Wyniki wyszukiwania - Biblioteka Nauki

1

Changes in the pancreas caused by different types of hypertension

100%

Nowińska P. , Kasacka I.

Acta Biochimica Polonica

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2017

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tom 64

|

nr 4

591-595

EN

Hypertension is considered a lifestyle disease. Unfavorable forecasts predict a significant increase in the number of patients suffering from this disorder. Many changes in various organs have been observed as a result of ischemia. An interesting question arises of whether differences between the mechanisms occurring in different types of hypertension could produce different effects in the organs. It is well known that there is a close relationship between hypertension and insulin resistance. On the other hand, insulin resistance is the main cause of type 2 diabetes, which develops in parallel with changes in the pancreas. The pancreas is a very important organ since it produces enzymes crucial for the digestive process, as well as performs an important endocrine function. The work presented here focuses primarily on the latter issue. The authors present an overview of contemporary literature concerning the influence of different types of hypertension on the function of the pancreas.

2

White blood cells count and its populations in patients with acute coronary syndromes and co-morbidities

80%

Vakaliuk I. , Alghzawi I.

Critical Care Innovations

|

2021

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tom 4

|

nr 2

1-7

EN

INTRODUCTION: Acute coronary syndromes (ACS) and sudden death cause most ischemic heart disease (IHD)- related deaths, which represent 1.8 million deaths per year, with similar numbers of men and women dying from coronary artery disease (CAD). It’s known that inflammation plays crucial role in atherosclerotic plaque formation and its destabilization. The purpose of this study is to evaluate of white blood cells count in its subpopulation in patients with ACS and modifiable cardiovascular risk factors – arterial hypertension and 2 type Diabetes Mellitus (DM). MATERIAL AND METHODS: In this observational cohort trial we observed of 184 patients with ACS. All patients were randomized into four groups: 1st group - 42 patients with ACS without arterial hypertension (AH) or DM; 2nd group – 56 patients with ACS and previous AH; 3rd group – 42 patients with ACS and 2 type DM; and 4th group – 44 patients with ACS and AH and DM. We studied of leukocytes count and their subpopulations in blood. RESULTS: The mean white blood cells count was significant higher in patients with ASC, compared with control group: 8.23 [6.50; 9.40] vs 5.49 [5.20; 5.70] (p<0.001). Similarly, ACS caused increase of leukocytes subpopulation count in blood. The significant higher count of white blood cells was observed in patients with ACS and co-morbidities: 2 type DM and its association with AH. In patients with ACS and previous AH we observed significant lower neutrophils count (p<0.05), but increased quantity of lymphocytes, compared with patients with ACS without co-morbidities (p<0.001). DM and its association with AH was characterized of neutrophils, lymphocytes and monocytes counts growth. CONCLUSIONS:ACS is characterized of raised white blood cells count and its population, especially in cases of association with 2 type Diabetes Mellitus.

3

Ocena jakości życia pacjentów z nadciśnieniem tętniczym krwi.

80%

Dudzic P. , Uchmanowicz I. , Jankowska-Polańska B. , Chudiak A.

