Wyniki wyszukiwania - Biblioteka Nauki

1

Electron-dense deposits in epididymal cells of rats chronically treated with lead acetate [Pb II]

100%

Piasecka M. , Rozewicka L. , Laszczynska M. , Marchlewicz M.

Folia Histochemica et Cytobiologica

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1995

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tom 33

|

nr 2

2

Computerized analysis of cytochemical reactions of spermatozoa in rats chronically treated with lead acetate [ Pb[II] ]

100%

Piasecka M. , Wenda-Rozewicka L. , Kram A.

Folia Histochemica et Cytobiologica

|

1997

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tom 35

|

nr 2

3

Repeated administration of lead decreases brain 5-HT metabolism and produces memory deficits in rats

86%

Haider S. , Shameem S. , Ahmed S. P. , Perveen T. , Haleem D. J.

Cellular and Molecular Biology Letters

|

2005

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tom 10

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nr 4

4

Phospholipid content and lamellar structures in the epididymal epithelial cells of rats treated chronically with lead acetate [Pb[II]]

86%

Wiszniewska B. , Marchlewicz M. , Piasecka M. , Wenda-Rozewicka L. , Swider-Al-Amawi M.

Folia Biologica

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1998

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tom 46

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nr 3-4

5

Effects of vitamin C and magnesium L-threonate treatment on learning and memory in lead-poisoned mice

72%

Bislimi K. , Mazreku I. , Halili J. , Aliko V. , Sinani K. , Hoxha L.

Journal of Veterinary Research

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2021

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tom 65

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nr 2

6

Effect of lead acetate on mortality of entomopathogenic nematodes Heterorhabditis megidis (Poinar, Jackson and Klein 1987)

72%

Matuska J. , Kamionek M.

|

2005

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tom Vol. 12, nr 10

1101-1106

EN

The effect of lead acetate on mortality of the invasive larvae of Heterorhabditis megidis was studied in laboratory conditions. Larvae were kept in aquatic solutions of different concentrations of ions Pb(II) (40, 100,500, 1000 and 5000 ppm) at a temperature of 25 oC. Samples were collected and nematode mortality was studied every day during the 13 days of experiment. It was found that mortality depends on lead concentrations and on the time of larval contact with lead acetate. One hundred percent mortality was found at the highest lead concentration (5000 ppm) after four day exposition of larvae to lead ions. The results were compared with investigations performed earlier influence of lead nitrate(V) on invasive larvae Heterorhabditis megidis.

PL

W warunkach laboratoryjnych badano oddziaływanie octanu ołowiu na śmiertelność larw inwazyjnych Heterorhabditis megidis. Larwy przetrzymywano w roztworach wodnych zawierających różne stężenia jonów Pb(lI) (40, 100,500, 1000 i 5000 ppm), w temperaturze 25 oC. Jako kontrolę przyjęto larwy przetrzymywane w wodzie destylowanej. Codziennie przez 13 dni pobierano próbki i badano śmiertelność nicieni. Wykazano, że śmiertelność ich zależała od stężenia jonów ołowiu oraz czasu kontaktu z jonami. Stuprocentową śmiertelność, przy największym stężeniu octanu ołowiu (5000 ppm), stwierdzano po czterech dniach kontaktu larw z jonami ołowiu. Wyniki porównano z wcześniejszymi badaniami nad wpływem azotanu ołowiu na larwy inwazyjne Heterorhabditis megidis.

7

Histochemical changes in the testes of lead induced experimental rats

72%

Chowdhury A. R. , Rao R. V. , Gautam A. K.

Folia Histochemica et Cytobiologica

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1986

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tom 24

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nr 3

8

Ultrastructural alterations of the small intestine enterocytes in rats associated with lead acetate poisoning

72%

Tomczok J. , Sliwa W. , Grzybek H. , Panz B.

Folia Histochemica et Cytobiologica

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1986

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tom 24

|

nr 4

9

Combined activity of thiram and lead acetate in Salmonella typhimurium tester strains

72%

Czeczot H. , Zarnowiecka-Kokot A.

Acta Poloniae Toxicologica

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1996

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tom 04

|

nr 2

10

The influence of chelidonine and Ukrain on the beta-2-microglobulin concentration in the serum of lead-poisoned rats

72%

Jagiello-Wojtowicz E. , Maciejewska-Kozak H. , Chodkowska A. , Radej R.

