Wyniki wyszukiwania - Biblioteka Nauki

1

The role of photodynamic therapy in the vulvar neoplasia and non-neoplasmatic conditions

100%

Pałczyński B. , Ekonjo G. , Gryboś M.

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

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2004

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tom Vol. 10, nr 1-2

52-52

2

A morphometric study of nucleolar organiser regions in cervical intraepithelial neoplasia

100%

Terlikowski S. , Dzieciol J. , Mazurek A. , Sulkowski S. , Boron R. , Oniszczuk M. , Lejmanowicz K.

Folia Morphologica

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2004

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tom 63

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nr 2

EN

The study sought a correlation between the number of AgNOR granules and the degree of cervical intraepithelial neoplasia (CIN). Thirty-five sections (5 normal, 10 CIN1, 10 CIN2 and 10 CIN3) were subjected to retrospective analysis. The percentage of cells with 1, 2, 3, 4 and more AgNORs was calculated and the number of granules per 100 cells was counted. The number of cells containing single granules decreases. However, the number increases with CIN level when the cells contain 4 and more AgNORs. The number of granules per 100 cells also increases with the degree of CIN. It can be thus concluded that the number of cells with 4 and more AgNOR granules can serve as a CIN differentiation exponent.

3

An unusual presentation of corneal intraepithelial neoplasia

88%

Marticorena-Álvarez P. , Garrido Ceca G. , Celdrán Vivancos D. A.

OphthaTherapy

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2020

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tom 7

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nr 4

302-304

EN

Introduction: Conjunctival/corneal intraepithelial neoplasms are premalignant lesions usually showing conjunctival or limbal involvement. We report the rare case of an isolated corneal intraepithelial lesion. Clinical case: An 80-year-old woman with an elevated, avascular, well-demarcated grey corneal plaque. After epitheliectomy and alcohol, the excised lesion was identified as a high-grade epithelial neoplasia. Treatment was topical interferon α-2b for 1 month without recurrences. Conclusions: A well-defined greyish corneal opacity should always raise suspicion of an intraepithelial neoplasia. In the present case, epitheliectomy and topical recombinant interferon proved successful.

4

On the relationship between fractal geometry of space and time in which a system of interacting cells exists and dynamics of gene expression.

88%

Waliszewski P. , Molski M. , Konarski J.

Acta Biochimica Polonica

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2001

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tom 48

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nr 1

209-220

EN

We report that both space and time, in which a system of interacting cells exists, possess fractal structure. Each single cell of the system can restore the hierarchical organization and dynamic features of the entire tumor. There is a relationship between dynamics of gene expression and connectivity (i.e., interconnectedness which denotes the existence of complex, dynamic relationships in a population of cells leading to the emergence of global features in the system that would never appear in a single cell existing out of the system). Fractal structure emerges owing to non-bijectivity of dynamic cellular network of genes and their regulatory elements. It disappears during tumor progression. This latter state is characterized by damped dynamics of gene expression, loss of connectivity, loss of collectivity (i.e., capability of the interconnected cells to interact in a common mode), and metastatic phenotype. Fractal structure of both space and time is necessary for a cellular system to self-organize. Our findings indicate that results of molecular studies on gene expression should be interpreted in terms of space-time geometry of the cellular system. In particular, the dynamics of gene expression in cancer cells existing in a malignant tumor is not identical with the dynamics of gene expression in the same cells cultured in the monolayer system.

5

Enlarged prostate lesions of pure-bred and mongrel dogs

75%

Bauzaite N. , Aniuliene A.

Medycyna Weterynaryjna

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2003

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tom 59

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nr 08

686-690

6

Ovarian neoplastic changes in dairy cows with adenomyosis - histopathological study

75%

Katkiewicz M.

Journal of Veterinary Research

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2020

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tom 64

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nr 3

7

Alzheimer's disease and the cell cycle

75%

Raina A. K. , Zhu X. , Smith M. A.

