Wyniki wyszukiwania - Biblioteka Nauki

1

Juvenile nasopharyngeal angiofibroma with intracranial extension – diagnosis and treatment

100%

Gołąbek W. , Szymańska A. , Szymański M. , Czekajska-Chehab E. , Jargiełło T.

Otolaryngologia Polska

|

2020

|

tom 74(2)

1-7

EN

Introduction: This retrospective study analyzes radiological findings, therapeutic management and outcomes of patients with intracranial extension of JNA. The routes of intracranial spread, incidence of intracranial disease and influence on therapeutic approach are discussed. Material and methods: An evaluation on the records of 62 patients with JNA was performed and 10 patients with intracranial tumors were included in the study. All patients were males aged 10 to 19 years. R esults: According to Andrews’ classification 8 patients presented with stage IIIb, 1 patient stage IVa and another patient stage IVb tumor. Intracranial invasion was extradural in 8 cases and intradural in 2 patient. Surgery was performed in 9 cases and the most common was combined approach: infratemporal fossa and sublabial transantral. One patient was referred for radiotherapy. Follow-up ranged from 8 to 26 years. There was extracranial recurrence in 2 (22%) of 9 operated patients. C onclusions: The superior orbital fissure is the most frequent route of intracranial spread in patients with extensive involvement of the infratemporal fossa. Due to high risk of recurrence and potential serious complications advanced cases of JNA should be managed by experienced multidisciplinary team, preferably in tertiary referral centers, with an access to modern diagnostic and therapeutic modalities.

2

A new approach to define surface/sub-surface transition in gravel beds

100%

Haynes H. , Ockelford A.-M. , Vignaga E. , Holmes W.

Acta Geophysica

|

2012

|

tom Vol. 60, no. 6

1589-1606

EN

The vertical structure of river beds varies temporally and spatially in response to hydraulic regime, sediment mobility, grain size distribution and faunal interaction. Implicit are changes to the active layer depth and bed porosity, both critical in describing processes such as armour layer development, surface-subsurface exchange processes and siltation/sealing. Whilst measurements of the bed surface are increasingly informed by quantitative and spatial measurement techniques (e.g., laser displacement scanning), material opacity has precluded the full 3D bed structure analysis required to accurately define the surface-subsurface transition. To overcome this problem, this paper provides magnetic resonance imaging (MRI) data of vertical bed porosity profiles. Uniform and bimodal (σg = 2.1) sand-gravel beds are considered following restructuring under sub-threshold flow durations of 60 and 960 minutes. MRI data are compared to traditional 2.5D laser displacement scans and six robust definitions of the surface-subsurface transition are provided; these form the focus of discussion.

3

State of art of MRI of fetal heart

100%

Manganaro L.

Prenatal Cardiology

|

2015

|

tom 5

|

nr 3

9-12

EN

Congenital heart defect (CHD) is one of the most common type of fetal malformations. Tissue-Doppler imaging, dynamic threedimensional (4D) echocardiography and fetal cardiac magnetic resonance imaging (MRI) are advanced modalities for the assessment of cardiac structure and function. MRI can study the cardiac morphology using T2-weighted half-Fourier single-shot turbo spin-echo sequence (HASTE) and steady-state free precession (True FISP) sequences. Also a dynamic study can be performed, through the acquisition of cine-MR sequences with real-time steady-state free precession (SSFP) oriented according to the standard projections used in fetal echocardiographic scanning. If the challenges relating to motion and cardiac gating can be overcome, MRI has the potential to provide high-resolution imaging of the fetal heart.

4

Least squares support vector machine based classification of abnormalities in brain MR images

100%

Selvi S. , Selvathi D. , Ramkumar R. , Selvaraj H.

|

2006

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tom Vol. 32, no 1

89-103

EN

The manual interpretation of MRI slices based on visual examination by radiologist/physician may lead to missing diagnosis when a large number of MRJs arc analyzed. To avoid the human error, an automated intelligent classification system is proposed. This research paper proposes an intelligent classification technique to the problem of classifying four types of brain abnormalities viz. Metastases, Meningiomas, Gliomas, and Astrocytomas. The abnormalities are classified based on Two/Three/ Four class classification using statistical and texlural features. In this work, classification techniques based on Least Squares Support Vector Machine (LS-SVM) using textural features computed from the MR images of patient are developed. LS-SVM classifier using non-linear radial basis function (RBF) kernels is compared with other techniques such as SVM classifier and K-Ncarest Neighbor (K-NN) classifier. It has been observed that the method proposed using LS-SVM classifier outperforms all the other classifiers tested.