Współczesne Pielęgniarstwo i Ochrona Zdrowia

|

2015

|

nr 1

5-8

PL

Wstęp. Nadciśnienie tętnicze dotyczy 9,5 mln osób między 18. a 79. rokiem życia, co odpowiada 32% populacji ogólnej. Choroba znacznie utrudnia codzienne życie przez ograniczenia związane z nasileniem objawów, procesem leczenia oraz czynnikami zaostrzającymi jej przebieg, wpływając na ocenę jakości życia. Cel pracy. Ocena jakości życia chorych z nadciśnieniem tętniczym krwi oraz zbadanie, jakie czynniki wpływają na jej ocenę. Materiał i metody. Badania przeprowadzono wśród 70 pacjentów (39 kobiet i 31 mężczyzn) 4. Wojskowego Szpitala Klinicznego z Polikliniką we Wrocławiu od stycznia do maja 2014 r. W badaniu wykorzystano analizę dokumentacji medycznej pacjentów oraz kwestionariusz ogólny oceny jakości życia SF-36 (Short Form-36). Wyniki. Z badano k orelacje p oszczególnych g rup z miennych n a w ymiar fizyczny (PCS), mentalny (MCS) oraz ogólny indeks QoL: płeć (PCS – p = 0,716; MCS – p = 0,698; QoL = 0,778), wiek (PCS – R = 0,64; p < 0,001; MCS – R = 0,36; p = 0,002; QoL – R = 0,58; p < 0,001), miejsce zamieszkania (PCS – p = 0,273; MCS – p = 0,767; QoL – p = 0,355), wykształcenie (PCS – R = -0,48; p < 0,001; MCS – R = -0,26; p = 0,032; QoL – R = -0,43; p < 0,001), status zawodowy (PCS – p = 0,02; MCS – p = 0,072; QoL = 0,02), rodzaj wykonywanej pracy (PCS – p = 0,911; MCS – p = 0,902; QoL – p = 0,976), warunki socjalno-bytowe (PCS – R = -0,24; p = 0,044; MCS – R = -0,27; p = 0,023; QoL – R = -0,25; p = 0,039), czas trwania choroby (PCS – R = 0,46; p = 0,005; MCS – R = 0,33; p = 0,056; QoL – R = 0,44; p = 0,008), prowadzenie samokontroli (PCS – p = 0,127; MCS – p = 0,382; QoL – p = 0,113), częstość samokontroli (PCS – R = 0,31; p = 0,010; MCS – R = 0,22; p = 0,070; QoL – R = 0,32; p = 0,006), choroby współistniejące (PCS – p < 0,001; MCS – p = 0,001; QoL – p < 0,001). Wnioski. N adciśnienie t ętnicze n egatywnie w pływa n a o cenę j akości życia. Na ocenę jakości życia wpływają: starszy wiek, wyższe wykształcenie, status zawodowy, warunki socjalno-bytowe, dłuższy czas trwania choroby, częstość pomiaru ciśnienia, choroby współistniejące.

EN

Background. Hypertension refers to 9.5 million people between 18 and 79 years of age, which corresponds to 32% of the population. The disease significantly impedes the daily life of the limitations associated with the severity of symptoms, the treatment process and the factors that influence the quality of life. Objectives. Quality of life assessment of patients with hypertension and to investigate the factors that affect the results. Material and methods. The study was carried out among 70 patients (39 women and 31 men) from January to May 2014. The study used an analysis of medical records of patients and a questionnaire to assess the overall quality of life of the SF-36 (Short Form-36). Results. Examined correlations of individual groups of variables to measure physical component sumary (PCS), mental component sumary (MCS) and general QoL index: gender (PCS – p = 0.716; MCS – p = 0.698; QoL = 0.778), age (PCS – R = 0.64; p < 0.001; MCS – R = 0.36; p = 0.002; QoL – R = 0.58; p < 0.001), place of residence (PCS – p = 0.273; MCS – p = 0.767; p = 0.355; QoL – p = 0.355), education (PCS – R = -0.48; p < 0.001; MCS – R = -0.26; p = 0.032; QoL – R = -0.43; p < 0.001), employment status (PCS – p = 0.02; MCS – p = 0.072; QoL = 0.02), type of work performed (PCS – p = 0.911; MCS, p = 0.902; QoL – p = 0.976), social and living conditions (PCS – R = -0.24; p = 0.044; MCS – R = -0.27; p = 0.023; QoL – R = -0.25; p = 0.039), disease duration (PCS – R = 0.46; p = 0.005; MCS – R = 0.33; p = 0.056; QoL – R = 0.44; p = 0.008), conduct self-control (PCS – p = 0.127; MCS, p = 0.382; QoL – p = 0.113), the incidence of self-control (PCS – R = 0.31, p = 0.010; MCS – R = 0.22; p = 0.070; QoL – R = 0.32; p = 0.006), comorbidities (PCS – p < 0.001; MCS – p = 0.001; QoL – p < 0.001). Conclusions. Hypertension adversely a ffects t he quality of l ife a ssessment. The quality of life is affected by: older age, higher education, professional status, social and living conditions, longer duration of the disease, the frequency of measurement of pressure, comorbidities.

4

Analysis of etiology and treatment methods of epistaxis in adult patients visiting

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Syniec M. , Prygiel J. , Dubielska A. , Taradaj K. , Deja M. D. , Balcerzak J.