Acta Neurobiologiae Experimentalis

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2004

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tom 64

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nr 1

8

On the relationship between fractal geometry of space and time in which a system of interacting cells exists and dynamics of gene expression

75%

Waliszewski P. , Molski M. , Konarski J.

Acta Biochimica Polonica

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2001

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tom 48

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nr 1

EN

We report that both space and time, in which a system of interacting cells exists, possess fractal structure. Each single cell of the system can restore the hierarchical organization and dynamic features of the entire tumor. There is a relationship between dynamics of gene expression and connectivity (i.e., interconnectedness which denotes the existence of complex, dynamic relationships in a population of cells leading to the emergence of global features in the system that would never appear in a single cell existing out of the system). Fractal structure emerges owing to non-bijectivity of dynamic cellular network of genes and their regulatory elements. It disappears during tumor progression. This latter state is characterized by damped dynamics of gene expression, loss of connectivity, loss of collectivity (i.e., capability of the interconnected cells to interact in a common mode), and metastatic phenotype. Fractal structure of both space and time is necessary for a cellular system to self-organize. Our findings indicate that results of molecular studies on gene expression should be interpreted in terms of space-time geometry of the cellular system. In particular, the dynamics of gene expression in cancer cells existing in a malignant tumor is not identical with the dynamics of gene expression in the same cells cultured in the monolayer system.

9

Recent trends in the prevalence of neoplasia in the Baltic clam Macoma balthica (L.) from the Gulf of Gdańsk (Baltic Sea)

75%

Smolarz K. , Thiriot-Quievreux C. , Wolowicz M.

Oceanologia

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2005

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tom 47

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nr 1

EN

This study discusses the occurrence of neoplasia in the Baltic clam Macoma balthica from the Gulf of Gdańsk in recent years and investigates potential relationships between toxic compounds in the environment and the presence of the cancer. The disease was identified at four sampling stations during 1999–2002. Comparison with previous results highlighted the substantial prevalence of the tumour between 1998 and 2002. The prevalence of the cancer was strongly dependent on the sampling location (p < 0.001): it was highest at sampling point H45 (the deepest part of the gulf) and lowest at station PB30 (central part of the gulf). Monthly studies showed a trend towards an increasing prevalence of neoplasia during the warm months. However, over several sampling months no strong statistical correlation between the prevalence of the disease and the sampling time was found. The results of the study suggest that several environmental factors may promote the progress of the cancer in M. balthica from the Gulf of Gdańsk: it is most probably an indirect effect of pollution, although causality cannot be proven at this stage. Seriously polluted and exhibiting a considerable asymmetry of contamination, the ecosystem of the gulf provides an ideal environment for testing potential cause-effect relationships between pollutants and their biological effects.

10

The expression profile of genes encoding tumor necrosis factor-alpha, interleukin-6 and their receptors in benign adrenal tumors

63%

Morawiec E. , Cholewa K. , Zenderowski M. , Batoryna O. , Waluga-Kozlowska E. , Komosinska-Vassev K. , Krol R. , Kajor M. , Olczyk P. , Waluga M.

Journal of Physiology and Pharmacology

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2020

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tom 71

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nr 4

11

Study of DNA topoisomerase IIalpha expression in canine lymphomas and its potential role as a marker of sensitivity to anthracycline-based chemotherapy in dogs

63%

Klimiuk P. , Lopuszynski W. , Bulak K. , Smiech A. , Brzana A.

Folia Histochemica et Cytobiologica

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2020

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tom 58

|

nr 1

12

Lobular neoplasia found on breast biopsy: marker of increased risk of malignancy or direct pre-cancerous lesion?

63%

Szynglarewicz B. , Matkowski R. , Halon A. , Kasprzak P. , Forgacz J. , Gisterek I. , Kornafel J.

Folia Histochemica et Cytobiologica

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2011

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tom 49

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nr 3

13

Thoracoscopic creation of a pericardial window in dogs

63%

Holak P. , Szalecki P. , Adamiak Z. , Chyczewski M. , Jalynski M.

