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Celevaja mekhanoaktivacija metallokompozitov kak sredstvo modifikacii bazovogo syr'ja mim-tekhnologii

100%

Solenaja E. , Yanovich V.

Motrol. Motoryzacja i Energetyka Rolnictwa

2016

tom 18

nr 4

Vlijanie mekhaoaktivacii dobavki mikrokremnezema na struktury i svojjstva pressovannykh materialov iz granodioritovykh shlamov sharkinskogo kar'era

84%

El'kina I.

Motrol. Motoryzacja i Energetyka Rolnictwa

2013

tom 15

nr 5

Testing an influence of the piston mass and height on the vibrations dynamics in the cylinder liner of an agricultural tractor in proecological aspect

84%

Burski Z. , Tarasinska J.

Teka Komisji Motoryzacji i Energetyki Rolnictwa

2005

tom 05

Electrical activity of canine gallbladder

84%

Konturek J. W. , Scott G. W. , Kingma Y. J.

Journal of Physiology and Pharmacology

1991

tom 42

nr 1

Our aims were to describe the myoelectrical activity in the single very thin layer of muscle of the canine gallbladder. The study was performed on 22 freshly removed canine gallbladders. Electrical activity was studied by the single sucrose-gap method and contractility of the tissue was measured simultaneously using a force transducer. The strips (15x1 mm) from different regions of gallbladder (fundus, corpus, neck) were cut in longitudinal, circular and oblique axes. The sucrose-gap apparatus together with connecting tubes, solutions and electrodes were kept at 37°C and the initial tension applied to the tissue was set to 1 g. In 82.7% of recordings, spontaneous myoelectrical activity consisted of regular rhythmic changes in membrane potential similar to slow waves recorded in intestinal tissue. The overall mean frequency was 11.4 ± 5.2 (mean ±SD) cycles per min: 11.1 ± 4.4 cycles per min in fundus, 11.9 ± 6.2 cycles per min in corpus and 10.8 ± 3.8 cycles per min in the neck of the gallbladder. In 84.2% of cases electrical activity correlated with mechanical activity and preceded it. No significant differences were seen between the electrical patterns in strips with different orientations or from the different regions of the gallbladder.

Papaverine should not be used as an indicator for controlling the ability of the gastrointestinal tract muscle to relax in vitro

67%

Chlopecka M. , Dziekan N. , Bakala A. , Wiechetek M. , Mendel M.

tom 63

nr 11 Supl.

1437-1439

The aim of this research was to study the possibilities of using papaverine as a reference substance to control the ability of isolated gastrointestinal (GI) tract strips to relax. The effects of papaverine hydrochloride (0.001-100 µM) dissolved in distilled water, or in DMSO (0.5%), on the mechanical activity of isolated rat GI strips (stomach fundus and corpus, duodenum and jejunum) were studied. The obtained results show that papaverine provoked various responses of the examined muscle strips dependent on the part of GI tract and papaverine solvents used (water or DMSO). Papaverine applied as water solution caused muscle relaxation of all investigated gastrointestinal strips: the lowest effective (induced relaxation) concentration of papaverine was 10 µM for gastric corpus, jejunum and duodenum and 100 µM for gastric fundus. However, there was no dependence between the concentration of papaverine and the degree of muscle relaxation of the studied GI strips. Moreover, in case of gastric fundus strips, papaverine applied as 0.5% DMSO solution provoked different muscle responses: in the presence of 0.1 and 1 µM papaverine contraction occurred; administering papaverine at higher concentrations (10 and 100 µM) resulted in relaxation. The obtained results clearly indicate that papaverine does not fulfil the criteria set for the reference substance and should not be used as an indicator for controlling of gastrointestinal tract muscle relaxation in vitro.