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Current experimental strategies for investigating human hematopoietic stem cell biology

100%

Ratajczak M. Z. , Gewirtz A. M.

Folia Histochemica et Cytobiologica

1996

tom 34

nr 2

Immunocytochemical analysis of the tissue location of cytokines [IL-2 and IL-12] in neuroendocrine lung cancer

84%

Kasprzak A. , Przewozna M. , Zabel M. , Pankowski J. , Surdyk-Zasada J.

Folia Morphologica

2003

tom 62

nr 3

301-303

The study aimed at immunocytochemical evaluation of the cellular expression of two cytokines, IL-2 and IL-12 in lung carcinoids (n = 10), following the earlier demonstration of two markers of endocrine tumours (chromogranin A and NSE — neuron-specific enolase). In the immunocytochemical studies the classical avidin-biotinylated peroxidase (ABC) technique was used. Results of the tests were semiquantitatively appraised employing the IRS scale. In 9/10 cases intense reaction (score: 6–12 points) was noted for both lung neuroendocrine markers. In all cases of carcinoma co-expression of IL-2 and IL-12 was demonstrated in cells of the tumours. The cytokines showed a cytoplasmic localisation of mean (score: 3–4 points) or high (score: 6–12 points) intensity of reaction. Our studies point to a possible role of the two cytokines in the proliferation of lung neuroendocrine carcinomas but more detailed analysis is required on a broader material.

Potassium-stimulated GABA release is a chloride-dependent but sodium- and calcium-independent process in cultured astrocytes

67%

Albrecht J. , Bender A. S. , Norenberg M. D.

Acta Neurobiologiae Experimentalis

1998

tom 58

nr 3

Phospho-H2AX foci in interphase and mitotic root meristem cells of Vicia faba following hydroxyurea- and aphidicolin-induced replicational stress and during premature chromosome condensation [PCC]

67%

Rybaczek D. , Bodys A. , Maszewski J.

Biological Letters

2005

tom 42

nr 2 Spec.Vol.