5

MRI as a potential tool for monitoring of therapeutic monoclonal antibody distribution in cancer patients

100%

Tabarkiewicz J. , Aebisher D. , Bartusik-Aebisher D.

Acta Poloniae Pharmaceutica - Drug Research

|

2020

|

tom 77

|

nr 3

383-389

EN

Imaging and quantification of MAbs distribution by MRI after administration in vivo can improve patient outcomes, although it is not routinely used in the clinic hence the motivation for development of new MAbs imaging methodologies. Improvements in imaging and quantification of antibody distributions can be made by conjugating MAbs to “hotspot” atoms such as 19F as 19F Currently, research investigating the incorporation of 19F to antibody delivery systems has been limited to trastuzumab perfluorocarbon emulsions and this method has not been extended to other clinically approved antibodies. The methodologies of 19F MRI can improve current limitations of antibody immunotherapy such as quantitative visualization of targeted surface antigens expressed on tumor cells.

6

19F MRI As a tool for imaging drug delivery to tissue and individual cells

100%

Zuzanna Bober Z. , David Aebisher D. , Łukasz Ożóg Ł. , Jacek Tabarkiewicz J. , Piotr Tutka P. , Dorota Bartusik-Aebisher D.

European Journal of Clinical and Experimental Medicine

|

2017

|

nr 2

99-109

EN

Over the past few decades, magnetic resonance imaging (MRI) has proven to be extremely successful in medical applications. More recently, the biomedical applications of MRI have been gaining more use in the field of clinical pharmacy. In 1977, perfluorocarbon compounds (PFC), which form emulsions that can carry drugs, were analyzed by 19F MRI and emulsified PFC compounds have been investigated as potential blood substitutes since the early 1960s and now a wide variety of PFC compounds are currently available as 19F MRI biomarkers. Molecules with 19F substituents are particularly attractive for use in drug tracking by 19F MRI due to 100% 19F abundance, high 19F MRI sensitivity (0.83 relative to 1H MRI) and an impressively large chemical shift range (400 ppm). Another benefit in the use of 19F MRI is a zero background signal in biological samples due to lack of endogenous fluorine. Therefore, drugs containing fluorine atom have potential for 19F MRI imaging drug delivery to tissue. This article will review recent developments in the use of 19F MRI in imaging drug delivery to tissue and individual cells.

7

A novel technique to evaluate the geometrical accuracy of CT-MR image fusion in Gamma Knife radiosurgery procedures

100%

Thomas S. , Sampath S. , IndiraDevi B. , Bhanumathy G. , Supe S. , Musthafa M.

Polish Journal of Medical Physics And Engineering

|

2010

|

tom 16

|

nr 2

55-66

EN

In order to optimize the accuracy of imaging in Gamma Knife radiosurgery using the image fusion options available in the Leksell gamma plan. Phantom images from 1.5 Tesla MRI Scan (Magnetom vision - Siemens) and Computed Tomography images from Philips Brilliance 16 CT scanner were used for image fusion in Gammaplan treatment planning system. The images were fused using co-registration technique using multiview and imagemerge modules. Stereotactic coordinates were then calculated for known targets. Vector distances from the centre of the Leksell coordinate system to five known targets were measured in CT, MR and CT-MR fused images and compared with geometrical measurements. The mean values of maximum absolute errors were 0.34 mm, 0.41 mm.0.38 mm (along x-axis), 0.43 mm, 1.53 mm, 0.62 mm (along y-axis) and 0.75 mm 2.02 mm, 0.93 mm (along z-axis) for CT, MR and CT-MR fused image data respectively. The mean error in calculating the vector distances from the center of the Leksell coordinate system (100, 100, 100) to the known target volumes are 0.22 mm, 0.8 mm and 0.43 mm for CT, MR and CT-MR fused images, respectively. Image fusion functions available in gamma plan are useful for combining the features of CT and MR imaging modalities. These methods are highly useful in clinical situations where the error associated with Magnetic Resonance Imaging is beyond acceptable levels.

