Wyniki wyszukiwania - Biblioteka Nauki

1

Whipple’s disease as a systemic infectious disease – a case presentation

100%

Maciorkowska M. , Ustymowicz W. , Zakrzewski M. , Pryczynicz A. , Markowski A. , Romatowski J. , Guzińska-Ustymowicz K.

Progress in Health Sciences

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2018

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tom 8(1)

212-218

EN

Introduction: Whipple’s disease is a chronic systemic infectious disorder with Tropheryma whipplei as an etiologic agent, occurring rarely and affecting numerous organs and systems. The variety of symptoms and a non-typical course make it difficult to establish a proper diagnosis. Purpose: In this study, etiopathogenesis, diagnostics and treatment of Whipple’s disease were presented based on the case report of 60-year-old man diagnosed with Whipple’s disease. Case presentation: Persistent diarrhoea with weight loss, lymphadenopathy in the abdominal cavity and moderate microcytic anemia predominated in the clinical picture. Diagnosis was put based on the clinical picture and macroscopic assessment of the small intestine and the presence of macrophages filled with a PAS-positive substance in the lamina propria. To deepen diagnostics, samples collected were assessed showing macrophages with the damaged mucosa, containing numerous elongated micro-organisms whose ultrastructure corresponded to Tropheryma whipplei. The patient’s clinical conditions improved after antibiotic therapy. Conclusions: It is vital to remember about Whipple’s disease in patients with chronic diseases due to a non-specific clinical picture and difficulties in establishing a proper diagnosis. When the disease is diagnosed unequivocally, proper and effective antibiotic therapy should be instituted immediately.

2

Methodologies for measuring mobility in Covid-19 research

100%

Zsigo Z.

Economic and Regional Studies

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2023

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tom 16

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nr 2

3

Support Vector Machine for Susceptibility Modeling of Dengue Fever in Kendari, Southeast Sulawesi

88%

Widayani P. , Sahity A. F. , Saputri A. A.

Geomatics and Environmental Engineering

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2024

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tom Vol. 18, no. 1

29--50

EN

Dengue fever (DF) is an infectious disease that is still a problem in Indonesia. The total death rate due to DF was 705 people in 2021; in 2022, this increased to 1183 (Indonesian Ministry of Health, 2023). Seeing this fact, prevention efforts are still needed when handling DF cases in all of the regions of Indonesia. This research was conducted in the Kendari area of Southeast Sulawesi, where there are still cases of DF. The purpose of this study was to create a spatial model of dengue susceptibility using a support vector machine. Landsat 8 imagery was used to intercept data on building density, vegetation density, land use, and land surface temperatures. Rainfall and humidity variables were obtained from the Meteorological, Climatological, and Geophysical Agency (BMKG). Based on the modeling results, the districts of Wua-wua, Kadia, Barunga, Poasi, and Puuwatu are areas with high susceptibility. The results of testing the susceptibility model to dengue hemorrhagic fever (DHF) in Kendari obtained an area under the curve (AUC) of 0.75, meaning that this model was well-accepted.

4

MicroRNA and Immune Response to Viral, Bacterial and Fungal Infections

88%

Agosile O. O. , Benson U. , Oduwe U. , Okei N. C. , Fajobi S. J. , Akachukwu S. O. , Oyetayo B. O. , Faniyi A. J. , Njoku P. C. , Olagunju A. S.

World News of Natural Sciences

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2022

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tom 44

24-42

EN

Several kinds of microRNA have been studied as prospective biomarkers in the pursuit of better diagnostics tests for infectious diseases. miRNA which is processed mostly from introns plays a significant role in gene expression involving cell differentiation, proliferation, apoptosis, metabolism, and immune response. Many miRNA mimics or inhibitors are in their clinical phases and advancement in RNA interference will make miRNA become effective tools in the treatment of human infectious diseases. miRNA has been discovered to be largely involved in viral gene regulation as well as the change of host cellular genes during viral infections. The role of miRNA in most bacterial infections has not been thoroughly explored compared to viral infections. Recent studies have highlighted the vital role of host immunity against bacterial infections. miRNA that is sequenced due to fungal infections bear a close similarity to those produced in response to allergy or inflammation. Host-derived miRNA plays a vital role in immune regulation; inflammatory responses may be enhanced or inhibited by its upregulation or downregulation. Here, we outlined the involvement of microRNA in viral, fungal, and bacterial infections and the immune response associated. Further studies on these, will provide advanced diagnostic and treatment protocols for infectious diseases.

5

Professor Jan Karol Kostrzewski, MD (1915-2005) - centenary anniversary of the birth

88%

Naruszewicz-Lesiuk D.

