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Czasopisma help
  1. 49 Archivum Immunologiae et Therapiae Experimentalis
  2. 12 Journal of Physiology and Pharmacology
  3. 10 Folia Histochemica et Cytobiologica
  4. 9 Journal of Physiology and Pharmacology. Supplement
  5. 7 Cellular and Molecular Biology Letters
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  1. 1 2022
  2. 2 2020
  3. 3 2018
  4. 4 2017
  5. 3 2015
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  1. 14 Jablonska E.
  2. 8 Jablonski J.
  3. 6 Garley M.
  4. 5 Tchorzewski H.
  5. 5 Zak-Nejmark T.
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1
Hypochlorous acid inhibits glutathione S-conjugate transport
100%
Soszynski M. , Zavodnik I. , Zavodnik L. B. , Zylinska L. , Bartosz G. , Bryszewska M.
Cellular and Molecular Biology Letters
|
2002
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tom 07
|
nr Suppl.
2
Effect of physical exercise on oxygen metabolism of neutrophils in horses
88%
Krumrych W.
Bulletin of the Veterinary Institute in Puławy
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2009
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tom 53
|
nr 1
97-103
EN
The study included 114 clinically healthy horses representing different groups: breeding horses (27), recreation horses (22), and sport horses (65). The group of sport horses consisted of racehorses (11), trotters (15), jumping horses (25), and driving horses (14). The peripheral blood samples collected three times: before exercise, immediately after exercise, and after 30-min rest were examined for the activity of oxygen metabolism of neutrophils using chemiluminescence (CL). The study demonstrated a temporary post-exercise intensification of free radical processes in sport horses. The intensity of this reaction depended on the intensity and duration of the exercise workload, which was confirmed by the changes in the heart rate and breathing. The analysis of the results of pre-exercise examination demonstrated clearly higher CL values of neutrophils in horses trained regularly and intensively than in animals of small physical activity. This result proves a positive influence of regular training on oxygen-dependent bactericidal activity of neutrophils.
3
Content available Extrathoracic negative pressure ameliorates lung injury during mechanical ventilation in experimental pigs
88%
Wessely-Szponder J. , Szponder T. , Fijalkowska-Nestorowicz A. , Bobowiec R. , Sobczyńska A. , Wessely-Szponder J. , Szponder T. , Fijalkowska-Nestorowicz A. , Bobowiec R. , Sobczyńska A.
|
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tom 21
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nr 4
4
Content available The role of the hematological inflammatory index and systemic immuno-inflammation index in acute cholecystitis
88%
Özdemir S. , Altunok İ. , Özkan A. , Muzaffer İslam M. , Algın A. , Emre Eroğlu S. , Aksel G.
European Journal of Clinical and Experimental Medicine
|
2022
|
nr 3
330-335
EN
Introduction and aim. Acute cholecystitis is one of the most common hepatobiliary emergencies. We aimed to investigate the role of the initial hematological inflammatory index and systemic immuno-inflammation index in predicting short-term mortality in patients with acute cholecystitis. Material and methods. This study with a retrospective observational design was conducted at the emergency department of a tertiary teaching hospital. Patients admitted to our clinic between June 15, 2021, and March 15, 2022, according to the Tokyo criteria were included in the sample. The hematological inflammatory index and systemic immuno-inflammation index were calculated using the hematological test results of the patients evaluated at the emergency department. Survivor and non-survivor groups were formed according to all-cause 30-day mortality. The differences between survivor and non-survivor groups were investigated. Results. A total of 194 patients were included in the final analysis. The median age of the study population was 59 (25th–75th percentiles: 46.75–72) years. The rate of all cause-short-term mortality was 7.7. There were significant differences between the survivor and non-survivor groups in terms of the neutrophil count and the systemic immuno-inflammation index (p=0.007, 0.034, respectively; Mann-Whitney U test). No significant difference was found in the remaining laboratory parameters (lymphocyte count, platelet count, and hematological inflammatory index) (p=0.220, 0.489, 0.367 respectively; Mann-Whitney U test). Conclusion. The systemic immuno-inflammation index was determined to be significantly higher in the non-survivor group than in the survivor group among the patients with acute cholecystitis. However, there was no significant difference between these two groups in relation to the hematological inflammatory index
5
INOS expression and NO production by neutrophils in cancer patients
88%
Jablonska E. , Puzewska W. , Marcinczyk M. , Grabowska Z. , Jablonski J.
Archivum Immunologiae et Therapiae Experimentalis
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2005
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tom 53
|
nr 2
6
Motile membrane skeletons: what neutrophils and muscles have in common
88%
Luna E. J. , Pestonjamasp K. N. , Nebl T. , Chen Y. , Gatto C. , Oh S. W. , Pope R. K.