8

Magnetic Resonance Elastography – noninvasive method to assess liver disease

100%

Łukasz Ożóg Ł. , David Aebisher D. , Zuzanna Bober Z. , Dorota Bartusik-Aebisher D. , Wiesław Guz W. , Marian Cholewa M.

European Journal of Clinical and Experimental Medicine

|

2017

|

nr 2

127-132

EN

Currently, liver disease is widespread and the awareness of these diseases is low. Early symptoms of liver disease do not necessarily indicate problems with this organ and patients are usually informed of their problems when the stage of the disease is already advanced. Invasive biopsies are the clinical diagnostic method most commonly used in the evaluation of liver disease. A biopsy is associated with a high risk of false results and additional complications. Finding new non-invasive imaging methods has led to the discovery of a new method called Magnetic Resonance Elastography (MRE). This technique allows one to evaluate the mechanical properties of tissues and to distinguish between pathological states. Testing using this technique can be performed on a conventional magnetic resonance system by using few additional components and properly prepared software. Studies have shown that there is a strong correlation between MRE-measured liver stiffness and the degree of fibrosis. MRE is also useful in characterizing liver tumors. Studies show that this technique is highly credible in both health volunteers and patients with liver fibrosis. MRE has tremendous diagnostic potential. The described technique is not currently widely used and has the 127-132potential to serve as a safe and accurate alternative in clinical diagnostics in the future.

9

Juvenile nasopharyngeal angiofibroma with intracranial extension – diagnosis and treatment

100%

Gołąbek W. , Szymańska A. , Szymański M. , Czekajska-Chehab E. , Jargiełło T.

Polish Journal of Otolaryngology

|

2020

|

tom 74

|

nr 2

1-7

EN

Introduction: This retrospective study analyzes radiological findings, therapeutic management and outcomes of patients with intracranial extension of JNA. The routes of intracranial spread, incidence of intracranial disease and influence on therapeutic approach are discussed. Material and methods: An evaluation on the records of 62 patients with JNA was performed and 10 patients with intracranial tumors were included in the study. All patients were males aged 10 to 19 years. R esults: According to Andrews’ classification 8 patients presented with stage IIIb, 1 patient stage IVa and another patient stage IVb tumor. Intracranial invasion was extradural in 8 cases and intradural in 2 patient. Surgery was performed in 9 cases and the most common was combined approach: infratemporal fossa and sublabial transantral. One patient was referred for radiotherapy. Follow-up ranged from 8 to 26 years. There was extracranial recurrence in 2 (22%) of 9 operated patients. C onclusions: The superior orbital fissure is the most frequent route of intracranial spread in patients with extensive involvement of the infratemporal fossa. Due to high risk of recurrence and potential serious complications advanced cases of JNA should be managed by experienced multidisciplinary team, preferably in tertiary referral centers, with an access to modern diagnostic and therapeutic modalities.

10

Trastuzumab Efficacy Quantified by Fluorine-19 Magnetic Resonance Imaging

88%

Bartusik-Aebisher D. , Aebisher D. , Czmil M. A. , Mazur D.

Acta Poloniae Pharmaceutica - Drug Research

|

2020

|

tom 77

|

nr 3

495-503

EN

The purpose of this study was to conjugate Trastuzumab with fluorine-bearing PAMAM dendrimer to compare activities in three-dimensional (3D) cultured breast cancer cells with parent Trastuzumab. An in vitro study was performed to determine cellular responses to fluorinated Trastuzumab conjugates by Magnetic Resonance Imaging (MRI). Breast cancer cells were cultured in 3D geometry. Proton (1H) MRI and Fluorine-19 (19F) MRI were used for visualization of cellular locations within a Hollow Fiber Bioreactor (HFBR) device and to monitor the cellular response to treatment. The results of this study confirm that cell growth is significantly decreased following treatment with Trastuzumab conjugates. The use of fluorinated Trastuzumab conjugates decreases breast cancer cell growth in 3D cultures and allows for tracking of drug delivery to cancer cells via 19F.