Roczniki Państwowego Zakładu Higieny

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2016

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tom 67

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nr 3

6

Impact of global warming on the spread of infectious diseases

88%

Wieliczko A. , Staroniewicz Z.

Medycyna Weterynaryjna

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2010

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tom 66

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nr 06

363-365

EN

After years of scientific and public discussion concerning a temperature rise resultant from human activity and the on-going industrialisation, the global warming has become an evident fact. The effect of the temperature rise and the climate change will surely alter epidemiological aspects of some infectious diseases. In this review, we try to analyse various data concerning the impact of global warming on the spread of infectious diseases caused by bacterial, viral and protozoan agents. Certainly, it is extremely important for veterinarians and public health that some diseases have altered in their epidemiological aspects and distribution. Some new diseases may emerge; others, previously endemic, may migrate to new geographical regions. The review is focused on pathogens important to both humans and livestock, such as malaria, dengue, bluetongue, West Nile virus, tick-born diseases and infectious diarrhoeas. There are still few scientific papers on the subject, because of numerous difficulties involved in conducting such studies, such as their long time of duration, multiple factors involved in such predictions, and complicated mathematical models containing climate and epidemiological data.

7

Percentage of B lymphocytes and the presence of CD21 receptor on lymphocytes in patients with infectious mononucleosis

88%

Lis-Tonder J. , Fota-Markowska H. , Modrzewska R. , Tomasiewicz K.

Bulletin of the Veterinary Institute in Puławy. Supplement

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2002

8

Novel approaches for developing vaccines

88%

Babiuk L. A.

Bulletin of the Veterinary Institute in Puławy

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1998

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tom 42

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nr 1

9

Method of Assessing the Potential Risk to the Health of the Population During Recreational Water Withdrawal

75%

Rybalova O. , Malovanyy M. , Bondarenko О. , Proskurnin O. , Belokon K. , Korobkova H.

Journal of Ecological Engineering

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2022

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tom Vol. 23, nr 5

81--91

EN

The use of polluted water bodies for recreation poses a risk of infectious diseases. This fact necessitates taking into account bacteriological indicators to determine the danger of recreational water use. The aim of the article was to develop a new method for assessing the potential risk to population health during recreational water use. A new method for assessing the potential risk to population health during recreational water use has been proposed, which combines the identification of potential risk according to chemical and bacteriological indicators. A new classification of water hazard levels according to the values of risk to population health has been developed. The value of the potential risk to the population health during the recreational use of 6 beaches in the urbanized territories of the city of Kharkiv and its suburbs (Ukraine) was obtained. It was established that bacteriological contamination has the probability of a very large impact on public health (hazard class 5). To compare the methods of assessing the risk to population health during recreational water use, the hazard index (NI) was determined according to the chemical indicators of the quality of water bodies in the city of Kharkiv. The use of the assessment of the potential risk to population health for the environmental regulation of the discharge of pollutants into a water body with wastewater is justified.

10

Rift Valley fever – a growing threat to humans and animals

75%

Kwasnik M. , Rozek W. , Rola J.

Journal of Veterinary Research

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2021

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tom 65

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nr 1

11

Lymphocyte subpopulations in the bitches with pyometra treated with aglepristone

75%

Jurka P. , Faundez R. , Winnicka A.

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2010

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tom 54

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nr 4

EN

The purpose of the study was to compare flow cytometric and haematologic variables in dogs with spontaneous endometritis pyometra complex (EPC) treated with aglepristone to healthy controls. Peripheral blood mononuclear cells: CD3, CD4, CD8, and B lymphocytes (CD21) were analysed by flow cytometry and white blood cell count. Significant differences were observed (P≤0.01) between control (C) and study (S) group in the total number of leukocytes, monocytes and granulocyte populations (without lymphocytes) on beginning, after 7 d, and return to reference value after 14 d of the treatment. The percentage of the T-cell (CD3+) at the beginning was 47.22 ±9.64% of total lymphocytes, in contrast to B lymphocytes (CD21+) that represented the smallest percentage of 14.24 ±7.74% (P≤0.01). The percentage of the lymphocytes CD4+ was 27.42 ±5.53% and CD8+ was 25.18 ±4.36%. The percentage of CD3+ lymphocytes was increasing throughout the experiment in group C and gradually decreased in group S from 14th to 28th d of dioestrus. No differences in the number of CD3+, CD4+, CD8+, and CD21+ lymphocytes between group C and S on the 14th and 28th d of dioestrus (P≥0.05) were observed. The number of CD8+ cells in group S decreased gradually from day 14 to 28 but no statistical differences were noted. Treatment of pyometra with aglepristone decreased the number of leukocytes, monocytes, and granulocytes to referential value but statistically significant influence on the level of subpopulations of T and B lymphocytes was not observed. The results enabled to estimate for the first time the number of lymphocyte subpopulations in dioestrus in both healthy bitches as well as in those suffering from pyometra.

