Wyniki wyszukiwania - Biblioteka Nauki

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The influence of Finnish sauna treatments on the concentrations of nitric oxide, 3-nitrotyrosine and selected markers of oxidative status in training and non-training men

100%

Gryka D. , Pilch W. , Czerwińska-Ledwig O. , Piotrowska A. , Klocek E. , Bukova A.

International Journal of Occupational Medicine and Environmental Health

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2020

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tom 33

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nr 2

173-185

EN

ObjectivesThe aim of the study was to evaluate the effects of repeated Finnish sauna baths on the concentrations of nitric oxide metabolites (NOx) and 3-nitrotyrosine in relation to pro-oxidative and antioxidative status in young males with different physical activity levels.Material and MethodsThe study was performed on healthy males (aged 20–25 years), representing the training (T, N = 10) and non-training groups (NT, N = 10). The protocol included a series of 10 sauna baths during 3 weeks. One bath consisted of three 15-min sessions, with 2 min recovery. Before the first and the 10th treatment, measurements of body composition, blood pressure, rectal temperature, and plasma concentrations of the total pro-oxidative and antioxidative status, 3-nitrotyrosine and NOx were performed.ResultsA significant increase in physiological parameters during sauna treatments, as well as a significant decrease in the total antioxidative status before the 10th bath, were observed in both groups. The series of sauna baths caused a significant increase in the total antioxidative status in the T group, and a decrease in the total oxidative status in the NT group. A significant decrease in 3-nitrotyrosine in both groups before the last treatment, and also in the T group after the last treatment, was noted. In both groups, a significant increase in NOx concentrations was observed after the first bath.ConclusionsA series of sauna baths contributes to the improvement in the prooxidative/antioxidative balance. The increased production of nitric oxide may lead to a better vascular relaxation and blood flow.

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Assessment of oxidative/nitrosative stress biomarkers and DNA damage in Haemonchus contortus, following exposure to zinc oxide nanoparticles

84%

Esmaeilnejad B. , Samiei A. , Mirzaei Y. , Farhang-Pajuh F.

Acta Parasitologica

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2018

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tom 63

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nr 3

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Quercetin in association with moderate exercise training attenuates injuries induced by experimental diabetes in sciatic nerves

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Chis I. C. , Clichici A. , Nagy A. L. , Oros A. , Catoi C. , Clichici S.

Journal of Physiology and Pharmacology

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2017

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tom 68

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nr 6

4

Cereal grass juice in wound healing: hormesis and cell-survival in normal fibroblasts, in contrast to toxic events in cancer cells

84%

Karbarz M. , Mytych J. , Solek P. , Stawarczyk K. , Tabecka-Lonczynska A. , Koziorowski M. , Luczaj L.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 4

5

Galectin-3 deficiency reduces cardiac and renal antioxidant capacity in mice

84%

Vucevic D. B. , Borozan S. Z. , Radenkovic A. S. , Radosavljevic M. I. , Mladenovic D. R. , Jorgacevic B. Z. , Samardzic J. M. , Veskovic M. N. , Vukicevic D. V. , Radosavljevic T. S.

Folia Biologica

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2020

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tom 68

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nr 2

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Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia

84%

Zayachkivska O. , Gzregotsky M. , Ferentc M. , Yaschenko A. , Urbanovych A.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 2

EN

Experimental and clinical gastrointestinal data reported that nitrosative stress development involved in impaired barrier function, altered motility and a lowered threshold to noxious stimuli, but its pathogenetic role in diabetic esophagopathy remains unexplored. We tested the hypothesis that an imbalance in nonenzymatic glycation and glycooxidation, enhanced peroxynitrite formation, may play an important role in development esophageal mucosa (EM) lesions during streptozotocin-induced experimental hyperglycemia (EHG). To understand the biological significance of EM resistance in vivo used a glycomic approach to identification of lectin receptors glycosylation pattern. Were enrolled rat groups without/with EHG & modification of NO/NOS activity by L-arginine (L-arg) and indomethacin pre-treatment. Survival rate, destruction occurrence ratio, the size of EM lesions, and the number of EM lesions was investigated. To access the oligosaccharide residues the peroxidaseconjugated lectin (HPA, SNA, WGA, PNA)-diaminobenzidine procedure was performed to EM sections. EHG was monitored daily by glucometer. Content of NO (NOn) was determinated by Griess reagent and reactive oxygen-scavenging systems (ROSS) activity - generally accepted biochemical methods. In EHG and L-arg pretreatment group reduced NOn and EM injury with markedly rise ROSS activity significantly vs to control; in the group with indomethacin pretreatment existed different ROSS activity. Presence of heterogeneous glycosylation pattern in different layers of EM was shown. In EHG staining with PNA and SNA were strongly positive. NS and ROSS play a critical role in esophagoprotection induced by EHG, because both involved increases in iNOS expression. These results indicate the usefulness of glycomic approach as multifunctional substrate of early evaluation of NS in esophageal physiopathy.

7

Effects of cigarette smoke borne reactive nitrogen species on salivary alpha-amylase activity and protein modifications

67%

Weiner D. , Khankin E. V. , Levy Y. , Reznick A. Z.

Journal of Physiology and Pharmacology. Supplement

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2009

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tom 60

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nr 5

8

Oxidative and nitrosative stress on phagocytes’ function: from effective defense to immunity evasion mechanisms

59%

Ferrari C. K. B. , Souto P. C. S. , Franca E. L. , Honorio-Franca A. C.

Archivum Immunologiae et Therapiae Experimentalis

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2011

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tom 59

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nr 6