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3 2020

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Efficacy of trifluridine/tipiracil as IV line chemotherapy in a young woman with metastatic colorectal cancer. A case report

100%

Wiśniowski R.

nr 1

23-26

Colorectal cancer is the most common gastrointestinal malignancy and the third most frequently diagnosed cancer worldwide. Trifluridine/tipiracil represents an approved option for the treatment of advanced metastatic colorectal cancer in patients who are refractory, or are not considered candidates for currently available therapies. We present a case of a young woman with refractory metastatic colorectal cancer treated with this agent as the IV line of chemotherapy in which remarkable prolongation of progression free survival time was observed.

TAS-102 – a new option in the treatment of patients with advanced colorectal cancer after failure or intolerance to other therapies

100%

Skalij P. , Tokajuk P. , Wojtukiewicz M. Z.

nr 1

8-14

Colorectal cancer is the second cause of death from malignant cancer, following lung cancer. Approximately 35–45% of patients with colorectal cancer will develop distant metastases over time. Palliative systemic treatment remains the standard for non-operative distant metastases. TAS-102 is a novel orally administered antineoplasmatic thymidine-based nucleoside analog which represents an approved option for the treatment of advanced metastatic colorectal cancer in patients who are refractory, or are not considered canditates for, currently available therapies.

Long-term disease control during TAS-102 therapy in the VI line treatment in a 73-year-old mCRC patient. A case report

100%

Skalij P. , Tokajuk P. , Jelski S. , Wojtukiewicz M.

nr 1

15-17

A case of 73-year-old patient with metastatic colorectal cancer who underwent trifluridine/tipiracil therapy within the VI line was presented. Treatment with trifluridine/tipiracil allowed to achieve stabilization of the existing cancer for nearly 7 months.