Wyniki wyszukiwania - Biblioteka Nauki

1

Normal levels of TSH affect the metabolic profile differently in physically active males and females

100%

Malara M. , Keska A. , Tkaczyk J. , Lutoslawska G.

Central European Journal of Sport Sciences and Medicine

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2021

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tom 35

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nr 03

2

The associations between the growth hormone/insulin-like growth factor-1 axis, adiponectin, resistin and metabolic profile in children with growth hormone deficiency before and during growth hormone treatment

75%

Witkowska-Sędek E. , Rumińska M. , Stelmaszczyk-Emmel A. , Majcher A. , Pyrżak B.

Acta Biochimica Polonica

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2018

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tom 65

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nr 2

333-340

EN

This study investigated associations between the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, adiponectin, resistin and metabolic profile in 47 GH-deficient children before and during 12 months of GH treatment. 23 short age-matched children without growth hormone deficiency (GHD) or any genetic or chronic disorders were recruited as controls at baseline. Metabolic evaluation included measurements of adiponectin, resistin, IGF-1, total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), glucose, insulin, glycated haemoglobin (HbA1c), thyroid stimulating hormone (TSH) and free thyroxine (free T4) concentrations. The GH-deficient children had significantly higher adiponectin (p<0.05) and total cholesterol (p<0.05) levels, and a significantly lower level of resistin (p<0.05) than the controls. Resistin at 6 months of GH treatment significantly correlated with changes in height SDS in that period (r=0.35) and with the level of fasting insulin (r=0.50), the HOMA-IR (r=0.56) and the QUICKI (r=-0.53) at 12 months of therapy. Adiponectin level at 12 months of GH treatment was significantly associated with changes in HDL-C within the first 6 (r=0.73) and within 12 (r=0.56) months of therapy, while resistin significantly correlated with an increment in IGF-1 within 12 months of treatment (r=0.49) and with total-C at 12 months (r=0.56). Untreated GH-deficient children had higher adiponectin and lower resistin levels than healthy short children without GHD. Adiponectin and resistin levels did not change significantly during the first 12 months of GH therapy. Good responders to GH treatment had a tendency for higher resistin level during GH therapy, which positively correlates with the insulin resistance parameters.

3

Characterization of Biofilms From Selected Synthetic Materials Used in Water Distribution System

75%

Biedroń I. , Traczewska T. , Konieczny T. , Płaza G.

Journal of Ecological Engineering

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2017

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tom Vol. 18, nr 1

284--293

EN

Materials like polyvinyl chloride (PVC), polypropylene (PP), ultra high molecular weight polyethylene (UHMW-PE) are used for the construction of drinking water supply systems. It was found that regardless of the type of material the distribution network is built of, microorganisms formed biofilms on every available surface. The pipes material plays a key role in terms of biofilm formation. Important factors are the surface roughness, adhesives, plasticizers, stabilizers, which can be a source of nutrients for bacteria. The metabolic activity of microorganisms on polymer materials, induces migration of compounds from the material into water. The aim of this study was to present the differences in the structure and the metabolic profile of biofilm formed on the technical materials.

4

Changes in urine metabolic profiles in patients with chronic intake of amphetamine and opiates revealed using 1H NMR spectroscopy with pattern recognition technique

75%

Janus T. , Borowiak K. , Rozwadowski Z. , Machoy-Mokrzynska A. , Suchocka J.

Acta Toxicologica

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2006

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tom 14

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nr 1-2

5

The evaluation of two production systems for growth and health of pigs

75%

Paska I. , Mlynek J. , Kovac L. , Nemcokova A.

Biuletyn Naukowy

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2000

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tom 07

6

Effect of glucogenic additive in transition dairy cow diets of varying ruminal starch degradability on blood metabolic profile

63%

Klebaniuk R. , Kowalczuk-Vasilev E. , Rocki G. , Matras J. , Olcha M. , Bakowski M.

Annales Universitatis Mariae Curie-Skłodowska. Sectio EE: Zootechnica

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2015

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tom 33

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nr 4

7

Metabolic profiling of Echinostoma caproni and Schistosoma mansoni in their definitive and intermediate hosts

63%

O’Sullivan C. , Fried B. , Sherma J.

Acta Parasitologica

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2013

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tom 58

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nr 1

EN

This review examines metabolic profiling of Schistosoma mansoni and Echinostoma caproni in their definitive and intermediate hosts. The earlier coverage of the literature on metabolic profiling was reviewed by Wang et al. 2010, Advances in Parasitology, 73, 373–404 and covered mainly studies using proton nuclear magnetic resonance spectroscopy. The methods focused upon in our review are mainly chromatographic. In the studies reviewed, various metabolites were analyzed in hosts infected with either E. caproni or S. mansoni and compared to the uninfected controls.

