PL
 |
EN
Ten serwis zostanie wyłączony 2025-02-11.
Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl
Preferencje help
Polish version English version Język
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 8

Liczba wyników na stronie
first rewind previous Strona / 1 next fast forward last
Wyniki wyszukiwania
Wyszukiwano:
w słowach kluczowych:  minimal residual disease
help Sortuj według:

help Ogranicz wyniki do:
first rewind previous Strona / 1 next fast forward last
1
Content available remote Usefulness of real-time PCR in long-term follow-up of follicular lymphoma patients
100%
Tysarowski A. , Fabisiewicz A. , Paszkiewicz-Kozik E. , Kulik J. , Walewski J. , Siedlecki J. A.
Acta Biochimica Polonica
|
2007
|
tom 54
|
nr 1
135-142
EN
The aim of this study was to evaluate the usefulness of quantitative real-time PCR (RQ-PCR) for the monitoring of molecular remission in follicular lymphoma (FL) patients during long-term follow-up. RQ-PCR by the use of TaqMan® detection system is a sensitive tool to monitor minimal residual disease (MRD) in FL through amplification of the t(14;18) fusion gene during and post-therapy. In most cases the breakpoint region occurs within the major breakpoint region (MBR). Among 75 patients diagnosed with FL, cells harboring the fusion gene BCL2/JH were found in peripheral blood of 31 patients (41%). We further monitored 30 of these patients in a period varying from 6 months to 5 years by RQ-PCR. In our study the level indicating the possibility of the presence of MRD was established at more than five t(14;18)-positive cells in the background of 83000 normal cells. The results of this work also confirmed that the presence of MRD detected by RQ-PCR is an indication for careful observation of patients because of a higher risk of disease recurrence.
2
Content available Molecular hematology – modern methodology serving patients and research
88%
Witt M.
Nauka
|
2009
|
nr 4
PL
The article describes a country-wide attempt to organize a network of laboratories performing molecular diagnostic procedures in a context of clinical hematology. The principles of construction of a commissioned grant in molecular hematology are presented. A major result of this project, the monographic book on molecular hematology is being announced.
3
Two methods for the quantitative analysis of surface antigen expression in acute myeloid leukemia [AML]
88%
Wozniak J.
|
|
nr 3
4
Usefulness od real-time PCR in long-term follow-up of follicular lymphoma patients
75%
Tysarowski A. , Fabisiewicz A. , Paszkiewicz-Kozik E. , Kulik J. , Walewski J. , Siedlecki J. A.
|
|
tom 54
|
nr 1
EN
The aim of this study was to evaluate the usefulness of quantitative real-time PCR (RQ-PCR) for the monitoring of molecular remission in follicular lymphoma (FL) patients during long-term follow-up. RQ-PCR by the use of TaqMan® detection system is a sensitive tool to monitor minimal residual disease (MRD) in FL through amplification of the t(14;18) fusion gene during and post-therapy. In most cases the breakpoint region occurs within the major breakpoint region (MBR). Among 75 patients diagnosed with FL, cells harboring the fusion gene BCL2/JH were found in peripheral blood of 31 patients (41%). We further monitored 30 of these patients in a period varying from 6 months to 5 years by RQ-PCR. In our study the level indicating the possibility of the presence of MRD was established at more than five t(14;18)-positive cells in the background of 83000 normal cells. The results of this work also confirmed that the presence of MRD detected by RQ-PCR is an indication for careful observation of patients because of a higher risk of disease recurrence.
5
Implementation of the standard strategy for identification of Ig-TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience
63%
Dawidowska M. , Jolkowska J. , Szczepanski T. , Derwich K. , Wachowiak J. , Witt M.
Archivum Immunologiae et Therapiae Experimentalis
|
2008
|
tom 56
|
nr 6
409-418
6
Content available Molecular follow up of donor lymphocyte infusion in CML children after allogeneic bone marrow transplantation
51%
Ladon D. , Pieczonka A. , Jolkowska J. , Wachowiak J. , Witt M.
|
|
tom 42
|
nr 4
7
Content available Monitoring of cellular chimerism in patients after sex-mismatched bone marrow transplantation: technical report
51%
Jolkowska J. , Ladon D. , Wachowiak J. , Witt M.
Journal of Applied Genetics
|
2000
|
tom 41
|
nr 3
8
Content available Mechanism, detection and significance of some chromosomal rearrangements in chronic myeloid leukaemia [CML] and acute lymphoblastic leukaemia [ALL]
51%
Ladon D. , Witt M.
Journal of Applied Genetics
|
2000
|
tom 41
|
nr 3
first rewind previous Strona / 1 next fast forward last
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.