11

Contrast-enhanced Magnetic Resonance Imaging of lung cell cultures

88%

Bober Z. , Pogoda K. , Aebisher D. , Tabarkiewcz J. , Bartusik-Aebisher D.

Acta Poloniae Pharmaceutica - Drug Research

|

2020

|

tom 77

|

nr 2

251-258

EN

Lung cancer is one of the most common types of cancer diagnosed, and the development of methods to image diseased lung tissue by MRI is of utmost importance. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) was used to noninvasively evaluate spin-spin relaxation time, T1, of lung cell cultures infused with various clinical gadolinium-based contrast media for imaging. In this study we used a clinical 1.5 Tesla scanner and the contrast agents: Omniscan, MultiHance, Gadovist and ProHance. A significant five-fold reduction of T1 relaxation time was obtained.

12

Magnetic resonance imaging of the inner ear in the diagnostics of Ménière’s disease

75%

Jasińska A. , Lachowska M. , Wnuk E. , Niemczyk K.

Polish Journal of Otolaryngology

|

2021

|

tom 75

|

nr 2

1-8

EN

Ménière’s disease is characterized by sudden episodes of vertigo accompanied by tinnitus and/or feeling of fullness in the ear as well as fluctuating sensorineural hearing loss. Despite numerous studies, the etiology of this disease remains unknown. However, the enlargement of the inner ear’s endolymphatic spaces, referred to as endolymphatic hydrops, is considered the underlying condition. Thanks to recent advances in magnetic resonance (MR) technology, it is now possible to obtain in vivo imaging of endolymphatic hydrops in patients presenting with Ménière’s disease symptoms. Visualization of the inner ear fluid compartments is achieved after gadolinium contrast is administered into the tympanic cavity or via the intravenous route. Evaluation of endolymphatic hydrops is possible as the contrast agent selectively penetrates the perilymph, and endolymph is visualized as contrast defects. The currently used radiological hydrops grading systems include qualitative, semi-quantitative, and volumetric scales. The methods are subject to ongoing modifications to increase their sensitivity and specificity. Numerous studies describe correlations between clinical symptoms and audiological and otoneurological examination results with the endolymphatic hydrops grade. MRI is also applicable in patients’ diagnostics with an incomplete or atypical course of the Ménière’s disease. In the course of the treatment, follow-up MRI scans enable assessing individual treatment modalities’ efficacy in terms of the severity of lesions and the further course of the disease within the inner ear.

13

Magnetic resonance imaging of the inner ear in the diagnostics of Ménière’s disease

75%

Jasińska A. , Lachowska M. , Wnuk E. , Niemczyk K.

Otolaryngologia Polska

|

2021

|

tom 75(2)

1-8

EN

Ménière’s disease is characterized by sudden episodes of vertigo accompanied by tinnitus and/or feeling of fullness in the ear as well as fluctuating sensorineural hearing loss. Despite numerous studies, the etiology of this disease remains unknown. However, the enlargement of the inner ear’s endolymphatic spaces, referred to as endolymphatic hydrops, is considered the underlying condition. Thanks to recent advances in magnetic resonance (MR) technology, it is now possible to obtain in vivo imaging of endolymphatic hydrops in patients presenting with Ménière’s disease symptoms. Visualization of the inner ear fluid compartments is achieved after gadolinium contrast is administered into the tympanic cavity or via the intravenous route. Evaluation of endolymphatic hydrops is possible as the contrast agent selectively penetrates the perilymph, and endolymph is visualized as contrast defects. The currently used radiological hydrops grading systems include qualitative, semi-quantitative, and volumetric scales. The methods are subject to ongoing modifications to increase their sensitivity and specificity. Numerous studies describe correlations between clinical symptoms and audiological and otoneurological examination results with the endolymphatic hydrops grade. MRI is also applicable in patients’ diagnostics with an incomplete or atypical course of the Ménière’s disease. In the course of the treatment, follow-up MRI scans enable assessing individual treatment modalities’ efficacy in terms of the severity of lesions and the further course of the disease within the inner ear.

