A method for microbrids preparation has been presented. I allowed obtaining stuctures with 1 - 10 [mi]m diameters from the following polymers: cellulose, starch, sodium alginate, chitozane, creatine and cellulose carbaminate. It is supposed to use these features as carriers for various species among them bioactive molecules take the major place.
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Investigations are presented for the preparation of a model hemostatic dressing that would exhibit an adequate hemostatic capacity in injuries and surgical wounds, an antibacterial activity to prevent primary and secondary infections, and offer safety in use. The Hemoguard dressing has been designed as a powder prepared from the complex chitosan/alginate Na/Ca in the form of micro- and nano-fibrids. Useful antibacterial and hemostatic properties of Hemoguard, which would qualify the material as first aid dressing and a temporary protection of injury wounds in field conditions, were assessed. Biocompatibility of the dressing was confirmed by biological in vitro examinations.
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