Polski Przegląd Otorynolaryngologiczny

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2015

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tom 4(4)

21-26

EN

Introduction: Epistaxis is not only the most commonly seen type of bleeding in laryngological emergency department, but also a frequent reason of visiting this department. It may be a symptom of trivial disorder or serious systemic either chronic disease.Aim of study: The primary objective of this study was to analyze the etiology and treatment methods of epistaxis in adult patients. Material and methods: This was the retrospective study of 574 adult patients who visited the Emergency Department of Otolaryngology in Public Central Teaching Hospital between 1st January and 30th December 2014 because of epistaxis. There were 274 females and 300 males with the mean age of 64,6 years (woman), and 60,3 years (men). Results: 228 patients (39,7%) were chronically treated for hypertension. Blood pressure measurement was performed in 335 patients (58,4%) and elevation over 160 mmHg systolic, or over 95mmHg diastolic took place in 132 cases (22,99%). Other significant factor observed in the study was anticoagulant and antithrombotic drug usage. In 134 cases (22,3%) patients were treated with medicine from this group (the most frequently- acetylsalicylic acid). Other accompanying disorders were: heart failure, atrial fibrillation, diabetes mellitus, other cardio-/cerebro-vascular diseases, COPD, respiratory track infection. The most common intervention in case of epistaxis was nasal packing (Rapid Rhino – 248 patients, Spongostan sponge – 129 patients). Captoprilum was administered in 79 cases (13,8%) to normalize elevated blood pressure. 90 patients (15,6%) required an additional internal medicine consultation. Conclusion: The impaired control of hypertension and treatment with oral anticoagulant (acenocumarol) or antithrombotic drugs (acetylsalicylic acid) were the most common reasons of epistaxis in examined group of patients. The most frequent symptomatic management were packing with Spongostan sponge and Rapid Rhino balloon tampon. Typical anterior nasal tamponade with gauze was much less frequent. The treatment according to the etiology was added if needed.

5

Polymorphism in intron 23 of the endothelial nitric oxide synthase gene (NOS3) is not associated with hypertension.

80%

Derebecka N. , Hołysz M. , Dankowski R. , Wierzchowski M. , Trzeciak W. H.

Acta Biochimica Polonica

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2002

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tom 49

|

nr 1

263-268

EN

Nitric oxide (NO) is synthesised in the vascular endothelium by nitric oxide synthase (NOS3) and is an important factor in the regulation of blood pressure. Impaired synthesis of NO due to mutations in the NOS3 gene is associated with hypertension. To date several allelic variants of the NOS3 gene have been identified and their possible linkage with hypertension investigated. We studied the distribution of genotypes and frequency of alleles of the G11T polymorphism in intron 23 of the NOS3 gene in patients with hypertension and in a control group of healthy individuals. The polymorphism was determined by PCR-RFLP analysis. The distribution of genotypes in the patients with hypertension and in the healthy individuals did not differ significantly from the values predicted from Hardy-Weinberg equilibrium for the general population. No major differences in the distribution of the G11T polymorphism in the patients and healthy individuals were found (P > 0.05).

6

Nadciśnienie tętnicze w ujęciu neuropsychologicznym

80%

Witkowska M. , Naumczyk P. , Jodzio K.

Psychologia-Etologia-Genetyka

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2015

|

tom 31

7-22

PL

Nadciśnienie tętnicze (hypertension, HTN) jest jednym z najbardziej rozpowszechnionych przewlekłych problemów zdrowotnych wśród osób dorosłych w społeczeństwach uprzemysłowionych. Ponad 68 milionów ludzi na świecie ma zbyt wysokie ciśnienie krwi i jedynie 50% spośród nich znajduje się pod kontrolą lekarską. Na uwagę zasługuje obszerność literatury potwierdzająca wpływ czynników behawioralnych, psychologicznych i społecznych na częstość występowania i utrzymania choroby wieńcowej oraz nadciśnienia tętniczego. W ciągu minionych 50 lat szeroko zakrojone badania udokumentowały wpływ stresu i czynników dyspozycyjnych w etiologii obu chorób. Ponadto, coraz częściej podkreślane są te następstwa nadciśnienia tętniczego, które w sposób bezpośredni oddziałują na ośrodkowy układ nerwowy (OUN), a w konsekwencji na szeroko rozumiane funkcjonowanie poznawcze. Niestety przegląd obszernej literatury przedmiotu skłania do wniosku, że problemy neuropsychologiczne osób z HTN rozpatruje się często w nadmiernie wycinkowy sposób. Artykuły w głównej mierze koncentrują się na tradycyjnych aspektach psychosomatycznych choroby, takich jak emocje czy stres, a pomijają potencjalne konsekwencje poznawcze HTN. Funkcjonowanie ośrodkowego układu nerwowego rozpatruje się wyłącznie na tle chorób naczyniowych mózgu. W rezultacie niedocenia się negatywnego wpływu HTN na funkcjonowanie ośrodkowego układu nerwowego, a tym samym na przedwczesny proces starzenia się mózgu, którego wyrazem są naczyniowe ograniczenia poznawcze. Z tego powodu treść niniejszego artykułu koncentrując się przede wszystkim na współczesnych badaniach, podsumowuje bieżącą wiedzę na temat behawioralnych, psychologicznych i mózgowych korelatów chorób układu sercowo-naczyniowego, ze szczególnym uwzględnieniem nadciśnienia tętniczego.