14

Klimatyzacja - wentylacja pomieszczeń angiografii i rezonansu magnetycznego

75%

Kaiser K.

|

2011

|

tom nr 6-7

307-310

PL

Artykuł jest próbą wypełnienia istniejące} w Polsce luki informacyjnej, dotyczącej klimatyzacji i wentylacji pomieszczeń, w których wykonuje się badania angiograficzne i rezonansowe. W opracowaniu zawarte zostały zalecenia autora, oparte o jego doświadczenia praktyczne, jakie powinna spełniać instalacja klimatyzacji i wentylacji, aby zapewnić osiąganie i utrzymanie odpowiednich parametrów fizycznych powietrza oraz właściwą jego czystość w tego typu pomieszczeniach

EN

In polish professional literature there is a lack of information on ventilation of rooms for angiography and magnetic resonance. This temp of completion some useful data about required air parameters and purity for such objects. Based on Author's experience, reclitions for such plants are included in the paper

15

Problemy diagnostyczne w przebiegu leczenia podwójnej macicy – opis przypadku

75%

Raba G.

Medical Review

|

2013

|

nr 2

252–256

PL

Macica podwójna stanowi rzadką postać malformacji macicy, powstającą na skutek całkowitego niezrośnięcia się przewodów Müllera. Dzięki dostępności licznych badań obrazowych jej diagnostyka na ogół nie stwarza problemów klinicznych. Przyjmuje się, że w rozpoznaniu podwójnej macicy pomocne są: ultrasonografia przezpochwowa, sonohisterografia, histerosalpingografia, rezonans magnetyczny, histeroskopia, oraz 3-D USG. W pracy przedstawiono opis przypadku krwiaka w niedrożnym trzonie macicy prawej imitującego torbiel endometrialną. Prezentowany opis przypadku dowodzi, że w szczególnych stanach klinicznych rozpoznanie podwójnej macicy może być trudne, a nowoczesne techniki obrazowania są jedynie badaniami dodatkowymi, które pomagają w ustaleniu rozpoznania, lecz nie mogą samodzielnie o nim stanowić.

EN

Double uterus is a rare form of uterine malformation resulting from an incomplete fusion of the Müllerian ducts. Thanks to availability of numerous imaging tests its diagnostics in general does not present clinical problems. It is assumed that in the diagnosis of double uterus the following examinations can be helpful: transvaginal ultrasonography, sonohysterography, hysterosalpingography, magnetic resonance imaging, hysteroscopy, and 3D Ultrasound. The presented case report has proved that in certain clinical states the diagnosis of double uterus can be difficult, and the modern imaging techniques are only additional examinations, which can help to make a diagnosis but cannot establish it on their own.

16

Virtual magnetic resonance imaging - parallel implementation in a cluster computing environment

75%

Jurczuk K. , Krętowski M.

|

tom Vol. 29, no. 3

31-46

EN

In this paper, we present a virtual scanner of magnetic resonance imaging that aims at simplifying and accelerating methods of generating images. After an introduction to the subject of nuclear magnetic resonance and various approaches to the simulation of magnetic resonance imaging, details of the simulator are described. The proposed simulator consists of magnetization kernel (based on a solution of the Bloch equation), graphical user interface and module that performs calculation in a parallel environment. The package which parallelizes the magnetic resonance simulation is implemented on a computing cluster with the use of the Message Passing Interface standard. The parallel module can divide calculations related to different slices or different phase encoding steps between processors. The experimental results in the parallel environment show that it is possible to gain a significant speedup thus making it possible to acquire more exact images in a reasonable period of time.

17

Viscoelastic changes in the blood and vascular wall in a pulsating circular flow

75%

Beraia M. , Todua F. , Khomeriki I.

