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Organization of the Drosophila genome

100%

Jullien N. , Henaut A. , Miassod R.

Cellular and Molecular Biology Letters

1999

tom 04

nr 4

The distribution of (A,T)-rich regions has been investigated on a 835kb DNA fragment (D835), from the Drosophila X sex chromosome, unsequenced but provided with detailed physical maps for restriction enzymes-recognizing (A,T)- or (C,G)- or (mixte)-motifs, and on several sequenced DNA fragments, 100-600 kb long, from the autosomal chromosomes. Numerous (A,T)-rich regions are present in all DNA fragments. Their size varies from 0.2 kb to several kb in all cases, except for D835 where some of them extend to 20-30 kb. The relationship between these (A,T)-rich regions and several chromosome landmarks has been examined in the particular case of D835. Topo II in-vitro sites are randomly distributed with regard to (A,T)-richness. However, transcription units and repeated regions are significantly localized outside (A,T)-rich regions. On the opposite, SARs and ARSs are mostly localized within (A,T)-rich regions. Lastly, topo II in-vivo sites are almost exclusively localized in (A,T)-rich regions. Speculations are proposed on why and how (A,T)-rich regions may have appeared during the emergence of Drosophila genome from a primitive genome.

The model plant Arabidopsis thaliana: Implications from analysis of gene redundance to genome functional plasticity

88%

Sadowski J. , Babula D. , Kaczmarek M. , Ziolkowski P. , Stanko A.

Polish Journal of Natural Sciences. Supplement

2003

tom 01

Animal coronaviruses in the light of COVID-19

75%

Domanska-Blicharz K. , Wozniakowski G. , Konopka B. , Niemczuk K. , Welz M. , Rola J. , Socha W. , Orlowska A. , Antas M. , Smietanka K. , Cuvelier-Mizak B.

Journal of Veterinary Research

2020

tom 64

nr 3

Chlamydiae – what’s new?

75%

Zareba-Marchewka K. , Szymanska-Czerwinska M. , Niemczuk K.

Journal of Veterinary Research

2020

tom 64

nr 4

Brachypodium distachyon – a model plant to study grass genome structure, dynamics and evolution

63%

Idziak D. , Hasterok R. , Betekhtin A. , Borowska-Zuchowska N. , Braszewska-Zalewska A. , Chwialkowska K. , Gorkiewicz R. , Kus A. , Kwasniewska J. , Kwasniewski M. , Robaszkiewicz E. , Siwinska D. , Wolny E. , Chrominski K. , Tkacz M.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

2015

tom 96

nr 1

The human genome structure and organization

63%

Makalowski W.

Acta Biochimica Polonica

2001

tom 48

nr 3

Genetic information of human is encoded in two genomes: nuclear and mitochondrial. Both of them reflect molecular evolution of human starting from the beginning of life (about 4.5 billion years ago) until the origin of Homo sapiens species about 100000 years ago. From this reason human genome contains some features that are common for different groups of organisms and some features that are unique for Homo sapiens. 3.2 X 10 base pairs of human nuclear genome are packed into 23 chromosomes of different size. The smallest chromosome - 21st contains 5 X 10 7 base pairs while the biggest one -1st contains 2.63 X 10 8 base pairs. Despite the fact that the nucleotide sequence of all chromosomes is established, the organisation of nuclear genome put still questions: for example: the exact number of genes encoded by the human genome is still unknown giving estimations from 30 to 150 thousand genes. Coding sequences represent a few percent of human nuclear genome. The majority of the genome is represented by repetitive sequences (about 50%) and noncoding unique sequences. This part of the genome is frequently wrongly called "junk DNA". The distribution of genes on chromosomes is irregular, DNA fragments containing low percentage of GC pairs code lower number of genes than the fragments of high percentage of GC pairs.

Molecular cytogenetic analysis of genome structure in Chenopodium album complex

63%

Kolano B. , Siwinska D. , Maluszynska J.

Seria Biologiczna. Uniwersytet im. Adama Mickiewicza w Poznaniu

2005

tom 72

On heterochromatin in karyosystematic studies

63%

Joachimiak A. , Kula A. , Grabowska-Joachimiak A.

Acta Biologica Cracoviensia. Series Botanica

1997

tom 39

The application of chromosome banding methods for plant karyosystematic studies is analyzed. The authors discuss ways of constructing C-band idiograms and interpretating the results of C-banding studies with respect to the polymorphism of heterochromatin and its histochemical differentiation. The role of quantitative changes of heterochromatin in evolution, its functional effect, and the division into dispensable and indispensable heterochromatin are presented. An overview of the recent literature on this subject is also given.