Cellular and Molecular Biology Letters
|
2001
|
tom 06
|
nr 2
7
Depletion of head kidney neutrophils and cells with basophilic granules during peritoneal inflammation in the goldfish, Carassius auratus
88%
Bielek E. , Bigaj J. , Chadzinska M. , Plytycz B.
Folia Biologica
|
1999
|
tom 47
|
nr 1-2
8
Content available remote Influence of 5-aminoisoquinolin-1-one (5-AIQ) on neutrophil chemiluminescence in rats with transient and prolonged focal cerebral ischaemia and after reperfusion
75%
Hendryk S. , Czuba Z. P. , Jedrzejowska-Szypulka H. , Szliszka E. , Phillips V. A. , Threadgill M. D. , Krol W.
Journal of Physiology and Pharmacology
|
2008
|
tom 59
|
nr 4
811-822
EN
Stimulation of neutrophils by different factors increases their oxidative activity and the free radicals produced can report on the degree of activation. Poly(adenosine 5’-diphosphate ribose)polymerase-1 (PARP-1), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the tissue injury associated with ischaemia-reperfusion injury and inflammation. 5-Aminoisoquinolin-1-one (5-AIQ) is a potent inhibitor of PARP-1 activity in vitro and in vivo in rats. Acute (80 min) and prolonged (24h) focal cerebral ischaemia was induced in rats by obstruction of the median cerebral artery, with or without reperfusion, with or without administration of 5-AIQ. The oxidative activity of neutrophils was measured by chemiluminescence. Administration of 5-AIQ.HCl (3.0 mg kg-1 b.w. - i.v.) caused a significant decrease in the oxidative activity of neutrophils in the group which had experienced chronic ischaemia for 24h but had no significant effect in the group which had received 80 min ischaemia, when compared to the control group. Increase of the oxidative activity of neutrophils was confirmed in rats with prolonged cerebral ischaemia, followed by reperfusion. 5-AIQ probably may decrease this activity through inhibition of PARP-1 in focus of local ischaemia as well as hence lowering the expression of inflammatory mediators by activated neutrophils.
9
Content available remote Reduction of oxidative stress in adjuvant arthritis. Comparison of efficacy of two pyridoindoles: stobadine dipalmitate and SMe1.2HCl
75%
Ponist S. , Mihalova D. , Jancinova V. , Snirc V. , Ondrejickova O. , Mascia C. , Poli G. , Stancikova M. , Nosal R. , Bauerová K.
Acta Biochimica Polonica
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2010
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tom 57
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nr 2
223-228
EN
The aim of this study was to evaluate the therapeutic potential of oxidative stress (OS) reduction by using pyridoindole (PI) antioxidants in adjuvant arthritis (AA). The substances tested were stobadine dipalmitate (STB) and SMe1. AA was used as animal model. The experiments included healthy animals, control arthritic animals and arthritic animals with administration of PI in the oral daily dose of 15 mg/kg b.m during 28 experimental days. The rats were sacrificed on day 28. Clinical and biochemical parameters were determined. The effect of PI administration was evaluated on the basis of the following parameters: (a) arthritis (volume of hind paws - HPW, change of animal body mass - CBM), (b) OS (chemiluminescence of whole blood - CWB, levels of thiobarbituric acid reacting substance - TBARS and of HNE- and MDA-protein adducts in plasma and activity of γ-glutamyltransferase (GGT) in hind paw joint homogenates). The PI studied significantly increased the CBM of animals and corrected the HPW. STB also significantly decreased the activity of GGT in joint homogenates. SMe1 was more effective in decreasing plasmatic TBARS levels, but STB was more effective in reducing plasmatic HNE- and MDA-protein adducts. The assay for HNE- and MDA-adducts in plasma as a function of time was applied for the first time in AA. STB markedly decreased spontaneous and PMA-stimulated CWB and reduced neutrophil count. In summary, STB was more effective than SMe1 in reducing OS in AA. Our results showed that the reduction of OS in arthritis also corrected the clinical manifestations of the disease.
10
Content available Phagocytosis of neutrophils in rabbits infected with antigenic variants of RHD (rabbit haemorrhagic disease) virus
75%
Niedzwiedzka-Rystwej P. , Deptula W.
Polish Journal of Veterinary Sciences
|
2012
|
tom 15
|
nr 1
EN
The present study was aimed at determining changes in chosen elements of phagocytosis in rabbits infected with 3 antigenic variants of RHD – Hartmannsdorf, Pv97 and 9905, which differed in haemagglutination ability. The animals were tested for phagocytosis parameters, and the results revealed that the examined strains showed the differences. These variations regarded mainly Pv97 strain, as the intensity of the changes were 5 times stronger in comparison to strain Hartmannsdorf and 9905. As all of the strains examined are signified as antigenic variants, we have stated that this feature does not determine their immunological picture. The results suggest the existence of immunological dissimilarities among strains of the RHD virus, which was revealed for the first time in antigenic variants.
