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1
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EN
Finnish sauna is one of the most popular among all the saunas types and as a result is the most commonly used. Bath in the Finnish sauna is a combination of heating with a warm and dry air and the short influence of high humidity and cooling with cold water and air. The article aims to identify pulse and blood pressure in the conditions of thermal heating in the sauna among women and men between the age of 20-25. Hypothetically sauna has a great influence on the basic hemodynamic parameters such as pulse and blood pressure. There were 127 healthy, young women and 74 men, students at the University of Physical Education in Wroclaw taking part in the experiment. Average age of the volunteers was 21.5 and 21.7.The results indicate that a bath in the Finnish sauna leads to a significant increase of the pulse among men and women. Concurrently the results show a considerable decrease in diastolic pressure, with the systolic pressure remaining at almost the same level. It can be concluded that a bath in a Finnish sauna positively influences the hemodynamics of blood pressure and pulse. A series of bathes in the Finnish sauna leads to a considerable decrease of the systolic and diastolic pressure and an increase of the pulse among male and female volunteers.
EN
Our previous study showed a significant relationships between static exercise-induced changes in plasma adrenomedullin (ADM) and those in endothelin-1 (ET-1), noradrenaline (NA) and pre-ejection period/left ventricular ejection time ratio (PEP/LVET) in older healthy men. It is hypothesized that ADM, ET-1, NA and adrenaline (A) may function as endogenous regulators of cardiac function by modulating myocardial contractility during static exercise. The present study was undertaken to assess the relationships between exercise-induced changes in plasma ADM, ET-1, NA, A concentrations and those in ascending aortic blood flow peak velocity (PV) and mean acceleration (MA) measured by Doppler echocardiography in 24 healthy older men during two 3-min bouts of handgrip at 30% of maximal voluntary contraction, performed alternately with each hand without any break between the bouts. Plasma ADM, ET-1, NA and A as well as heart rate (HR), blood pressure (BP), PV and MA were determined. During handgrip, plasma ADM, ET-1, NA and A as well as HR, BP increased, whereas PV and MA decreased. The increases in plasma ADM correlated positively with those in ET-1, NA and diastolic BP, and correlated negatively with changes in PV (r = -0.68) and MA (r = -0.62). The increases in plasma ET-1 correlated positively with those in NA and BPs and correlated negatively with changes in PV (r= -0.67) and MA (r= -0.60). The results of this study suggest that in healthy older men the exercise-induced changes in plasma ADM, ET 1 and catecholamines are related to alterations in left ventricular contractile state and may co-operatively counteract age-related deterioration of cardiac performance in men.
EN
A software package for the simulation of the cardiovascular system and of artero-ventricular interaction has been developed. It includes the reproduction of the effects of mechanical circulatory like Left Ventricular Assist Device (LVAD), Biventricular Assist Device (BVAD), Intra-aortic Balloon Pump (IABP) and ventilatory support systems. Lumped parameters models were used to reproduce the circulatory phenomena in terms of pressure and volume relationships. Variable elastance models reproduce the Starling's law of the heart, for each ventricle. LVAD and BVAD are inserted with atrial-arterial cannulation and can be synchronised with the onset of the natural ventricle systole. IABP model, inserted in the arterial tree, is considered as a flow source. Controlling the level of thoracic pressure (Pt) performs the simulation of mechanical ventilation. The examples of simulations are presented in the paper as the effects of LVAD and mechanical ventilatory support on circulatory system, in terms of hemodynamic parameters changes.
PL
W artykule przedstawiono model komputerowy CARDIOSIM@ i oprogramowanie do symulacji zależności hemodynamicznych w układzie sercowo-naczyniowym na komputerze zgodnym z PC. Oprogramowanie to umożliwia także symulację wpływu różnych metod mechanicznego wspomagania krążenia, np. sztucznej lewej komory serca (LVA]), wspomagania dwukomorowego (BVAD), lub pompy wewnątrzaortalnej (lABP) i oddychania na parametry hemodynamiczne i energetyczne. Modele LV AD, BVAD i IABP są zsynchronizowane z pracą naturalnej lewej komory serca (z początkiem fazy systolu). LVAD i BVAD są umieszczone równolegle z komorami serca, a IABP jest traktowane jako źródło przepływowe w tętniczej części modelu. Regulacja poziomu średniego, dodatniego ciśnienia w klatce piersiowej w modelu oddaje wpływ sztucznej wentylacji płuc na układ sercowo-naczyniowy. Model komputerowy opisujący zależności ciśnieniowo-przepływowe w poszczególnych częściach układu sercowo-naczyniowego jest modelem liniowym o staIych skupionych. Do opisu własności każdej z komór serca wg prawa Starlinga wykorzystano model zmiennej elastancji. W pracy przedstawiono przykłady symulacji komputerowej, jako cenną możliwość przewidywania wpływu stosowania LVAD i wspomagania oddychania na hemodynamikę.
4
72%
EN
In the paper some problems concerning investigations conducted at Bioflows Departament of the Institute of Biocybernetics and Biomedical Engineering on cardiovascular , respiratory and veno-lymphatic assistance have been discussed. The investigations were mainly focused on modelling of cardiovascular and respiratory systems, cardiopulmonary interaction and veno-lymphatic non-invasive support. The results of physical and computer simulation of cardiopulmonary assistance and clinical results of veno-lymphatic support studies have been presented.
EN
Cardiac Resynchronization Therapy (CRT) seems to be the most encouraging treatment to limit the damages of ventricular remodelling in patients with moderate-severe cardiac insufficiency. Mathematical modelling of the cardiovascular system is a tool potentially useful to understand how the Biventricular Pacemaker (BPM) must be synchronised during CRT. In this work a computer simulator reproduces clinical data measured, on different patients affected by asynchronous ventricular contraction, before and after CRT. Three patients, affected by asynchronous ventricular contraction, were monitored before and after biventricular stimulation through CRT. Measured and simulated data were compared. Results show that the software simulator can well reproduce in vivo data. Besides, simulated results from BPM together with drug therapy are in accordance with literature data. Numerical modelling could be a useful tool to optimize the BPM synchronization.
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