Wyniki wyszukiwania - Biblioteka Nauki

1

Native nucleic acid electrophoresis as an efficient alternative for genotyping method of influenza virus

100%

Pajak B. , Lepek K.

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nr 3

479-483

EN

Influenza viruses are the worldwide major causative agents of human and animal acute respiratory infections. Some of the influenza subtypes have caused epidemics and pandemics among humans. The varieties of methods are available for the rapid isolation and identification of influenza viruses in clinical and environmental samples. Since nucleic acids amplification techniques such as RT-PCR have been adapted, fast and sensitive influenza type and subtype determination is possible. However, in some ambiguous cases other, more detailed assay might be desired. The genetic material of influenza virus is highly unstable and constantly mutates. It is known that single nucleotide polymorphisms (SNPs) results in resistance to commercially available anti-viral drugs. The genetic drift of the virus could also result in weakening of immune response to infection. Finally, in a substantial number of patients co-infection with various virus strains or types has been confirmed. Although the detection of co-infection or presence of minor genetic variants within flu-infected patients is not a routine procedure, a rapid and wide spectrum diagnostics of influenza virus infections could reveal an accurate picture of the disease and more importantly, is crucial for choosing the appropriate therapeutics and virus monitoring. Herein we present the evidences that native gel electrophoresis and MSSCP - a method based on multitemperature single strand conformation polymorphism could furnish a useful technique for minor variants, which escape discovery by conventional diagnostic assays.

2

ReCOMmendations for the treatment of INFLUENZA in children for Primary care physiciAnS – COMPAS INFLUENZA

100%

Doniec Z. , Mastalerz-Migas A. , Jackowska T. , Kuchar E. , Sybilski A.

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nr 2

189-198

EN

Influenza is an acute infectious disease of the airways that occurs in every age group. The course of the disease may have a different severity and clinical picture, from asymptomatic to severe with symptoms of respiratory failure. The possibilities of pandemic infections and serious complications throughout the course of influenza distinguish it from other viral respiratory diseases, prompting us to treat it in a special way. Diagnosis of the disease is usually clinical in nature, and additional studies may be helpful in clinically relevant cases. The drug recommended for treatment and chemoprophylaxis is oseltamivir. Clinical benefits are greatest if treatment starts as early as possible, within 48 hours of the first symptoms of influenza. Clinical studies indicate that early treatment with oseltamivir may shorten the duration of the disease and reduce the risk of its complications. Annual influenza vaccination is the most effective method of preventing this disease, and the only contraindication to vaccination is the occurrence of an anaphylactic or other severe allergic reaction after a previous vaccination

3

Factors affecting decision concerning influenza vaccination among students of medical faculties

100%

Woźniak-Kosek A. , Kempińska-Mirosławska B. , Mendrycka M. , Saracen A. , Hoser G.

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nr 4

829-832

EN

Influenza is one of the most common cyclic respiratory diseases in humans. Methods of prevention are multidirectional, but the most effective and most efficacious way to prevent influenza and its complications is through preventive vaccination. This work aims to determine different factors affecting the decision concerning influenza vaccine. The percentage of people vaccinated against the flu was evaluated, as well as their knowledge of post-influenza complications, etc. among full-time students and bridging studies of nursing and physiotherapy (full-time and part-time) at the University of Technology and Life Sciences in Radom, and students of medicine and pharmacy at the Medical University of Łódź. The research tool was the authors' questionnaire with 18 questions. The surveys conducted, consisting of multiple choice questions, were anonymous. In total, the survey involved 470 students. Overall, the number of people who were vaccinated against influenza in the 2012/13 epidemic season numbered 15 respondents, representing 5.84% of the total group of respondents. For the group of nursing students it was 6%, for physiotherapy students 5%, for students of medicine and pharmacy 14%. The percentage of respondents who said they would get vaccinated if the vaccinaton was free of charge was also low. Increasing the percentage of people vaccinated against influenza (immunization coverage) is a very important measure in preventing influenza epidemics. Therefore, it is necessary to identify the reasons why people are reluctant to be vaccinated against influenza, particularly among students who will work in the future in the health care services sector.

4

Influenza vaccine efficacy in patients aged 60–75 years in the 2016/2017 season

88%

Sławin A. , Brydak L. , Doniec Z. , Mastalerz-Migas A.

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2018

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nr 3

263-266

5

Vaccination against influenza in pregnant women

88%

Brydak L. B. , Nitsch-Osuch A.

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tom 61

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nr 3

6

Development of intracranial sinusogenic complications in the period of increased incidence of influenza infections – analysis of 6 patients hospitalized in the Department of Otolaryngology, Head and Neck Surgery of Poznan University of Medical Sciences in the year 2013

88%

Szyfter W. , Bartochowska A. , Borucki Ł. , Kruk-Zagajewska A.