EN

Hypertension (HTN) is one of the most prevalent chronic health problems among adults in industrialized societies. More than 68 million people worldwide have high blood pressure, and only 50% of them are under medical supervision. Noteworthy is voluminous literature confirming the impact of behavioral, psychological and social factors on the incidence and maintenance of coronary artery disease and hypertension. Over the past 50 years, extensive research has documented the impact of stress and dispositional factors in the etiology of those both diseases. The consequences of high blood pressure, which directly affect the central nervous system, and thus the cognitive functioning, are emphasized. Unfortunately, a comprehensive review of the literature leads to the conclusion that the neuropsychological problems of patients with HTN are insufficiently highlighted. Articles mainly focus on the traditional aspects of psychosomatic issues, such as emotions or stress, and ignore the potential cognitive consequences of HTN. The functioning of the central nervous system is considered in context of various cerebrovascular diseases. Consequently, the negative impact of the HTN on functioning of the central nervous system as well as premature ageing of the brain reflected by vascular cognitive impairment are underestimated. The content of this article focuses primarily on contemporary research. It also summarizes the current knowledge about the behavioral, psychological and brain correlates of dysfunctions of the cardiovascular system, with a particular emphasis on hypertension.

7

Surface structure changes of pathological placenta tissue observed using scanning electron microscopy - a pilot study

80%

Bobiński R. , Pielesz A. , Waksmańska W. , Sarna E. , Ulman-Włodarz I. , Kania J. , Mikulska M. , Turbiarz A.

Acta Biochimica Polonica

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2017

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tom 64

|

nr 3

533-535

EN

Structural changes within the placenta are observed in the course of pathological pregnancy. The aim of the study was to perform initial assessment of morphological features of placenta. The analysis was conducted by Scanning Electron Microscopy. Samples of placenta of women who delivered neonates appropriate for gestational age were characterized by a homogenous surface texture with natural corrugation. The surface of IUGR placenta from the group of mothers with pregnancy induced hypertension was definitely heterogeneous - noticeable swelling of tissue surface was observed. Samples from LGA group also demonstrated a number of surface bulges and heterogeneities which were, nonetheless, characterized by a certain repeatability.

8

The Prevalence of Arterial Hypertension among Students of West Pomeranian Voivodeship

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Umiastowska D. , Żółtowska H.

Central European Journal of Sport Sciences and Medicine

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2015

|

tom 11

|

nr 3

81-86

EN

The research was carried out as part of the research project N N 404 260335 “The lifestyle of children and adolescents and their level of athleticism, fitness and somatic development” during Crampton test in 2633 students of elementary, secondary and high schools in West Pomeranian Voivodeship. 214 subjects, that is 8.1% of the whole group, were qualified for the group with the hypertension. The arterial hypertension was reported in 7.9% of girls and 8.4% of boys. The statistically significant dependencies between the prevalence of arterial hypertension and the size of metropolitan area where the children and adolescents live, as well as their sex were observed.

9

Effects of L-Arginine Supplementation on Blood Pressure Reduction Pre-, Peri-, and Post-Cardiovascular Stimulus in Hypertensive Subjects with Different Angiotensin-Converting-Enzyme Genotypes

80%

Malfatti C. R. M. , Pavlak J. L. L. , da Silva L. A. , Medeiros T. E. , Alonso K. C. , Artoni R. F. , Nogaroto V. , Túrmina J. A. , Osiecki A. , Osiecki R.