Polish Journal of Veterinary Sciences

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2009

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tom 12

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nr 3

EN

A window in the pericardial sac was created by thoracoscopy in two dogs with diagnosed idiopathic haemorrhagic pericardial effusion (IHPE). Thoracoscopic access to the pericardial sac facilitated surgery and minimised the risk of complications associated with conventional thoracotomy.

14

Role of pericardial effusion in dogs with and without cardiac neoplaesia

63%

Bakirel U. , Ulgen S.

Medycyna Weterynaryjna

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2007

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tom 63

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nr 04

428-431

EN

In this research, LV systolic functions of the 14 mature dogs with idiopathic pericardial effusion (IHPE) and cardiac neoplaesia (CN) were examined. The dogs were between 1-16 years old, generally large breed and male. Signs of cardiomegaly were observed in the chest radiography and low amplitude QRS complexes in electrocardiograms. Pericardial effusion, cardiac masses and paradoxical motion were detected by 2D echocardiography. Left ventricle (LV) systolic functions were detected with M mode echocardiographic examinations. A statistical significance (p<0.001) was found between echo-free pericardial Space (EPS) and fractional shortening (FS%), ejection fraction (EF%), velocity of circumferential fiber shortening (VcF), in the dogs with IHPE. A distinction was also found between EPS and EF in the dogs with CN (p < 0.001). FS, EF and VcF were significantly decreased in the dogs with IHPE in contrast to the dogs with CN. It was detected that the systolic function of the left ventricle could be considerably disturbed by the excessive volume of the pericardial effusion, even if no cardiac tamponade occurred.

15

Molecular changes in thyroid neoplasia

63%

Jarzab B.

Folia Histochemica et Cytobiologica. Supplement

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2001

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tom 39

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nr 1

16

Cis-DDP induced alteration of DNA structure studied by scanning tunneling microscopy

63%

Zastawny T. H. , Olejniczak W. , Olinski R.

Acta Biochimica Polonica

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1993

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tom 40

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nr 4

EN

Scanning tunneling microscopy (STM) was used to study the structural changes of DNA induced by the antitumor drug cts-diamminedichloroplatinum. The STM image showed a dramatic structural perturbation of the DNA by complexed Pt with the characteristic bend of the double helix.

17

Morphological and histochemical studies of the endocrine pancreas in persistent hyperinsulinemic hypoglycemia

51%

Kunz J.

Folia Histochemica et Cytobiologica

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1984

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tom 22

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nr 3-4

18

Parallel manifestation of various types of tumours in canine testes

51%

Nowaczyk R. , Nowak M. , Madej J. P.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2007

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tom 10

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nr 3

19

Diagnostic markers for germ cell neoplasms: from placental-like alkaline phosphatase to micro-RNAs

51%

Rajpert-De Meyts E. , Nielsen J. E. , Skakkebaek N. E. , Almstrup K.

Folia Histochemica et Cytobiologica

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2015

|

tom 53

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nr 3

20

The most common eye disease in cat

51%

Trbolova A.

Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii

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2011

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nr 2

PL

Wiele chorób oczu kotów różni się od tych które spotykamy u inny gatunków zwierząt. Typowo kocim schorzeniem jest sequestrum czyli martwak rogówki. Ogólne objawy ze strony oczu kota są zwykle powiązane z istnieniem choroby systemowej, toczącej się w całym organizmie (choroby tła wirusowego, pasożytnicze, grzybice, nadciśnienie). Oczy kotów wrażliwe są na niedobory tauryny czy też tiaminy, które to powodują zmiany chorobowe dna oka prowadzące do ślepoty. Bardzo często spotykamy u kotów nowotwory, które są zwykle bardziej agresywne niż u innych gatunków zwierząt. Ponadto występują też schorzenia o podłożu genetycznym i wady rozwojowe.