Chosen aspects from the important role of adhesives in the production of lightweight panels was presented. Components of lightweight panels and particular adhesives basis on poly(vinylacetate)-PVAC, polyurethane (PUR) prepolymer, and reactive hot melt (HM) used in production and their characteristic was described. For the production of lightweight panels are used a various adhesives such as PVAC dispersion, products based on PUR prepolymers, and particular reactive PUR HM systems. Kind of adhesives influenced upon the properties of obtain joints im lightweight panels and their functionality and stability. Comparison of various methods of lightweight panels production. Given some economic aspects of production of lightweight panels, using various adhesives and methods of their application.