Herba Polonica

|

2003

|

tom 49

|

nr 3-4

EN

The present study investigated the effects of single (lx) administration and a 10-day treatment with chelidonine (50 and 100 mg/kg i.p.) or drug Ukrain (7 and 14 mg/kg i.p.) on the ß2-microglobulin concentration in the serum of acute or subacute lead-poisoned rats (30 mg/kg i.p.). Both acute and subacute lead-intoxication significantly enhanced ß2- microglobulin concentration in the rats serum in comparison to the control groups. In acute poisoning only chelidonine (100 mg/kg i.p.) significantly decreased ß2-microgIo- bulin concentration in the rat serum. In subacute lead intoxication, 10-day treatment with chelidonine (50 mg/kg i.p.) or Ukrain (14 mg/kg i.p.) significantly decreased ß2- microglobulin in the serum of rats. Both chelidonine as well as Ukrain decreased nefrotoxicity induced by lead acetate. These investigations are to be continued.

PL

W pracy badano wpływ jednorazowego i 10-dniowego podawania chelidoniny (50 i 100 mg/kg i.p.) oraz leku Ukrain (7 i 14 mg/kg i.p.) na stężenie ß2-mikroglobuliny w surowicy krwi szczurów w ostrym i podostrym zatruciu octanem ołowiu (30 mg/kg i.p.) Zarówno ostre, jak i podostre zatrucie ołowiem, powodowało istotny wzrost stężenia ß2-mikro- globuliny w surowicy szczurów w porównaniu z grupą kontrolną. U szczurów poddanych ostremu zatruciu ołowiem tylko chelidonina (100 mg/kg i.p.) istotnie obniżała stężenie P2-mikroglobuliny w surowicy krwi. 10-dniowe podanie chelidoniny (50 mg/kg i.p.) lub leku Ukrain (14 mg/kg i.p.) istotnie zmniejszało stężenie ß2-mikroglobuliny w surowicy zwierząt poddanych podostremu zatruciu ołowiem. Zarówno chelidonina, jak też lek Ukrain, zmniejszały nefrotoksyczność indukowaną ołowiem. Badania będą kontynuowane.

11

Porównanie środków odbiałczających stosowanych przy ilościowym oznaczaniu cukrów

58%

Szumska M.

|

1956

|

tom 07

|

nr 2

12

Evaluation of mango byproduct extracts as antioxidant against Pb-acetate-induced oxidative stress and genotoxicity in mice

58%

El Makawy A. I. , Ashoush I. S. , Abd-Elmoneim O. M.

Polish Journal of Food and Nutrition Sciences

|

2015

|

tom 65

|

nr 1

EN

The antioxidant and antiproliferative properties of mango by-products were investigated. This study was carried out to evaluate the protective role of mango peel or kernel defatted extracts against Pb-acetate adverse effects on oxidant/antioxidant status, liver dysfunction biomarkers, histopathological changes and genotoxicity in male mice. Total phenolic content and antioxidant activity of both extracts were evaluated. Two doses of both extracts (50 and 100 mg/kg) were used to evaluate their role against the toxicity of Pb-acetate (500 ppm). Mice given mango extracts with Pb-acetate had signifi cantly lower plasma MDA, AST and ALT and higher glutathione than mice given Pb-acetate alone. Mango extracts prevented the histopathological changes in liver induced by Pb-acetate and decreased the cytotoxicity of lead by increasing the ratio of PCE/NCE. Mango extract treatment reduced the DNA damage induced by Pb-acetate in liver as demonstrated by a reduction in micronuclei and decrease in tail length, tail DNA% and Olive tail moment. It can be concluded that mango by-product extracts have potential to protect from oxidative stress and genotoxicity of lead.

13

Potential alleviation of Chlorella vulgaris and Zingiber officinale on lead-induced testicular toxicity: an ultrastructural study

58%

Mustafa H. N.

Folia Biologica

|

2015

|

tom 63

|

nr 4

14

Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat

58%

El-Sokkary G. H. , Kamel E. S. , Reiter R. J.

Cellular and Molecular Biology Letters

|

2003

|

tom 08

|

nr 2

EN

Oxidative stress is a likely molecular mechanism in lead neurotoxicity. Considering the antioxidant properties of melatonin, this study investigated the neuroprotective potential of melatonin in the hippocampus and corpus striatum of rats treated with lead. Three groups of male rats (control, lead acetate-treated [100 mg/kg], and lead acetate plus melatonin [10 mg/kg] for 21 consecutive days) were used. Levels of products of lipid peroxidation (LPO), glutathione (GSH) and superoxide dismutase (SOD) activity were measured in brain homogenates. Histological changes in the pyramidal cells of the hippocampus and the putamen of the corpus striatum were examined. The results documented increased LPO and decreased GSH and SOD activity in the brain homogenates of lead-treated rats. Histological observations revealed severe damage and a reduction in neuronal density in the hippocampus and corpus striatum. When melatonin was given to lead-treated rats, it almost completely attenuated the increase in LPO products and restored GSH levels and SOD activity. Also, the morphological damage was reduced and neuronal density was restored by melatonin. Considering the ease with which melatonin enters the brain, these results, along with previous observations, suggest that melatonin may be useful in combating free radical-induced neuronal injury that is a result of lead toxicity.