8

Metabolic profile and transgene stability evaluation

63%

Kulma A. , Kostyn K. , Szopa J.

Biological Letters

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2005

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tom 42

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nr 2 Spec.Vol.

9

Wykorzystanie systemu Biolog Ecoplate do monitorowania stanu ekotoksykologicznego osadów ściekowych (artykuł przeglądowy)

51%

Gryta A. , Frac M. , Oszust K. , Bilinska N.

Acta Agrophysica

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2013

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tom 20

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nr 3

PL

Rosnąca ilość osadów ściekowych i pofermentacyjnych stwarza konieczność ich racjonalnego zagospodarowania, gdyż składowanie może być niebezpieczne dla środowiska. Ze względu na zawartość w osadach materii organicznej oraz składników pokarmowych niezbędnych dla roślin mogą być one stosowane jako nawozy organiczne. Jednak poza cennymi substancjami osady mogą zawierać również składniki toksyczne i niebezpieczne. Dlatego też istnieje konieczność opracowania metod szybkiej oceny ekotoksyczności osadów, które pozwolą określić możliwość zastosowania danego osadu w rolnictwie. System Biolog Ecoplate® umożliwia ocenę profilu metabolicznego odzwierciedlającego stan aktywności populacji mikroorganizmów w próbkach środowiskowych. Jest to szybka i nowoczesna technika, która wykorzystując biologiczne właściwości pozwala charakteryzować stan ekologiczny próbek środowiskowych, tj. osady ściekowe i pofermentacyjne.

EN

Increasing amount of sewage sludge requires their reasonable management, whereas a storage might be environmentally hazardous. Due to organic matter and nutrients pres-ence in sludge, they may be used as organic fertilizers. However, beyond the valuable contests, sewage sludge can also contain toxic or dangerous components. Therefore, there is a need to develop methods for rapid assessment of sediments ecotoxicity, that will determine their possible ap-plicability in agriculture. The Biolog® Ecoplate enables the metabolic profiles diversity evaluation of microbial populations in environmental samples, which reflects the state of their activity. It is regarded as modern technology, that by means of biological properties allows quick characterization of the ecological status of environmental samples, such as sewage sludge.

10

Oleic acid as a biomarker for early diagnosis of elevated blood levels of non-esterified fatty acids and beta-hydroxybutyric acid in the early stages of lactation in high-yielding Polish Holstein cows

51%

Puppel K. , Solarczyk P. , Kuczynska B. , Madras-Majewska B.

Animal Science Papers and Reports

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2017

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tom 35

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nr 4

EN

Inappropriate doses and quality of dietary nutrients cause problems in providing the protein and energy balance in a feed ration. Especially, energy value of the feed ration poses many problems to dairy cattle breeders and particularly in the perinatal period, which results in increased incidence of metabolic disorders. These disorders are today one of the most frequent causes of culling of dairy cows, as they underlie most of the disease entities. The aim of this experiment was, therefore, to verify the hypothesis that oleic acid (OA) can be used as a biomarker for early diagnosis of elevated blood levels of non-esterified fatty acids (NEFAs) and β-hydroxybutyric acid (BHBA) in the early stages of lactation in high-yielding Polish Holstein (PHF) cows. The highest blood levels of NEFAs and BHBA of 1.573 and 1.116 mmolL⁻¹, respectively, was associated with the highest content of OA in milk fat. High concentrations of both NEFAs and BHBA, indicating explicitly the occurrence of the metabolic disease in cows, occur when the content of OA in milk exceeds 24g 100g⁻¹ of fat. Oleic acid may be used as a biomarker for the early diagnosis of elevated blood levels of NEFAs and BHBA in the early stages of lactation in high-yielding PHF cows.

11

Wild type root cultures of Scutellaria barbata

51%

Wilczanska-Barska A. , Krauze-Baranowska M. , Majdan M. , Glod D.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2011

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tom 92

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nr 4

12

Ekologiczny aspekt biofilmu w systemie dystrybucji wody do picia

51%

Biedroń I. , Traczewska T. M.