Human Movement

|

2014

|

tom 15

|

nr 2

116-119

EN

Purpose. The present study investigated whether L-arginine supplementation reduces blood pressure (BP) in hypertensive subjects with different ACE genotypes. Methods. Eight male hypertensive patients received L-arginine (2 or 4 g/day) or a placebo for a period of 4 days prior an exercise test. Statistical analysis consisted of one-way analysis of variance. Results. L-arginine supplementation induced a statistically significant (p ⋋ 0.05) reduction in systolic BP measured during rest (reductions of 7.8% and 12.3% with 2 and 4 g/day, respectively), exercise (reductions of 11.8% and 10.4% with 2 and 4 g/day, respectively), and recovery (reductions of 11.7% and 10.7% with 2 and 4 g/day, respectively). The observed magnitude of BP reduction suggests an association with ACE polymorphism; a larger effect was seen with the II and DI genotypes compared with the DD genotype (II: 121 mmHg and DI: 133 mmHg vs. DD: 144 mmHg). Conclusions. The results showed that L-arginine supplementation at low doses was efficient in reducing BP and that vasodilator actions that occurred through the secretion of nitric oxide might be ACE genotype dependent.

10

HIGH INTENSITY STRENGTH TRAINING IN OVERWEIGHT ADULTS IN THE WORKPLACE: A PILOT STUDY

80%

Borràs P. A. , Vidal-Conti J. , Palou P.

Journal of Physical Education & Health - Social Perspective

|

2016

|

tom 5

|

nr 7

35-42

XX

The aim of this pilot study was to determine (a) the effects of high intensity strength training in the workplace on blood pressure, fat percentage and physical fitness in overweight adults, and (b) the influence of this intervention on the blood pressure in a subsample of hypertensive subjects. Overweight adults (n=15) aged 42.8 years underwent anthropometric assessment (weight, fat percentage, waist circumference, and triceps skinfold), physical fitness assessment (leg extensor power, upper body endurance, hand grip strength and Vo2max) and blood pressure assessment before and after 8 weeks of high intensity resistance training in the workplace. Each training session consisted of 16 sets of 45 repetitions performed at 1 repetition per second, decreasing load at the point of muscular failure starting at 60% of repetition maximum (RM). The effects of the intervention were analyzed by paired sample t-tests. For exploratory purposes, a non-parametric test was also performed (Wilcoxon matched-pair signed-rank) to examine if this decision could affect the results. Weight, body fat percentage, and triceps skinfold decreased significantly with the high intensity resistance training protocol in the workplace (all P<0.05). Performance in physical fitness tests increased significantly with training (all P<0.05), except for handgrip strength. Both systolic and diastolic blood pressure decreased significantly with R-HIRT in the workplace (all P <0.05) in hypertensive subjects (n=10). This protocol performed in the workplace in this pilot study produces health and fitness benefits in overweight and hypertensive people.

11

Detrimental effects of early rural life on blood pressure among urban male migrants in Wrocław, Poland

80%

Kozieł S. , Lipowicz A. , Ulijaszek S. J.

Anthropological Review

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2012

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tom 75

|

nr 2

83-91

EN

The purpose of the study was to compare the blood pressure of rural-to-urban migrants and the sedentary population (non-migratory) of the city of Wrocław, Poland. Additionally, the effect of time spent in the rural area on blood pressure was also assessed. The study sample consisted of 2753 males aged 25-75 years, following a medical examination, underwent an interview and anthropometric measurements between 1989-90. Based on the place of origin all males were divided into rural-to-urban migrant inhabitants of Wrocław (N=1222) and sedentary inhabitants of Wrocław (N=921). The percentage of time spent in the rural area [(time spent in rural area/age)*100] was then calculated and was used in analysis. In each age category, the rural-urban migrants were found to be shorter in height. Age, BMI, level of education and time of migration had a significant effect on both the systolic and diastolic blood pressure irrespective of the level of education. It was demonstrated that the time of migration, allowing for age, body size and education level, significantly correlated with blood pressure. The later in time, the males migrated from rural to urban areas, the higher their blood pressure. It was hypothesized that unhealthy behavior could still have continued in a new urban environment, resulting in migrant - sedentary differences in health parameters.

12

Impedance cardiography – optimization and efficacy evaluation of antihypertensive treatment

80%

Panasiuk-Kamińska K. , Szeliga-Król J. , Jaroszyński A.

