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Expression and crossing over of genes of immunoglobulin heavy chains in pigs with translocation RCP [7;13][q13;q46]

100%

Wegrzyn J. , Skiba E. , Danielak-Czech B.

Roczniki Naukowe Zootechniki

1999

tom 26

nr 4

Novel prognostic molecular factors: a quantum leap in the field of chronic lymphocytic leukemia

84%

Zakrzewska E. , Pirog M. , Purkot J. , Giannopoulos K.

Folia Histochemica et Cytobiologica

2017

tom 55

nr 3

Expression of IgG immunoglobulin heavy chain IGHGA1 and IGHGA2 genes and absorption and catabolism of these proteins in lambs

84%

Krzyscin P. , Skiba E. , Wegrzyn J.

Annals of Animal Science

2002

tom 02

nr 1

Effect of nuclear matrix attachment regions on transgene expression in tobacco plants

84%

Nowak W. , Gawlowska M. , Jarmolowski A. , Augustyniak J.

Acta Biochimica Polonica

2001

tom 48

nr 3

Matrix attachment regions (MARs) are thought to participate in the organization and segregation of independent chromosomal loop domains. Although there are several reports on the action of natural MARs in the context of heterologous genes in transgenic plants, in our study we tested a synthetic MAR (sMAR) with the special property of unpairing when under superhelical strain, for its effect on reporter gene expression in tobacco plants. The synthetic MAR was a multimer of a short sequence from the MAR 3 end of the immunoglobulin heavy chain (IgH) enhancer. This sMAR sequence was used to flank the β-glucuronidase (GUS) reporter gene within the T-DNA of the binary vector pBI121. Vectors with or without the sMARs were then used to transform tobacco plants by Agrobacterium tumefaciens. Transgenic plants containing the sMAR sequences flanking the GUS gene exhibited higher levels of transgene expression compared with transgenic plants which lacked the sMARs. This effect was observed independently of the position of the sMAR at the 5 side of the reporter gene. However, variation of the detected transgene expression was significant in all transformed plant populations, irrespective of the construct used.

Serum tumor necrosis factor-alpha and interleukin-10 levels as markers to predict outcome of patients with chronic lymphocytic leukemia in different risk groups defined by the IGHV mutation status

67%

Lech-Maranda E. , Grzybowska-Izydorczyk O. , Wyka K. , Mlynarski W. , Borowiec M. , Antosik K. , Cebula-Obrzut B. , Makuch-Lasica H. , Nowak G. , Klimkiewicz-Wojciechowska G. , Wawrzyniak E. , Bilinski P. , Robak T. , Warzocha K.

Archivum Immunologiae et Therapiae Experimentalis

2012

tom 60

nr 6