Instal

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2016

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tom nr 2

46--49

PL

Błona biologiczna to dynamiczna struktura składająca się z mikroorganizmów, wydzielanych przez nie wielkocząsteczkowych substancji polimerowych (peptydy, polisacharydy) oraz innych substancji zawieszonych w macierzy zewnątrzkomórkowej. Obecność biofilmu zwiększa koszty utrzymania sieci dystrybucji wody do picia, a badania nad tą strukturą nie są łatwe ze względu na trudny dostęp do próbek. Z punktu widzenia nauk przyrodniczych na błonę biologiczną należy patrzeć jak na spójną całość, która w wielu przypadkach funkcjonuje jak dojrzały ekosystem. Jest to zupełnie nowe podejście w mikrobiologii, dlatego też uzasadnione jest w tym przypadku stosowanie nowoczesnych technik badawczych, jaką jest system BIOLOG OmniLog.

EN

Biofilm is a dynamic structure consisting of microorganisms, their exopolymeric substances (peptides, polysaccharides) and other suspended substances in the extracellular matrix. The presence of biofilm increases the costs of maintaining the drinking water distribution system and also research on this structure are difficult because of the poor access to the samples. From the point of view of natural science the biofilm should be viewed as a coherent whole, which in many cases is functioning as a mature ecosystem. This is a completely new approach in microbiology, it is therefore justified in this case, the use of modern research techniques, which is BIOLOG OmniLog system.

13

Transgeniczne ogorki z ekspresja genu taumatyny II i ich akceptacja przez szkodniki

51%

Kielkiewicz M. , Szwacka M. , Gajc-Wolska J. , Malepszy S.

Zeszyty Problemowe Postępów Nauk Rolniczych

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2006

|

tom 509

395-404

PL

Prześledzono, czy w wyniku wprowadzenia genu taumatyny II do genomu ogórka, uzyskane linie wykazują zmieniony w stosunku do formy wyjściowej poziom atrakcyjności dla szkodników. Materiał roślinny stanowiły transgeniczne linie ogórka o zróżnicowanym poziomie taumatyny II (T224, T212, T210), pochodzące z trzech niezależnych zdarzeń transformacyjnych. Kontrolą była forma wyjściowa dla linii transgenicznych - wysoce wsobna linia wyprowadzona z odmiany Borszczagowski, określona jako linia B. Badania wykazały, że zarówno owady (mszyce i wciornastki) jak i roztocze (przędziorki) lokowały się na transgenicznych i nietransgenicznych liniach ogórka. Najwyższe liczebności szkodników odnotowano na przełomie czerwca i lipca. Mszyce i wciornastki zasiedliły słabiej te linie ogórka, których liście cechowała wysoka zawartość taumatyny II (T224 i T212). W tym czasie roztocze (przędziorki) skolonizowały tylko linie T224 i T212, a na liniach nietransgenicznych pojawiły się dopiero pod koniec sezonu. Na roślinach wszystkich badanych linii ogórka stwierdzono obecność naturalnego wroga mszyc - roztocza z rodziny Trombidiidae. Liście linii T212 wyróżniały się wysoką zawartością metabolitów podstawowych, ważnych w diecie szkodników. Kumulacja taumatyny II zwiększyła się wraz z wiekiem liści, natomiast stężenie metabolitów wtórnych (fenole ogólne) uległo obniżeniu. Wprowadzenie do genomu ogórka genu taumatyny II wpłynęło na ilościowe zmiany w poziomie akumulacji badanych metabolitów podstawowych i wtórnych, co w konsekwencji mogło modyfikować atrakcyjność transgenicznych roślin dla szkodników.

EN

The aim of the present work was to determine if thaumatin II gene insertion into the cucumber genome can change the chemical composition of transgenics plant affecting insect and mite-pests bahaviour and development. The attractiveness of 3 lines of transgenic cucumber plants (T224, T212, T210) and the highly inbred cucumber line B (parental line) to pests was evaluated under the field conditions. Additionally, the level of thaumatin II, leaf nutritional value (total nitrogen, soluble proteins, reducing sugars) and the level of secondary metabolites (total phenolics) in age-different leaves of transformed and untransformed plants were analysed. The study shows that significantly less aphids and thrips settled on the transgenic lines than on the line B. In contrast, at the beginning of season higher numbers of mite-pests were recorded on the transgenic lines as compared to non-trangenic ones. It was found that the transgene expression levels vary with leaf age: more thaumatin II was detected in fully expanded mature leaves as compared to young ones. A significantly higher concentration of total nitrogen, reducing sugars and total phenolics was found in young leaves of the T212 as compared to young leaves of other lines. Chemical composition of mature leaves of the T212 line differed significantly in the level of reducing sugars, soluble proteins and total phenolics as compared to leaves of others lines. Conclusion: In consequence of thaumatin II gene insertion into cucumber genome the production of some leaf metabolites important for pests changed making the transformed lines rather less attractive than untransformed ones to some sucking-pests as thrips and aphids.