Family Medicine & Primary Care Review

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2016

|

nr 3

321-324

13

Phytotherapy as an alternative method to supp ort treatment of hypertension

80%

WYKURZ P. , MUSZYŃSKA B.

Medicina Internacia Revuo

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2017

|

tom 28

|

nr 108

202-215

EN

Hypertension is a dangerous chronic disease; it is the most common cause of death in Poland, Europe and the United States. In Poland, the estimated number of people with hypertension is about 36%. The development of this disease is progressive, a large proportion of people are unaware of their disease in the early stages. The use of basic recommendations for the prevention of hypertension i. e. stopping smoking, limiting alcohol intake and weight gain, increasing physical activity, limiting salt intake and changing eating habits can effectively lower blood pressure by 20-50 mm Hg. Such a considerable effect can significantly help a person with grade 2 hypertension (160-179 / 100-109 mm Hg). Phytotherapy is the branch of medicine that uses plants for medicinal purposes. Active compounds contained in plant raw materials can be used in heart and vascular diseases. They exhibit anti-arrhythmic, hypotensive, dilate peripheral, cerebral, coronary vessels, improving lipid profile, antioxidant, vasoprotective, antiplatelet, anti-inflammatory, immunostimulatory and diuretic. They exhibit negative chronotropic, but dromotropic and inotropic positive activity. Phytotherapy can be used as an alternative method to support the treatment of hypertension. In combination with basic preventive recommendations, it can delay the treatment by synthetic drugs for a very long time. It is therefore worth using herbs and their blends to improve the quality of our lives.

14

Acute Cardiovascular Alterations in Hypertensive Renal Patients During Exercise with Constant Load in the Interdialytic Period

80%

Malfatti C. , Ferreira S.

Human Movement

|

2010

|

tom 11

|

nr 2

157-161

EN

Purpose. The study investigated acute cardiovascular alterations during aerobic exercise in interdialytic phase. Basic procedures. Seven hypertensive men with chronic renal disease (CRD) and seven healthy men (C) were matched according to the age (CRD: 48.5 ± 8.5; C: 45.28 ± 9.3) and body mass index (CRD: 24.2 ± 2.8 kgm-2; C: 26.7 ± 2.7 kgm-2). The exercise was executed on a cycloergometer during 6 minutes at 75% of HRmax and 3 minutes of recovery without load at 55 - 60 rpm. The patients came twice and were controlled only on an occasion at the hospital at 9.00 am. The exercise was performed before and 24 hours after haemodialysis (HD). The blood samples were drawn immediately before and 24 hours after HD for hematocrit and hemoglobin analysis. The statistical difference was verified by the ANOVA and two-tailed unpaired Student's t-test only for p < 0.05. Main findings. After HD, the systolic blood pressure (SBP) shows reduction in the first stage (~14%; p < 0.05) and in the recovery period of exercise (~18%; p < 0.05). A hypotension effect of HD was better observed in the diastolic blood pressure (DBP) from the 5th to 9th min of exercise (~20%; p < 0.05). The HD did not modify biochemical (hematocrit and hemoglobin), physiological (Rest SpO2; rest SBP; rest DBP and VO2max) and body weight parameters. Conclusions. The study showed a significant reduction in blood pressure levels during the exercise, principally in DBP 24 hours after HD, suggesting that exercise executed during this period can induce better tolerance to exercise in dialyzed patients.

15

Arterial hypertension as a factor in the choice of conflict resolution strategies by elderly persons

80%

Tikhonova N. , Demina N. , Klimatckaia L. , Osipov A. , Kudryavtsev M. , Zhavner T. , Shpakou A.

Family Medicine & Primary Care Review

|

2018

|

nr 4

368-372

16

Some approaches to improving patients’ compliance with antihypertensive pharmacotherapy

80%

Vdovichenko V. , Snezhitskiy V. , Kazakiewicz D.

