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Introduction: Cystic hygromas are very uncommon malformations in adults. In most of the cases, they present as a painless, fluctuant swelling, usually located in the neck region. They tend to grow extensively if not removed. Cystic hygromas can range from 1 mm to several centimeters in size and are filled with clear- to straw-colored fluid. Surgical treatment remains the gold-standard treatment for these tumors. In some cases they can be misdiagnosed with branchial cysts, swollen lymph nodes or other pathologies. When this malformation is present in the prevertebral fascia its surgical treatment is challenging, and some authors advise its conservative treatment, which is in a great risk of its reoccurence. Because of potential malignant transformation in some percentage of branchial cyst cases, a similar situation was suspected. Case report: The present report describes a case of cystic hygroma of the left side of the neck in a 92-year-old female adult and its clinical, radiological and operative features.
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It is reasonable to suppose that airway mucosa can be damaged by irradiation applied to chest and neck regions. The inflammatory process is a consequence of an injury. Airway inflammation is one mechanism responsible for cough induction. So, one can suppose that radiotherapy (RT) focused on the patients' chest or neck may injure airway mucosa, which might change sensitivity of the nerve-endings mediating the cough reflex. The purpose of this study was to examine cough reflex sensitivity (CRS) in patients who underwent RT in the chest and neck regions. CRS test using capsaicin was performed in patients with breast cancer (Group A, n=19), and with lung or neck cancer in (Group B, n=14) who underwent RT. Capsaicin aerosol in doubled concentrations (0.49-1000 µM) was inhaled by a single breath. CRS was defined as the lowest capsaicin concentration that evoked 2 or more coughs (C2). Radiation doses ranged from 40 to 70 Gy. Capsaicin cough challenge was performed before and then in the 2nd and 5th week of RT. We observed a significantly reduced value of C2, i.e., increased cough reflex sensitivity, in Group B in the 2nd week of RT (P= 0.04). We conclude that CRS in the lung or neck cancer patients undergoing RT is significantly enhanced, which could result from injury to the nerve endings in airway mucosa.
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