14

Identification of risk factors for metritis in primiparous dairy cows

51%

Markiewicz H. , Zbylut J. , Malinowski E.

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2010

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tom 54

|

nr 4

EN

The objeclive of this study was to determine whether changes of biochemical indicators and T lymphocyte subpopulations during the prepartum period would differ between primiparous dairy cows that developed clinical metritis after calving and those that remained healthy. Cows that developed clinical metritis (53.3%) showed significant differences in age of the first calving and yield of milk during the first month of lactation. Clinical metritis in primiparous dairy cows was not connected with metabolic changes before parturition. Lower percentage of CD2+, CD4+, and CD8+ in metritic cows may be linked to the immunosuppression observed in periparturient cows.

15

Effect of concentrate feeding before calving on feed intake, metabolic profile and performance of early lactation cows

51%

Strzetelski J. A. , Osieglowski S. , Dymnicka M.

Annals of Animal Science

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2010

|

tom 10

|

nr 2

139-155

16

Values of selected biochemical parameters of cows’ blood during their drying-off and the beginning of lactation

51%

Kupczynski R. , Chudoba-Drozdowska B.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

|

2002

|

tom 05

|

nr 1

17

Badanie wskaznikow profilu metabolicznego i wartosci biochemicznych krwi i moczu nutrii

51%

Barabasz B. , Brytan I.

Acta Scientiarum Polonorum. Zootechnica

|

2003

|

tom 02

|

nr 2

19-24

18

Genetyczne aspekty odpornosci siarowej i profilu metabolicznego krwi u nowonarodzonych cielat

51%

Skrzypek R. , Jarmuz W. , Bialon K.

|

2006

|

tom 05

|

nr 2

107-117

19

Influence of pre- and postpartum supplementation of fibrolytic enzymes and yeast culture, or both, on performance and metabolic status dairy cows

51%

Lopuszanska-Rusek M. , Bilik K.

Annals of Animal Science

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2011

|

tom 11

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nr 4

20

Effects of different starch sources on metabolic profile, production and fertility parameters in dairy cows

51%

Mikula R. , Nowak W. , Jaskowski J. , Mackowiak P. , Pruszynska Oszmalek E.

Polish Journal of Veterinary Sciences

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2011

|

tom 14

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nr 1

EN

The objective of the study was to determine the effect of replacing triticale (high rumen degradable starch) with maize grain (low rumen degradable starch) during the transition period and the first 120 days of lactation on metabolic and hormonal profile indices, milk production and fertility performance in cows. Forty-eight Holstein-Friesian dairy cows were divided into 4 groups: TT (2.5 kg triticale grain/cow per day supplemented from 14 days prepartum to day 120 postpartum), TM (2.5 kg triticale grain/cow per day supplemented from day 14 before parturition to calving, and then 2.5 kg maize grain to 120 days of lactation), MT (2.5 kg maize grain/cow per day supplemented from day 14 before parturition to calving, and then 2.5 kg triticale grain to 120 days of lactation), MM (2.5 kg maize grain/cow per day supplemented from 14 days prepartum to day 120 postpartum). Blood samples were collected 3 weeks and 1 week before calving and on days 14, 56 and 70 of lactation, and they were analyzed in terms of concentrations of glucose, insulin, leptin, insulin-like growth factor I, nonesterified fatty acids, triglycerides, cholesterol, blood urea nitrogen and activities of aspartate aminotransferase and gamma glutamyl transpeptidase. Milk samples were collected twice a day at weekly intervals and analyzed for fat, protein and lactose. Milk yield and individual dry mater intake were recorded at weekly intervals. Body condition was estimated 3 weeks before calving, on parturition day and on days 14, 56 and 120 of lactation. Replacing triticale grain with maize grain in the transition period and during lactation positively affected fertility of lactating cows. An increased first service conception rate and shortening of the days open period was observed in MM and TM groups in comparison to those found in group MT (P ≤ 0.05). The lowest number of services per conception was recorded in groups MM and TM (P ≤ 0.05). Although the impact of milk production and the most of the blood indices were not significantly affected by this treatment, the results of the study suggest that maize grain in the transition period and lactation might be a more effective energy source for dairy cows than triticale grain.