Progress in Health Sciences

|

2011

|

tom 1

|

nr 1

27-33

EN

Purpose: The purpose of this work was to investigate the impact of usage of a computer program PharmCalculation in the polyclinic on the patients’ compliance. Material and methods: Study group was included 73 AH outpatients whose physicians have been provided with the computer program PharmCalculation. Treatment patterns were observed during two-month period. Afterwards patients were surveyed in order to investigate compliance. Control group consisted of 100 randomly chosen customers of drugstores who were buying antihypertensives. Survey was performed in order to investigate their compliance. Results: 80.8% of patients in the study group were taking antihypertensive drugs regularly. In the Control group, there were 60% of patients who took antihypertensives regularly. Odds' ratio of adherence to treatment was 2.8 in the favor of the study group (95% interval –1.4-5.8). There was an evidence, that usage of antihypertensive drugs in median therapeutic doses raised adherence of patients in the study group to the prescribed pharmacotherapy (p=0.019). Odds' ratio was 4.4 in the favor of usage of median therapeutic doses with 95% confidence interval 1.1-21.8. Conclusion: There is evidence that usage of software PharmCalculation in the polyclinic may improve compliance among hypertensive outpatients.

17

Comparison between bioelectrical impedance analysis and anthropometric indices in hypertensive patients

80%

Krzesiński P. , Rozbicki P. , Pałkowska-Goździk E. , Banak M.

Pediatria i Medycyna Rodzinna

|

2018

|

tom 14

|

nr 3

301-305

EN

Aim: Obesity is one of the most crucial challenges of contemporary medicine. Bioelectrical impedance analysis is a useful tool to identify individuals with increased fat mass. However, the equipment is relatively expensive, especially compared to basic anthropometric methods. The aim of this study was to evaluate the relations between anthropometric indices and bioelectrical impedance analysis in patients with uncomplicated arterial hypertension. Material and methods: In 137 hypertensives the correlations between fat mass (absolute, FM; relative, %FM) and anthropometric parameters (body mass index, BMI; waist circumference, WC; waist-to-hip ratio, WHR; waist-to-height ratio, WHtR; body adiposity index, BAI; visceral adiposity index, VAI) were analysed. Results: Classic anthropometrics correlated well with bioimpedance indices of adipose tissue content: %FM vs. BAI (R = 0.77), WHtR (R = −0.54), BMI (R = 0.52), WC (R = 0.29); FM vs. BMI (R = 0.82), WC (R = 0.66), BAI (R = 0.58), VAI (R = 0.26), WHtR (R = 0.23), WHR (R = 0.19). In females BMI, WC and BAI showed the strongest correlations with adiposity. In males they were WHtR and WC. Conclusions: Some anthropometric measurements show good agreement with bioelectrical impedance analysis and can be considered a valid surrogate for body composition assessment in the case of its inaccessibility. In hypertensive women WC and BMI seem to be the most precise in the assessment of %FM, while in men WHtR and WC are more useful.

PL

Cel: Otyłość należy do głównych wyzwań współczesnej medycyny. Analiza bioimpedancyjna stanowi użyteczne narzędzie identyfikacji osób ze zwiększoną masą tkanki tłuszczowej. Niestety, sprzęt do analizy bioimpedancyjnej jest dość kosztowny, zwłaszcza w porównaniu z podstawowymi metodami antropometrycznymi. Celem pracy była ocena związku pomiędzy pomiarami antropometrycznymi a analizą bioimpedancyjną u pacjentów z niepowikłanym nadciśnieniem tętniczym. Materiał i metody: U 137 osób z nadciśnieniem tętniczym oceniono korelacje między ilością tkanki tłuszczowej (bezwzględnej, fat mass, FM; względnej, %FM) a parametrami antropometrycznymi (wskaźnik masy ciała, body mass index, BMI; obwód talii, waist circumference, WC; wskaźnik talia–biodra, waist-to-hip ratio, WHR; wskaźnik talia–wzrost, waistto-height ratio, WHtR; wskaźnik otłuszczenia ciała, body adiposity index, BAI; wskaźnik wisceralnej – trzewnej tkanki tłuszczowej, visceral adiposity index, VAI). Wyniki: Klasyczne pomiary antropometryczne korelowały z bioimpedancyjnymi wskaźnikami zawartości tkanki tłuszczowej: %FM vs BAI (R = 0,77), WHtR (R = −0,54), BMI (R = 0,52), WC (R = 0,29); FM vs BMI (R = 0,82), WC (R = 0,66), BAI (R = 0,58), VAI (R = 0,26), WHtR (R = 0,23), WHR (R = 0,19). U kobiet najsilniejszy związek z ilością tkanki tłuszczowej wykazywały BMI, WC i BAI, zaś u mężczyzn – WHtR i WC. Wnioski: Niektóre pomiary antropometryczne wykazują wysoką zgodność z analizą bioimpedancyjną i mogą być brane pod uwagę jako zastępcze wskaźniki oceny składu ciała w przypadku braku możliwości jej zastosowania. U kobiet z nadciśnieniem tętniczym najbardziej precyzyjne w ocenie %FM okazują się WC i BMI, podczas gdy u mężczyzn są to WHtR i WC.