Polish Journal of Medical Physics And Engineering

|

2010

|

tom 16

|

nr 1

43-53

EN

Altered flow conditions, such as separation and recirculationg zones, low and oscillatory shear stress, play an important role in the development of arterial disease. Endothelial denudation by the blood flow is the first step in atherosclerosis. The description of blood flow in vivo is complicated due to the viscoelasticity of vessel walls. However, conventional researches of the effect of the blood vessel viscoelasticity on the blood pressure wave propagation using non-linear one-dimensional models do not take into account the viscoelasticity, despite it being importance in the analysis of pulse wave propagation in arteries.The purpose of this paper is to study the impact of the arterial pulse wave on the viscoelastic blood flow and initial factors of atherosclerosis.In 12 healthy men (25-39 years of age) peak velocity, mean velocity, mean flow and net flow in the aorta have been investigated by MR angiography.Initial velocity was registered after 43msec of the ECG-R wave, and it differed from zero at all sites of the aorta, although net flow was equal to zero. Womersley's number from the ascending to the thoracic aorta decreased from 12.5 ± 1.5 to 7.3 ± 1.2; flow modified from inertio-elastic to viscous. Pulse pressure wave move on artery walls fifteen or more times more rapidly than the blood flow. In the aortic arch in protodiastole blood flow separated into the opposite directed streams resulting in wave superposition with the high net flow. At the isthmus area separated waves interferences and reflects to anterograde direction.Pulse oscillation increases strain rate to the contiguous vessel wall flow layers. At the sites with the flow wave negative interference vessel pulse oscillation attenuates and at the boundary reflection flow wave can shift the vessel wall.

18

Magnetic resonance imaging of electric properties in living bodies

63%

Sekino M. , Ueno S.

|

tom Vol. 27, no. 1-2

177-184

EN

New methods for magnetic resonance imaging of electric properties in living bodies have been developed. The method of conductivity imaging was based on the proportionality between the electric conductivity and the diffusion coefficient of water. The conductivity images of the human brain exhibited high anisotropy in conductivity in some regions in the white matter. A distinctive signal inhomogeneity arises in the magnetic resonance images of samples whose dimension is comparable to the wavelength of RF electromagnetic fields. Spatial distributions of the magnitude and phase in cylindrical phantoms were obtained by theoretical calculations and experiments at 4.7 T. As the diameter of the phantom approaches to the wavelength of the electromagnetic fields in the phantom, the magnitude of the signals in the center increases because of the dielectric resonance effect. An increase in conductivity resulted in a suppression of the signal inhomogeneity due to the skin effect. In addition, the increase in conductivity caused a phase delay in the center of the phantom.

19

Ciąża i poród u chorych na stwardnienie rozsiane

63%

Czernichowska-Kotiuszko M. , Bartosik-Psujek H.

Aktualności Neurologiczne

|

2014

|

tom 14

|

nr 1

25-29

EN

Multiple sclerosis (MS) is the main cause of disability in young adults and, as most autoimmune diseases, more commonly affects women. The relationship between pregnancy and MS has been an issue of significance for many years and has recently become the subject of multicentre studies. Usually, pregnancy is a period of relative wellness for patients and most commonly is a period without relapse. This boost of health involves the change of immune reactivity to anti-inflammation associated with Th2 lymphocytes and anti-inflammatory cytokines (interleukin 4, 5, 6, 10, TGF-β). After giving birth, a woman’s immune system returns to its original level of activity and disease susceptibility increases. Most studies have shown no overall negative impact of pregnancy on longterm disability associated with MS, and MS does not have negative impacts on pregnancy, childbirth or the child’s condition. Women with MS can plan to have children. The disease does not increase the risk of pregnancy/ childbirth complications or birth defects compared to the general population. Each immunomodulatory therapy is contraindicated in pregnancy. If a patient wishes to become pregnant, discontinuation of the therapy much before planned pregnancy is recommended. The work summarizes available information on clinical problems associated with pregnancy and childbirth in patients with MS and analyses risks to the child associated with the administration of drugs.

