High resolution and artifact free SPECT reconstruction of the distribution of radioactive sources over the entire imaging field requires exact alignment between the electronic and the mechanical axis of rotations. In this paper, the effect of misalignment between the electronic and the mechanical axis of rotations of SPECT system equipped with low-energy high-resolution and low-energy general-purpose collimators through the field of view has been studied. In addition, the useful dimensions of the SPECT field of view without artifact due to axis of rotation error have been calculated. Furthermore, the roles of digital filters in reducing this effect have been studied.
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