15

The effect of lead on dopamine, GABA and histidine spontaneous and KCI-dependent releases from rat brain synaptosomes

51%

Struzynska L. , Rafalowska U.

|

tom 54

|

nr 3

16

Zawartosc 'endogennego' zelaza w tkankach i plynach ustrojowych krolikow po podaniu octanu olowiu

44%

Kucharczak E. , Jopek Z.

Acta Scientiarum Polonorum. Medicina Veterinaria

|

2003

|

tom 02

|

nr 1

11-17

17

Wplyw cynku na redystrybucje olowiu w ustroju szczura narazonego na 500 PPM octanu olowiu

44%

Kulikowska E. , Moniuszko-Jakoniuk J. , Miniuk K. , Kaluzynski A.

Acta Poloniae Toxicologica

|

1994

|

tom 02

|

nr 2

148-152

18

Zmiany w parametrach biochemicznych u szczurow intoksykowanych wybranymi ksenobiotykami

44%

Zasadowski A. , Barski D. , Terlecka A. , Spodniewska A.

Acta Academiae Agriculturae ac Technicae Olstenensis. Veterinaria

|

1993

|

tom 21

195-204

PL

W pracy przedstawiono wyniki badań dotyczące zmian wybranych parametrów biochemicznych (glukozy, grup-SH oraz aktywności AP i Crpl) w surowicy krwi szczurów kontrolnych oraz zatruwanych octanem ołowiawym (w przeliczeniu na ołów) o stężeniu 2500 mg/dm3, podawanym przez 28 dni z wodą do picia i jednorazowo per os foschlorem w dawce 50 mg/kg m.c. Wymienione związki podawano pojedyńczo i łącznie. Stwierdzono, że octan ołowiawy i foschlor w stosowanych dawkach wykazują wpływ na badane parametry biochemiczne, przy czym nasilenie zmian uzależnione było nie tylko od rodzaju użytego ksenobiotyku, ale również od czasu jaki upłynął od zatrucia i sposobu intoksykacji. Zastosowanie octanu ołowiawego przed foschlorem spowodowało w niektórych okresach czasu nasilenie zmian w badanych parametrach biochemicznych — zwłaszcza aktywności fosfatazy alkalicznej i ceruloplazminy — w porównaniu z intoksykacją pojedyńczą tymi związkami.

RU

В работе представлены результаты исследований изменений биохимических пока зателей (глюкозы, групи-SH, а также активности щелочной фосфатазы и церулошш- мина) в сыворотке крови контрольных крыс и крыс, отравляемых уксуснокислым свинцом в концентрации 2500 мг/дм3 (в пересчете на свинец) в течение 28 дней с питьевой водой и одноразово фосхлором пероралыю в дозе 50 мг/кг массы тела. Указанные соединения давали отдельно и совместно. Констатировали, что уксуснокислый свинец и фосхлор в применяемых дозах влияют на исследованные биохимические параметры, причем интенсивность наблюдаемых изменений зависит не только от вида ксенобиотика, но также от времени, истекшего с момента отравления, и от способа интоксикации. Применение перед фосхлором уксуснокислого свинца усилило в некоторых промежутках времени изменения исследованных биохимических параметров — особенно активности щелочной фосфатазы и церулоплазмина — в сравнении с интоксикацией этими соединениями, применяемыми отдельно.

EN

Results of studies concerned changes of chosen biochemical parameters (glucose, groups-SH, alkaline phosphatase and ceruloplasmine) in blood serum of control and lead acetate intoxicated raits in this paper are presented. Rats were given lead acetate with drinking water in concentration 2500 mg/dm3 (as calculated for lead) during 28 days and once foschlore per os in dose of 50 mg/kg b.w. Above compounds were given seperately and together. It was found that lead acetate and foschlore in applied doses shured effect on the studied biochemical parameters but intensity of changes were dependent not only on the type of used xenobiotic but olso on period of time from poisoning and way of intoxication. Application of lead acetate before foschlore caused in some periods of time intensification of the studied parameters changes particulary alkaline phosphatase and ceruloplasmine when compared to the single intoxications of these compounds.