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Charakterystyka i zastosowanie hydrodynamicznego ogniskowania strugi cieczy w mikrokanałach

100%

Domagalski P. , Dziubiński M. , Mielnik M. M. , Saetran L. R.

2006

tom Nr 6s

53-54

The article presents characteristics of the hydrodynamical focusing accompanied by a review of possible applications. The dependence of the focused sheet position on side stream velocities and the dependence of the sheet curvature on its position in the outlet channel are presented and discussed. The results enable one to conclude that the application of hydrodynamical focusing in reaction engineering is highly profitable.

X-ray microdiffraction on flow-controlled biomolecular assemblies

75%

Evans H. M. , Dootz R. , Köster S. , Pfohl T.

2007

tom Vol. 55, nr 2

217-227

The study of liquid crystalline assemblies, with an emphasis on biological phenomena, is now accessible using newly developed microdevices integrated with X-ray analysis capability. Many biological systems can be described in terms of gradients, mixing, and confinement, all of which can be mimicked with the use of appropriate microfluidic designs. The use of hydro-dynamic focusing creates well-defined mixing conditions that vary depending on parameters such as device geometry, and can be quantified with finite element modelling. We describe experiments in which geometry and strain rate induce finite changes in liquid crystalline orientation. We also demonstrate the online supramolecular assembly of lipoplexes. The measurement of lipoplex orientation as a function of flow velocity allows us to record a relaxation process of the lipoplexes, as evidenced by a remarkable 4-fold azimuthal symmetry. All of these processes ale accessible due to the intentional integration of design elements in the microdevices.