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On optimal boundary and distributed control of partial integro-differential equations

100%

Khurshudyan A. Z.

Archives of Control Sciences

2014

tom Vol. 24, no. 1

5-25

A method of optimal control problems investigation for linear partial integro-differential equations of convolution type is proposed, when control process is carried out by boundary functions and right hand side of equation. Using Fourier real generalized integral transform control problem solution is reduced to minimization procedure of chosen optimality criterion under constraints of equality type on desired control function. Optimality of control impacts is obtained for two criteria, evaluating their linear momentum and total energy. Necessary and sufficient conditions of control problem solvability are obtained for both criteria. Numerical calculations are done and control functions are plotted for both cases of control process realization.

Improving the insulin therapy for diabetic patients using optimal impulsive disturbance rejection: Continuous time approach

72%

Dodek M. , Miklovičová E. , Halás M.

Biocybernetics and Biomedical Engineering

2024

tom Vol. 44, no. 2

414--430

The paper proposes a new model-based optimization approach to improve the clinical efficiency of compensatory insulin bolus treatment in diabetic patients, aiming to mitigate the consequences of diabetes. The most important contribution of this paper is a novel methodology for determining the optimal parameters of insulin treatment, namely the size and timing of insulin boluses, to effectively compensate for carbohydrate intake. This concept can be seen as the so-called optimal model-based bolus calculator. The presented theoretical framework deals with the problem of optimal disturbance rejection in impulsive systems by minimizing an integral quadratic cost function. The methodology considers a personalized empirical transfer function model with static gains and time constants as the only parameters assumed to be known, making the bolus calculator more straightforward to implement in clinical practice. Contrary to other techniques, the proposed methodology considers impulsive insulin administration in the form of boluses, which is more feasible than continuous infusion. In contrast to the conventional bolus calculator, the proposed algorithm allows for maximizing therapy performance by optimizing the relative time of insulin bolus administration with respect to carbohydrate intake. Another feature to highlight is that the solution of the optimization problem can be obtained analytically, hence no numerical iterative solvers are required. Additionally, the continuous-time domain approach allows for a much finer adjustments of the insulin administration timing compared to discrete-time models. The proposed approach was validated in an in-silico study, which demonstrated the importance of systematically determined insulin-carbohydrate ratio and the relative delay between disturbance and its compensation. The results showed that the proposed optimal bolus calculator outperforms the traditional suboptimal formula.

Almost periodic synchronization of fuzzy cellular neural networks with time-varying delays via state-feedback and impulsive control

72%

Li Y. , Wang H. , Meng X.

International Journal of Applied Mathematics and Computer Science

2019

tom Vol. 29, no. 2

337--349

In this paper, we are concerned with drive-response synchronization for a class of fuzzy cellular neural networks with time varying delays. Based on the exponential dichotomy of linear differential equations, the Banach fixed point theorem and the differential inequality technique, we obtain the existence of almost periodic solutions of this class of networks. Then, we design a state feedback and an impulsive controller, and construct a suitable Lyapunov function to study the problem of global exponential almost periodic synchronization for the drive-response systems considered. At the end of the paper, we provide an example to verify the effectiveness of the theoretical results.

Rapid exponential stabilization of nonlinear continuous systems via event-triggered impulsive control

72%

Dlala M.

Demonstratio Mathematica

2022

tom Vol. 55, nr 1

470--481

This article investigates the problem of rapid exponential stabilization for nonlinear continuous systems via event-triggered impulsive control (ETIC). First, we propose a trigger mechanism that, when triggered by a predefined event, causes the closed-loop system exponentially stable. Then, the exponential stabilization is achieved by the designed ETIC with or without data dropout. The case where there are delays in the ETIC signals is also studied, and the exponential stabilization is proved. Finally, a numerical study is presented, along with numerical illustrations of the stability results.