveitis, particularly in its advanced state, often requires the combination of pharmacological treatment with a surgical procedure. Positive results in maintaining the patency of the fistula were observed after the application of a steroid therapy and a regular massage of filtration bleb, which significantly contributed to maintaining IOP at a desired level.