12

Avian tuberculosis in a captive cassowary (Casuarius casuarius)

75%

Krajewska M. , Czujkowska A. , Weiner M. , Lipiec M. , Szulowski K.

Bulletin of the Veterinary Institute in Puławy

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2015

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tom 59

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nr 4

EN

The paper describes avian tuberculosis in a captive bred cassowary. A two-and-a-half-year-old bird was obtained by a Polish zoo in 2010 from the Netherlands under conditions compliant with the recommendations of the European Association of Zoos and Aquaria. Despite being of small size for the age, the bird appeared healthy and showed no signs of the disease until the day when it was found recumbent in its pen. Later on it was euthanised due to lack of treatment possibilities. Pathological changes typical of avian tuberculosis were found in the liver and spleen. Mycobacterium avium ssp. avium was cultured from both organs.

13

An universal tool for the analysis of effectiveness of insecticides

75%

Rabczenko D. , Gliniewicz A. , Kluge B. , Piekarski S.

Pestycydy

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2011

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nr 1-4

EN

Insecticides have leading role in reduction of population of arthropods, especially vectors of infectious diseases. Efficacy of insecticides is usually proved on biological material and described after adjusting the values of parameters in some “theoretical” function to the experimental results. In the standard approach, such function is described by probit regression. However, in some cases reaction of the population on pesticide differs from those which could be described by the probit regression curve and the results could not be properly assessed. The aim of this study was to elaboratie a practical tool for evaluating insecticide/acaricide efficacy, more universal than classical probit calculation. Software performing analysis was created using R 2.13.1 statistical software.

14

75%

Pospisil R.

Electronic Journal of Polish Agricultural Universities. Series Economics

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2015

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tom 18

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nr 4

15

Metody i vozmozhnosti primenenija ehlektronnykh sistem dlja povyshenija immuniteta novorozhdennykh zhivotnykh

75%

Garasymchuk I. , Potapskijj P. , Pancir Y. , Gordijjchuk I.

Motrol. Motoryzacja i Energetyka Rolnictwa

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2015

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tom 17

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nr 5

16

Choroba zakaźna ludzi jako determinanta działania Policji w ramach operacji policyjnej

75%

Socha G.

Wiedza Obronna

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2021

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tom nr 3

67--78

PL

Opierając się na doświadczeniach z Covid-19, wystąpienie choroby zakaźnej zarówno wywołuje zagrożenie dla życia czy zdrowia ludzkiego, ale także może wywołać zagrożenie dla bezpieczeństwa i porządku publicznego, np. w przypadku „sprzeciwu społecznego” przeciwko wprowadzanym obostrzeniom, co jednocześnie może powodować konieczność angażowania do działania pododdziałów zwartych Policji oraz policjantów innych rodzajów służb, jak np. służby kryminalnej. Mając powyższe na uwadze, jak również zakres zadań nałożonych na Policję w czasie stanu epidemii wprowadzonego w związku z rozprzestrzenianiem się choroby zakaźnej Covid-19, za zasadne należałoby uznać realizację policyjnych działań na rzecz zapobiegania i zwalczania choroby zakaźnej w ramach operacji policyjnej o zasięgu krajowym. Zarządzenie operacji z pewnością wpłynęłoby na sprawność w zakresie koordynacji policyjnych działań, zarówno w wymiarze krajowym, jak i międzyinstytucjonalnym.

EN

Based on the experience with Covid-19, the occurrence of an infectious disease both poses a threat to human life or health, but also may pose a threat to public safety and order, e.g. in the case of "social opposition" against the introduced restrictions, which at the same time may require the involvement of for the operation of compact units of the Police and policemen of other types of services, such as the criminal service. Bearing in mind the above, as well as the scope of tasks imposed on the Police during the epidemic introduced in connection with the spread of the Covid-19 infectious disease, it would be reasonable to implement police actions to prevent and combat an infectious disease as part of a national police operation. The ordering of the operation would certainly have an impact on the efficiency of police coordination, both at the national and inter-institutional levels.

17

Highly pathogenic avian influenza H5N8 in Poland in 2019–2020

75%

Smietanka K. , Swieton E. , Kozak E. , Wyrostek K. , Tarasiuk K. , Tomczyk G. , Konopka B. , Welz M. , Domanska-Blicharz K. , Niemczuk K.

Journal of Veterinary Research

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2020

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tom 64

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nr 4

18

Analysis of the impact of education level on the sense of coherence and opinion concerning carrying out preventive vaccination

75%

Makara-Studzinska M. , Sidor K. , Kalinowski P.