11
Content available Changes in innate and adaptive immune response to Lagovirus europaeus GI.1 (Rabbit Haemorrhagic Disease Virus -RHDV) infection
75%
Hukowska-Szematowicz B.
Acta Biologica
|
2020
|
tom 27
12
Antagonizing retinoic acid receptors increases myeloid cell production by cultured human hematopoietic stem cells
75%
Brown G. , Marchwicka A. , Cunningham A. , Toellner K.-M. , Marcinkowska E.
Archivum Immunologiae et Therapiae Experimentalis
|
2017
|
tom 65
|
nr 1
13
Effect of magnetic field, the red light and their combination on the oxygen-dependent mechanism of killing of neutrophils
75%
Nawrocka–Bogusz H. , Jaroszyk F. , Michalak K. P.
Current Topics in Biophysics. Supplement
|
2011
|
tom 34
|
nr A: Posters
14
Content available remote Eosinophilic airway inflammation in chronic obstructive pulmonary disease and asthma
75%
Gorska K. , Krenke R. , Korczynski P. , Kosciuch J. , Domagala-Kulawik J. , Chazan R.
|
|
nr 6
261-270
15
Role of the p38 MAPK pathway in induction of iNOS expression in human leukocytes
75%
Jablonska E. , Ratajczak W. , Jablonski J.
Folia Biologica
|
2008
|
tom 56
|
nr 1-2
83-89
16
Content available remote Proinflammatory genes expression in granulocytes activated by native proteinase-binding fragments of anti-proteinase-3 IgG
75%
Surmiak M. , Kaczor M. , Sanak M.
Journal of Physiology and Pharmacology
|
2015
|
tom 66
|
nr 4
17
Formation of lipid droplets induced by 2,3-dihydrogeranylgeranoic acid distinct from geranylgeranoic acid
75%
Kodaira Y. , Kusumoto T. , Takahashi T. , Matsumura Y. , Miyagi Y. , Okamoto K. , Shidoji Y. , Sagami H.
Acta Biochimica Polonica
|
2007
|
tom 54
|
nr 4
777-782
EN
Geranylgeranoic acid (GGA) and 2,3-dihydrogeranylgeranoic acid (2,3-diGGA) are geranylgerani-ol-derived metabolites (Kodaira et al.(2002) J Biochem132:327–334). In the present study, we examined the effects of these acids on HL-60 cells. The cells were differentiated into neutrophils by GGA stimulation like retinoic acid stimulation. In the case of cells stimulated with 2,3-diGGA, neutrophils were not detected, but the formation of lipid droplets was induced. On the other hand, when the cells were cultured in the presence of 0.1% FBS instead of 10% FBS, apoptotic cells were induced not only by GGA stimulation but also with 2,3-diGGA. In the latter case, when the cells were cultured in the co-presence of a caspase-3 inhibitor (Ac-DMQD-CHO), the lipid droplets formation was observed in the cells. These results suggest that GGA and 2,3-diGGA are extremely different from each other with respect to their effects on HL-60 cells.
18
Regulation of the NADPH oxidase activity and anti-microbial function of neutrophils by arachidonic acid
75%
Hii C. S. , Ferrante A.
Archivum Immunologiae et Therapiae Experimentalis
|
2007
|
tom 55
|
nr 2
19
Quantitative analysis of LacCer-CDw17 in human myelogenous leukaemic cells
75%
Spychalska J. , Smolenska-Sym G. , Zdebska E. , Wozniak J. , Koscielak J.
Cellular and Molecular Biology Letters
|
2003
|
tom 08
|
nr 4
EN
LacCer/CDw17 is the most abundant GSL in neutrophils. The cell-surface and intracellular presence of LacCer was determined quantitatively using anti-CDw17 mAbs in a flow cytometry assay. The quantified alterations in the level of CDw17 antigen expression are consistent with alterations in LacCer content, determined chemically. Our results show that CDw17 antigen expression defines successive stages in the maturation of the myeloid cell. The assessment of cell-surface and intracellular CDw17 expression may be useful in evaluating neutrophil physiological status.
20
Respiratory burst of the neutrophils in ischemic heart disease patients
75%
Baj Z. , Kantorski J. , Kowalski J. , Kosmider M. , Tchorzewski H. , Pawlicki L. , Ciecwierz J.
|
|
tom 18
|
nr 2
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