Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl
Ograniczanie wyników
Czasopisma help
Lata help
Autorzy help
Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 60

Liczba wyników na stronie
first rewind previous Strona / 3 next fast forward last
Wyniki wyszukiwania
Wyszukiwano:
w słowach kluczowych:  immunology
help Sortuj według:

help Ogranicz wyniki do:
first rewind previous Strona / 3 next fast forward last
EN
The aim of the present study was to investigate the effect of Finnish sauna bathing on a white blood cell profile, cortisol levels and selected physiological indices in athletes and non-athletes. The study evaluated 9 trained middle-distance runners and 9 male non-athletes. The subjects from both groups participated in 15-minute sauna sessions until their core temperature rose by 1.2°C (mean temperature in the sauna room was 96° ± 2°C; relative humidity was 15 ± 3%) with a 2 minute cool down with water at a temperature of 19-20°C. Body mass was measured before and after the session and blood samples were taken for tests. Rectal temperature was monitored at five-minute intervals during the whole session. Serum total protein, haematological indices and cortisol levels were determined. Sauna bathing caused higher body mass loss and plasma volume in the athletes compared to the group of non-athletes. After the sauna session, an increased number of white blood cells, lymphocyte, neutrophil and basophil counts was reported in the white blood cell profile. Higher increments in leukocyte and monocyte after the sauna bathing session were recorded in the group of athletes compared to untrained subjects. The obtained results indicated that sauna bathing stimulated the immune system to a higher degree in the group of athletes compared to the untrained subjects.
EN
Two yeast casein kinase type-I sp«cies of 45 kDa and 27 kDa (CK1) were purified to apparent homogeneity and used for investigation of their immunological affinity. Antiscra against the two kinases were isolated; the antibody agaiast the 45 kDa kinase did not react with the 27 kDa enzyme. The 27 kDa casein kinase was recognized only by its own antibody. The obtained data strongly suggest that the low molecular mass CK-1 is not a proteolytic product of the 45 kDa kinase species.
PL
Częstotliwość występowania alergii pokarmowych w ostatnich latach wzrasta. Zjawisko to zbiega się ze zmianami zachodzącymi w zwyczajach żywieniowych i środowisku. Większość alergii pokarmowych to immunologiczne reakcje na żywność przebiegające z udziałem przeciwciał IgE. Artykuł przedstawia przykłady alergenów pokarmowych (pochodzenia roślinnego i zwierzęcego).
EN
The incidence of food allergy has been increasing, especially during the last few years. This phenomenon coincides with the changes in the eating habits and in the environment. The most of food allergies are IgE-mediated immunological reactions to specific foods. The paper presents the review of food allergies (of plant or animal origin).
EN
This paper presents an algorithm for nonlinear adaptive control of the viral load in HIV-1 infection. The infection model considered is a reduced complexity nonlinear state-space model with two state variables, that represent the plasma concentration of uninfected and infected CD4+ T-cells of the human immune system. The viral load is assumed to be proportional to the concentration of infected cells. First, a change of variables that exactly linearizes the system is obtained. For the resulting linear system the manipulated variable is obtained by state feedback. To compensate for the uncertainty in the infection parameter of the model an estimator based on a Control Lyapunov Function is designed.
EN
Reaction of primary C55-allylic alcohol moraprenol (WT3C7-9-OH, a polyprenol from mulberry leaves) with triethylamine in the presence of phosphorus oxychloride leads to a quaternary ammonium chloride with a good yield (72%) and high cis-stereoselectivity of the terminal isoprene unit. Cationic polyprenyl derivatives may be useful for transfection and immunological studies
10
75%
EN
Observation of nature is often the inspiration for unconventional and innovative ideas, proposals, suggestions, overall concepts for carrying out modeling phenomena and technical processes, economic, processing and analysis of statistical data. Artificial neural networks, genetic algorithms and evolutionary algorithms were created as an imitation of biological solutions. In recent years, the rapid development of immunological algorithms which are based on the action of the human immune system, has occurred. These algorithms are used in mathematics, engineering, problem solving in decision making, management, economics, finance. At the beginning of this article we describe the action of the human immune system, which is the basis for the construction of immune algorithms. Then we present the most important mechanisms influencing the operation and construction of the algorithms based on biological mechanisms of the immune system, in particular the negative selection, immune network, clonal selection. Then we describe how the elements and mechanisms of artificial immune system algorithms are represented to enable modeling, processing and analysis of data. In the last part of the article to illustrate the wide range of possibilities of using immune algorithms to solve various sorts of problems from a completely different fields, we present examples of applications that involve the assessment of bank borrowers, the task of coloring a graph belonging to combinatorial optimization problems, a multi-dimensional classification, fault detection.
PL
W artykule przedstawiono wstępne wyniki badań detekcji anomalii w przebiegach czasowych bazującej na sztucznych systemach immunologicznych, a w szczególności selekcji negatywnej. Przeprowadzono badania mające na celu wybór najkorzystniejszej struktury systemu detekcyjnego jak również dokonano wyboru najkorzystniejszej liczby przedziałów i jednakowych bitów.
EN
Preliminary analysis of anomaly detection algorithm basing on artificial immune system is presented in the paper. The detection of anomaly applies negative selection which human body uses for virus recognition. Aim of the research was to choose the best structures and numbers of identically bits and numbers of intervals of the tested algorithm.
EN
ObjectivesAs a chronic, recurrent, immunologically mediated systemic disease and a common cause of dermatological problems, psoriasis is often a subject of scientific research. Skin changes located on the hands can cause difficulties and limitations in the performance of professional activities, especially manual ones. The main role in pathogenesis is played by immunological factors – improper functioning of the components of the immune system, among others, T lymphocytes and cytokines like interleukin-12 (IL-12), interleukin-22 (IL-22) and interferon gamma (IFN-γ).Material and MethodsThe obtained tissue and blood were destined for RNA isolation. The RNA was then subjected to a reverse transcription reaction. The relative gene expression level was evaluated by the real-time polymerase chain reaction for IL-12B, IL-22 and IFN-γ genes, and presented as the relative quantification (RQ) value, relative to the reference gene GAPDH. In addition, a correlation analysis of the expression level of selected genes with the clinical course of the disease, as assessed by the Psoriasis Area and Severity Index (PASI), the Body Surface Area (BSA) and the Dermatology Life Quality Index (DLQI) scores was performed.ResultsStatistical analysis confirmed a significant increase in RQ values for IL-12B, IL-22 and IFN-γ in the group of psoriatic patients vs. the control group. A positive correlation was also found between BSA and PASI and RQ for the IL-12B gene.ConclusionsIncreased expression levels of IL-12B, IL-22 and IFN-γ genes in psoriatic skin confirm that selected cytokines play an important role in the initiation and sustenance of psoriasis.
|
|
nr 2
XX
The influence of iodine-iodide solution on (he biochemical and immunological properties of human thyroglobulin (hTg) were studied. Human Tg preincubated with the iodine-iodide solution is split to small molecular mass fragments after disulphide bridge reduction with dithiothreitol. The peptide bond cleavage by iodine pretreatment and reduction is possibly linked with the coupling reaction of diiodotyrosyl residues. Pretreatment of hTg with iodine-iodide solution at 1 -10 |iM decreased the binding of autoantibodies to hTg. The iodine-iodide induced inactivation of hTg autoepitopes is pH dependent and is possibly caused by iodination of tyrosyl residues present in the epitope structure.
first rewind previous Strona / 3 next fast forward last
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.