18

Gastrointestinal neuroendocrine cells in various types of hypertension – a review

80%

Niezgoda M. , Kasacka I.

Progress in Health Sciences

|

2017

|

tom 7(2)

117-125

EN

Recent years have witnessed a progressive increase in the number of people suffering from hypertension, which is one of the most serious health problems in the world. Hypertension results in changes leading to function disorders, not only of the organs and tissues, but also changes leading to the activation of many defense mechanisms in the cells in order to prevent damage. One of them is the expression of neuroendocrine (NE) hormones and biologically active substances, which has been the focus of extensive research for a number of years. Active involvement of NE cells and the biological and therapeutic properties of various substances synthesized by them have been confirmed in clinical trials and in various experimental models. Results obtained in many research studies indicate intense activity of enteroendocrine cells in the gastrointestinal tract in various pathological conditions, including hypertension. In the present review, we discuss the morphological and functional changes of gastrointestinal neuroendocrine cells under conditions of different types of hypertension.

19

The seven-year epidemiological study of legal abortion caused by heart disease, blood disorders, diabetes and hypertension as referred to forensic medicine centers in Fars Province

70%

Ghodrati F. , Saadatmand N. , Gholamzadeh S. , Akbarzadeh M.

Family Medicine & Primary Care Review

|

2019

|

nr 1

23-29

EN

common risk factors for high risk pregnancies and spontaneous or therapeutic abortions. Objectives. To investigate the legal abortion caused by heart disease, blood disorders, diabetes and hypertension as referred to forensic medicine centers in Fars Province from 2007 to 2013. Material and methods. In a retrospective, cross-sectional study, samples consisted of all documents of people referred to forensic medicine centers in Shiraz since 2007 to 2013, comprising of 1664 files. Data collection tools included a demographic forum and the checklist of abortion causes. SPSS.16.0 was applied to analyze the data through descriptive statistical analysis. Results. The most frequent age group was 25–29 years at 31.5% (n = 522) and the lowest was over 40 years old at 4.15% (n = 70). The statistical report of the reasons for legal abortion permission were 19% (n = 63), 24.4% (n = 81), 10.54% (n = 35), and 8.13% (n = 27) due to heart problems, blood disorders, hypertension, and diabetes mellitus, respectively. Most frequent legal abortion permits by forensic medicine due to maternal causes were between the years of 2011–2012 at 17.8–28% (n = 59–93). The relationship between legal abortion permission at The Forensic Medicine Center at different years and maternal ages was statistically significant (p < 0.00001). Conclusions. The most common prevalent reason of abortion was Blood Disorder – 81 patients (24.4%) and heart disease – 63 cases (19%). It is essential that family education and prevention of repeated pregnancies be done with high-risk women. Also, initiation of pregnancy care at lower gestational age in identifying risky pregnancies and timely control of complications must also be undertaken

20

The prevalence of cardiovascular disease risk factors in normotensive, pre-hypertensive and hypertensive South African colliery executives

70%

Grace J. , Semple S.

International Journal of Occupational Medicine and Environmental Health

|

2012

|

tom 25

|

nr 4

375-382

EN

Objective: The aim of this study was to establish the prevalence of cardiovascular disease (CVD) risk factors amongst South African colliery executives presenting normal blood pressure (normotensive), pre-hypertension and hypertension. Materials and Methods: Selected CVD risk factors of a non-randomized, available population of 143 Caucasian male executives from fi ve South African collieries situated in Mpumalanga and Gauteng Provinces were recorded. Results: Executives with pre-hypertension and hypertension exhibited a higher prevalence of CVD risk factors, compared to the persons with normal blood pressure levels. The percentage of executives with CVD risk factors, with the exception of BMI, was greater amongst those with pre-hypertension than those with hypertension. Conclusion: The current study showed that a workplace CVD risk screening process was effective in identifying the relatively high prevalence of CVD risk factors amongst SA colliery executives. In addition, out of all the studied risk factors, undesirable body composition (BMI, WHR and fat %) exhibited the highest prevalence amongst pre-hypertensive and hypertensive SA colliery executives.