Polski Przegląd Otorynolaryngologiczny

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2015

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tom 4(3)

20-28

EN

In the period from January 2000 to the end of December 2013 in the Department of Otolaryngology, Head and Neck Surgery of Poznan University of Medical Sciences 21 patients with sinusogenic intracranial complications were treated. It should be emphasized that 6 patients in this group were hospitalized in 2013. In the previous analyzed years there were from 1 to 2 patients per year. This prompted the authors to a detailed presentation of all patients treated in 2013.

7

“Surm on ainus, mis hirmutab”: viirusnakkushaiguste ja nendega seotud vaktsineerimise tähenduse loomine gripi ja koroonaviiruse näitel

88%

Lubi K. , Metsoja E. , Eha K. , Mets-Oja S. , Ruuben L.

Mäetagused

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2021

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tom 79

113-136

EN

Although relatively easy to overcome for young and healthy individuals, seasonal influenza is a disease with considerable health, social, and economic consequences for society, especially for higher-risk groups. Even though vaccination against influenza is the most effective tool to prevent it, vaccination rates remain rather low. Together with the promotion of neoliberal individual responsibility over one’s health, vaccine hesitancy – a complex phenomenon indicating the lower uptake of vaccines compared to the accessibility of information and services – has risen among societies. In previous research, several barriers – for example, psychological, physical, contextual, and sociodemographic – have been identified as preventing influenza vaccine uptake among risk groups. We approach the topic by using the social constructionist theory regarding the meaning construction of illnesses on cultural, individual, and third-party level. The findings outline the importance of meaning construction on all these levels. It appears that culturally influenza has been seen as an inevitable infectious disease related to the northern climate. Due to that, influenza is not considered as a life-threatening disease that would need preventive actions, except some basic hygiene or usage of folk medicine tools (e.g., ginger and garlic). On an individual level, the meaning construction is based on individual experiences, both with the illness and the vaccine – in the case of negative experiences with vaccine, the perception of something useless or even harmful develops. In addition, it appears that people create their own strategies to rationalize rejection of vaccination for themselves. These involve considerations about belonging to the risk group or the possibility to manage daily activities in non-risky manner even when belonging to the risk group. On the third-party level, participants saw the potential of pharmacies to alleviate practical constraints (e.g., tight schedule, daily occupation, etc.). Different media channels are also important in mediating vaccination-related information, but the rationalization and selection of the channels vary widely. The context of the coronavirus changed the vaccination-related perception temporarily for a short term, indicating that fear-based special occasions do not entail a long-term shift in health behaviour as the development of health-related decisions and behaviour is also long-term.

8

Influenza and influenza-like illnesses in Poland in the epidemic season 2010/2011 according to the SENTINEL influenza surveillance system

75%

Romanowska M. , Stefanska I. , Brydak L. B.

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nr 1

EN

The aim of this study was to analyze data collected by the SENTINEL influenza surveillance system in Poland in the first post-pandemic season 2010/2011. The results include weeks 35/2010–17/2011. Physicians registered weekly number of influenza-like illnesses and collected specimens. Laboratory tests were done using PCR and/or real-time PCR or immunofluorescence. Laboratories also isolated the influenza virus. Influenza-like illness incidence amounted to 2802.7/100000. Weekly incidence ranged from 11.3/100000 to 232/100000. The most affected group was children 0–4 years. Influenza-like illness peak occurred between weeks 02/2011 and 11/2011. Influenza infections were confirmed in 34.9% of specimens. More cases were caused by influenza A, including A(H1N1)pdm09 than influenza B (59.9% vs. 40.1%). The isolated strains were similar to A/California/7/2009 or B/Brisbane/60/2008. Season 2010/2011 in Poland did not differ from the rest of Europe. Further improvement is necessary, especially in the area of specimen collection at the beginning of an epidemic season and carrying out the isolation of the influenza virus.

9

Szczepienia przeciwko grypie u personelu medycznego

75%

Nitsch-Osuch A. , Brydak L. B.