Journal of Pre-Clinical and Clinical Research

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2015

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tom 09

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nr 1

EN

Introduction. Nowadays, preventive vaccination is still the most effective method of countering and combating infectious diseases. Objective. The objective of the present study was to take into consideration the education of the respondents while learning about their views and attitudes towards both compulsory and recommended preventive vaccination in Poland. Materials and methods. An interview survey was conducted among 370 respondents – students and young parents residing in the Lublin province of eastern Poland. The research tools were an authors’ questionnaire and a Life Orientation Questionnaire (SOS-29). Results. The majority of respondents with secondary education (77.40%), undergraduate education (63.71%), and graduate education (55.07%) stated that sometimes preventive vaccination may have life-threatening consequences. A very small percentage of both groups of respondents with secondary and undergraduate education expressed the opinion that such situations often happen (1.69% vs. 1.61%), but this opinion was not shared by any of the respondents with graduate education. Analyzing the dependency between the sense of coherence and one’s level of education, a significant difference between the respondents with secondary education and undergraduate education was observed. Although differences between respondents with graduate education and respondents with undergraduate education existed, they were not very significant. Conclusions. The educational background of the respondents has an impact on their opinions on preventive vaccination. The great majority of respondents believed that vaccination is necessary in order to avoid many dangerous diseases. Respondents with graduate education evaluated preventive vaccination in a positive or a very positive way. The subjects differed in their global sense of coherence together with its components. The general sense of coherence stood at an average level, with the mean of 129.02 points. The highest results were obtained by the respondents in the area of resourcefulness, which is a belief that they had at their disposal remedial resources, including preventive vaccination.

19

Evaluation of Wondfo Rapid Diagnostic Kit (Pf-HRP2/PAN-pLDH) for diagnosis of malaria by using nano-gold Immunochromatographic assay

75%

Wu J. , Peng Y. , Liu X. , Li W. , Tang S.

Acta Parasitologica

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2014

|

tom 59

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nr 2

EN

Prompt and accurate diagnosis is necessary to start adequate treatment for different affecting species including P. falciparum and P. vivax. Here we described the Wondfo Rapid diagnostic Kit (Pf-HRP2/PAN-pLDH) for the detection of P. falciparum and pan-plasmodium in patient specimen by using a nano-gold immunochromatographic assay. Our rapid assay adapted nano-gold labeling techniques and the monoclonal antibodies (mAbs) against both histidine rich protein-2 (Pf HRP-2) of P. falciparum and pan plasmodium-specific pLDH (pan pLDH). The established two-antibody sandwich immunochromatographic assay could detect P. falciparum and pan-plasmodium. The sensitivity and specificity of Wondfo rapid diagnostic kit were determined by comparing with the “gold standard” of microscopic examination of blood smears. In this study1023 blood samples were collected from outpatient clinics in China and Burma, and detected by both Wondfo kit and microscopic examination. The detection sensitivity and specificity of Wondfo rapid diagnostic kit were 96.46% and 99.67% for P. falciparum (HRP2), 95.03% and 99.24% for pLDH, 96.83% and 99.74% for non-falciparum species, 96.70% and 99.74% for P. vivax, respectively. These results indicate that Wondfo rapid diagnostic assay may be useful for detecting P. falciparum and non-P. falciparum (especially P.v.) in patient specimen.

20

Recognition COVID-19 as an occupational disease in Poland – definition, criteria and recommendation

75%

Wiszniewska M. , Rybacki M. , Lipińska-Ojrzanowska A. , Szkiela M. , Walusiak-Skorupa J.

Medycyna Pracy

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2023

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tom 74

|

nr 5

435-442

EN

A major challenge over the pandemic period was to establish the criteria for recognizing COVID-19 as an occupational disease. The European Center for Disease Prevention and Control has attempted to estimate the incidence of COVID-19 in individual occupational groups and economy sectors in the European Union and the United Kingdom, and to identify possible factors increasing the transmission of the virus at workplaces. Legal regulations of various countries in the world allow COVID-19 to be recognized as an accident at work and/or an occupational disease. In Poland, an occupational disease is defined as a disease caused by harmful factors occurring in the work environment or connected with performing a given job, included in the official list of occupational diseases. When assessing occupational exposure in the healthcare sector, it should be considered that healthcare workers include all persons in contact with patients or their biological material, as well as employees who are not medical professionals but who share a common space with patients due to the nature of their work. The latter group includes administrative and technical employees, control and rescue service workers, people supporting medical staff, and employees of nursing homes. In the case of non-medical occupations, the decision to recognize COVID-19 as an occupational disease should be made on an individual basis, after confirming a significant risk of contracting a SARS-CoV-2 virus infection at the workplace and in the absence of evidence of a non-occupational source of infection. An assessment of occupational exposure should always include evaluating the possibility of SARS-CoV-2 transmission.