PL

Stwardnienie rozsiane (łac. sclerosis multiplex, SM) jest główną przyczyną niepełnosprawności u młodych dorosłych i jak większość chorób autoimmunologicznych częściej dotyczy kobiet. Wpływ ciąży na przebieg SM wzbudza zainteresowanie od wielu lat, a w ostatnim okresie stanowi temat badań wieloośrodkowych. Ciąża to zwykle okres bardzo dobrego samopoczucia chorych, najczęściej bez rzutów. Wynika to ze zmiany reaktywności immunologicznej na korzyść reakcji przeciwzapalnych związanych z limfocytami Th2 i cytokinami antyzapalnymi (interleukina 4, 5, 6, 10, TGF-β). Po porodzie zmienia się reaktywność immunologiczna i aktywność choroby wzrasta. Większość badań nie wykazała ogólnego negatywnego wpływu ciąży na niesprawność długoterminową związaną z SM; stwardnienie rozsiane nie ma negatywnego wpływu na przebieg ciąży, porodu i stan dziecka, dlatego chore kobiety mogą planować potomstwo. Choroba nie zwiększa ryzyka powikłań w ciąży i podczas porodu ani wad wrodzonych u dziecka w porównaniu z populacją ogólną. Jednakże każda terapia immunomodulująca jest przeciwwskazana w ciąży. Jeśli pacjentka decyduje się na dziecko, powinna przerwać leczenie; zaleca się również przerwę od leków przed zajściem w ciążę. W pracy podsumowano dostępne informacje na temat klinicznych problemów dotyczących ciąży i porodu u chorych na SM oraz oceniono zagrożenia dla dziecka związane z podawaniem leków.

20

Nowy ultrasonograficzny test przedniej niestabilności stawu kolanowego – doniesienie wstępne

63%

Grzelak P. , Podgórski M. , Stefańczyk L. , Domżalski M.

Journal of Ultrasonography

|

2014

|

tom 14

|

nr 58

252-257

EN

Aim of the study: Ultrasound examination is widely used in orthopedic diagnostics, however sonographic evaluation of traumatic anterior cruciate ligament insufficiency is still inadequate. Aim of this study is to evaluate diagnostic capability of a new sonographically- guided test for diagnosing complete anterior cruciate ligament insufficiency. Material and methods: In 47 patients, with suspicion of unilateral anterior cruciate ligament injury (based on magnetic resonance imaging), the sonographically-guided test for anterior instability was performed. The translation of the intercondylar eminence against the patellar tendon was measured in both knees. Afterwards all patients underwent arthroscopy. Results: In 37 patients, with arthroscopically confirmed complete anterior cruciate ligament insufficiency, the mean anterior knee translation was 8.3 mm (SD = 2.8) in affected knee vs. 3 mm (SD = 1.1) in uninjured knee (p < 0.001). In 10 patients with no anterior cruciate ligament insufficiency the difference between body sides was not significant (2.6 mm, SD = 1.4 in injured knee vs. 2.5 mm, SD = 1.1 in uninjured joint; p < 0.7753). Conclusions: The proposed test supports the clinician with fast and non- invasive examination that can facilitate evaluation of anterior knee instability.

PL

Cel pracy: Badanie ultrasonograficzne jest powszechnie stosowane w diagnostyce ortopedycznej, jednakże w ocenie przedniej niestabilności stawu kolanowego wykorzystuje się je w ograniczonym stopniu. Celem pracy jest ocena przydatności diagnostycznej nowego testu przeprowadzonego pod kontrolą ultrasonografii, który pomaga diagnozować całkowitą niewydolność więzadła krzyżowego przedniego. Materiał i metody: U 47 pacjentów z podejrzeniem jednostronnego urazu więzadła krzyżowego przedniego (zdiagnozowanego na podstawie badania rezonansu magnetycznego) wykonano test niestabilności przedniej kolana pod kontrolą ultrasonografii. Oceniano przesunięcie wyniosłości międzykłykciowej do przodu względem więzadła rzepki w obu stawach kolanowych. Każdy pacjent został następnie poddany artroskopii stawu kolanowego. Wyniki: U 37 pacjentów z artroskopowo potwierdzonym całkowitym uszkodzeniem więzadła krzyżowego przedniego średnie przesunięcie wyniosłości międzykłykciowej wynosiło 8,3 mm (SD = 2,8) w kolanach po urazie – w porównaniu z 3 mm (SD = 1,1) w kolanach bez urazu (p < 0,001). W grupie 10 pacjentów bez niewydolności więzadła krzyżowego przedniego różnice w przesunięciu wyniosłości międzykłykciowej były nieistotne (2,6 mm, SD = 1,4 w kolanie po urazie, w porównaniu z 2,5 mm i SD = 1,1 w kolanie bez urazu, p < 0,7753). Wnioski: Zaprezentowany test to szybki i nieinwazyjny sposób mogący ułatwić diagnozowanie całkowitej niewydolności więzadła krzyżowego przedniego.