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tom 64

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nr 1

119-129

EN

Influenza is one of the most common respiratory diseases affecting people of all age groups all over the world. Seasonal influenza leads to substantial morbidity and mortality on a global scale. Vaccines are undeniably one of the most important health advances of the past century, however, managing influenza in working populations remains a difficult issue. Vaccination of health care workers (HCW) is an efficient way to reduce the risk of occupational infection and to prevent nosocomial transmission to vulnerable patients. Despite this, achieving high immunization rates among those professionals is a challenge. Knowledge and attitudes of healthcare providers have significant impact on the frequency with which vaccines are offered and accepted, but many HCWs are poorly equipped to make informed recommendations about vaccine merits and risks. Principal reasons for vaccination are the willing not to be infected and avoiding transmission to patients and the family. The main reasons for refusing is lack of time, a feeling of invulnerability to vaccination, conviction of not being at risk, of being too young or in good health. Misconceptions about influenza vaccine efficacy, like adverse effects, and fear of contracting illness from the vaccine are significantly associated with noncompliance with vaccination. Therefore, strategies to increase awareness of the importance of recommending influenza immunization among health professionals are required. Med Pr 2013;64(1):119–129

PL

Grypa jest jedną z częstszych infekcji dróg oddechowych, zachorowania na nią występują we wszystkich grupach wiekowych pacjentów na całym świecie. Liczba zachorowań na grypę sezonową i zgonów z powodu jej powikłań jest znaczna w skali globalnej. Szczepienia, również przeciwko grypie, są istotnym osiągnięciem medycyny ostatniego stulecia, jednak problemem pozostaje zwalczanie grypy za pomocą szczepień ochronnych wśród personelu medycznego. Szczepienie personelu medycznego jest procedurą o udowodnionym bezpieczeństwie i skuteczności, zapewnia zapobieganie zachorowaniom wśród pacjentów. Mimo licznych rekomendacji eksperckich stan zaszczepienia pracowników medycznych pozostaje niski. W celu zwiększenia liczby zaszczepionych pracowników medycznych konieczne jest prowadzenie kampanii edukacyjnych, które mają na celu polepszenie stanu wiedzy personelu na temat grypy, jej powikłań, szczepień przeciwko grypie, ze szczególnym uwzględnieniem ich bezpieczeństwa i skuteczności. Szczepieni pracownicy najczęściej decyzję o wykonaniu szczepienia motywują chęcią ochrony siebie oraz chęcią ochrony przed zakażeniem swoich pacjentów i ich rodzin. Z kolei wśród przyczyn nieszczepienia wymieniane są: brak czasu, błędne przekonania o nieskuteczności szczepienia, brak potrzeby szczepienia z powodu bagatelizowania choroby i jej powikłań, obawa przez niepożądanymi odczynami poszczepiennymi. Konieczne jest wdrożenie strategii mających na celu edukację personelu medycznego w zakresie stosowania szczepień przeciwko grypie w celu zwiększenia wyszczepialności przeciwko grypie w populacji pracowników medycznych. Med. Pr. 2013;64(1):119–129

10

Why Don't Blanchard-Kahn ever "Catch" Flu? And how it Matters for Measuring Indirect Cost of Epidemics in DSGE Framework

75%

Torój A.

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nr 3

11

Hemagglutinin stalk domain from H5N1 strain as a potentially universal antigen

75%

Uranowska K. , Tyborowska J. , Jurek A. , Szewczyk B. , Gromadzka B.

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tom 61

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nr 3

12

Detection of the influenza virus yesterday and now

75%

Woźniak-Kosek A. , Kempińska-Mirosławska B. , Hoser G.

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nr 3

465-470

EN

Demographic changes and the development of transportation contribute to the rapid spread of influenza. Before an idea of a 'person to person' spread appeared, divergent theories were developed to explain influenza epidemics in the past. Intensified virological and serological tests became possible after isolation of the human influenza virus in 1933. The first influenza virus detection methods were based on its isolation in egg embryos or cell lines and on demonstration of the presence of the viral antigens. Molecular biology techniques associated with amplification of RNA improved the quality of tests as well as sensitivity of influenza virus detection in clinical samples. It became possible to detect mixed infections caused by influenza types A and B and to identify the strain of the virus. Development of reliable diagnostic methods enabled fast diagnosis of influenza which is important for choosing an appropriate medical treatment.

13

Seasonal influenza vaccination of healthcare workers: a narrative review

75%

Jędrzejek M. J. , Mastalerz-Migas A.

International Journal of Occupational Medicine and Environmental Health

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2021

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tom 35

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nr 2

127-139

EN

Influenza is an acute respiratory disease caused by the influenza virus which often occurs in outbreaks and epidemics worldwide. The World Health Organization recommends annual vaccination of healthcare workers (HCWs) against influenza, because most of them are involved in the direct care of patients with a high risk of influenza-related complications. Given the significance of the disease burden, a targeted literature review was conducted to assess issues related to influenza vaccination among HCWs. The primary aim of this review was to assess the incidence of influenza among medical personnel and healthcare-associated influenza, and to outline the benefits of influenza vaccination for patients and HCWs themselves. Vaccination of HCWs seems to be an important strategy for reducing the transmission of influenza from healthcare personnel to their patients and, therefore, for reducing patient morbidity and mortality, increasing patient safety, and reducing work absenteeism among HCWs. The benefits of influenza vaccination for their patients and for HCWs themselves are addressed in literature, but the evidence is mixed and often of low-quality.

