Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

3 Polish Journal of Chemistry

Znaleziono wyników: 3

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: glycopeptides

Sortuj według:

Ogranicz wyniki do:

Lysine-Vasopressin Analogues with Glycoconjugates in Position 8

100%

Marcinkowska A. , Borovickova L. , Slaninova J. , Grzonka Z.

2006

tom Vol. 80, nr 5

759-766

Two analogues of lysine-vasopressin in which the lysine side chain was modified by the attachment of glucuronic acid through the amide bond were synthesized and their pharmacological properties evaluated. In comparison to arginine-vasopressin used as a standard, both analogues were found to exhibit low activity in vasopressor test, moderate activity in antidiuretic test, and comparable activity in uterotonic test.

Carbohydrate Chains and Their Binding Sites in Mistletoe Lectin I

100%

Stoeva S. , Maier T. , Soler M. , Voelter W.

tom vol. 73 nr 1

125-133

The carbohydrate moieties, linked to mistletoe lectin 1 (ML-1) are characterized by enzymatic digestion of the individual A and B chains (MLA and MLB), HPLC separation of the (glyco)peptide digests and their sequence and mass spectrometric analysis. All carbohydrate chains are linked via Asn residues to the MLA protein molecule. A xylomannose-type oligosaccharide (1) structure (Man3Xyl1Fuc1GlcNac2) is attached to the Asn112 residue of the A chain. Three different glycosylation sites are identified for the B chain: oligosaccharide II (Man6GlcNac2) is found to be linked to Asn96 as well as Asn136 residues. In homologous mistletoe lectins, isolated from different harvest batches, oligosaccharide III (Man5GlcNac2) is attached to Asn136 instead of oligosaccharide II**.

Total Synthesis of the Nephritogenoside Glycopeptide

100%

Zhang H. , Wang Y. , Thurmer R. , Al-Qawasmeh R. , Voelter W.

tom vol. 73 nr 1

101-115

A mild three-dimensional orthogonal protection scheme, based on Nps/Fmoc-groups for a-amino, benzyl residues for hydroxyl and carboxyl protection and 2-chlorotrityl esters as anchoring linkage proved to be a new effective approach for the synthesis of glycopeptides. The oligosaccharide moiety of the nephritogenoside glycopeptide is conveniently assembled via phenyl thioglycosides as glycosyl acceptors and phenyl thioglycosyl sulfoxides as donors, readily accessible from the thioglycosides by oxidation with m-chloroperbenzoic acid.