14

Antibody response to DNA vaccine against H5N1 avian influenza virus in broilers immunized according to three schedules

75%

Stachyra A. , Gora-Sochacka A. , Zagorski-Ostoja W. , Krol E. , Sirko A.

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tom 61

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nr 3

15

Aktualna sytuacja epidemiologiczna grypy w województwie śląskim

75%

Kowalska M.

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nr 75

33-40

EN

Influenza is an infectious disease of the respiratory system subject to constant monitoring in terms of the number of new cases and deaths. It was observed that the number of new cases of influenza decreased in the Silesian voivodeship in the second half of March 2020, and it was decided to verify whether it is related to the emergence of a new threat, which is the COVID pandemic. In the descriptive model of the study, the trend of influenza morbidity and hospitalization was analyzed, and at the same time the dynamics of the increase in new SARS-CoV-2 infections was presented. Chronological systematization of important administrative activities limiting development of the epidemic was also carried out. It cannot be ruled out that the observed decrease in the incidence and hospitalization due to influenza in the province of Silesia is related to the restrictive regulations on the organization of work and social life taken to minimize the COVID epidemic. Unambiguous conclusions will require in-depth research and a longer observation period.

PL

Grypa jest chorobą zakaźną układu oddechowego podlegającą stałemu monitorowaniu w zakresie liczby nowych zachorowań oraz zgonów. W drugiej połowie marca 2020 r. zaobserwowano spadek liczby zachorowań na grypę w woj. śląskim i postanowiono sprawdzić, czy ma to związek z pojawieniem się nowego zagrożenia, jakim jest pandemia COVID. W modelu badania opisowego dokonano analizy trendu zachorowalności i hospitalizacji z powodu grypy, a jednocześnie przedstawiono dynamikę wzrostu nowych zakażeń wirusem SARS-CoV-2. Dokonano również chronologicznego usystematyzowania ważnych działań administracyjnych ograniczających rozwój epidemii. Nie można wy-kluczyć, że obserwowany spadek zachorowań i hospitalizacji z powodu grypy w woj. śląskim ma związek z restrykcyjnymi przepisami organizacji pracy i życia społecznego podjętymi dla ograniczenia epidemii COVID. Jednoznaczne wnioskowanie będzie wymagało wnikliwych badań i dłuższego okresu obserwacji.

16

Wybrane zioła w prewencji i wspomaganiu leczenia wirusowych infekcji dróg oddechowych

75%

Siudem P.

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nr 07-08

13-20

EN

Every year, during the cold and flu season, an increase in the incidence of viral respiratory infections and other viral diseases is observed. Vaccination is the primary method of preventing viral diseases. However, it is not always possible to be vaccinated, or the immunity expires after some time. Numerous plant materials can support both prevention and treatment. This article provides an overview of a few selected plant materials, mainly focusing on their impact on influenza and COVID-19 infection.

PL

Każdego roku w sezonie przeziębień i grypy obserwuje się wzrost zachorowań na wirusowe infekcje dróg oddechowych oraz inne choroby wirusowe. Podstawowym sposobem zapobiegania chorobom wirusowym są szczepienia. Nie zawsze jednak możliwe jest przyjęcie szczepienia bądź odporność po pewnym czasie wygasa. Wsparciem zarówno w zapobieganiu, jak i leczeniu mogą być liczne surowce roślinne. W tym artykule przedstawiono przegląd kilku wybranych surowców roślinnych, głównie skupiając się na ich wpływie na grypę i infekcję koronawirusem COVID-19.

17

Factors affecting decision concerning influenza vaccination among students of medical faculties

75%

Wozniak-Kosek A. , Kempinska-Miroslawska B. , Mendrycka M. , Saracen A. , Hoser G.

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nr 4

18

Opinions and behavior of family doctors concerning vaccinating against influenza

75%

Gutknecht P. , Winiarski T. , Trzeciak B. , Molisz A. , Pietrzykowska M. , Nowicka-Sauer K. , Siebert J.

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nr 3

241-243

19

HI antibody kinetics in children with renal failure immunized with inactivated trivalent influenza vaccine

75%

Brydak L. B. , Roszkowska-Blaim M. , Leszczynska B. , Rudnicka H.

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tom 42

|

nr 1

20

Avian influenza in Poland

63%

Smietanka K. , Minta Z.

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tom 61

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nr 3