Wyniki wyszukiwania - Biblioteka Nauki

1

The impact of renal function on clinical and biochemical characteristics in advanced heart failure patients

100%

Bohdan M. , Frankiewicz A. , Gruchała M.

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2019

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tom 1

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nr 2

17-22

EN

Background: Coexistence of heart failure with reduced ejection fraction (HFrEF) and chronic kidney disease is associated with poor prognosis. We assessed the effect of renal function on exercise capacity and clinical parameters of patients with HF. Material and methods: Forty five patients aged 58.2 ± 10.6 years with stable severe HFrEF were recruited. Patients were divided into 3 groups: group 1 - eGFR: 30-59 ml/min/1.73 m2; group 2 - eGFR: 60-89 ml/min/1.73 m2 and group 3 - eGFR: ≥90 ml/min/1.73 m2. Biochemical analysis, echocardiography, 6-minute walking test and cardiopulmonary stress testing were performed. Results: Patients in group 1 were significantly older than patients in group 3 (60.4 ± 11.1 years vs. 49.25 ± 11.2 years, respectively, p<0.05). Patients in group 2 had significantly higher BMI in comparison to group 3 (29.8 ± 4.4 vs. 25.1 ± 4.2; p<0.05). Interestingly, patients in group 1 had significantly lower peak oxygen uptake (10.2 ± 3.1 ml/kg/min vs. 16.1 ± 3.5 ml/kg/min, p<0.05) and oxygen uptake at anaerobic treshold (7.9 ± 2.4 ml/kg/min vs. 10.7 ± 1.9 ml/kg/min, p<0.05). Conclusions: Diminished renal function in patients with stable, advanced HFrEF may be associated with significantly worse peak VO2 and VO2 in AT.

2

The impact of renal function on clinical and biochemical characteristics in advanced heart failure patients

100%

Bohdan M. , Frankiewicz A. , Gruchała M.

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nr 2

17-22

EN

Background Coexistence of heart failure with reduced ejection fraction (HFrEF) and chronic kidney disease is associated with poor prognosis. We assessed the effect of renal function on exercise capacity and clinical parameters of patients with HF. Material and methods orty five patients aged 58.2 ± 10.6 years with stable severe HFrEF were recruited. Patients were divided into 3 groups: group 1 - eGFR: 30-59 ml/min/1.73 m2; group 2 - eGFR: 60-89 ml/min/1.73 m2 and group 3 - eGFR: ≥90 ml/min/1.73 m2. Biochemical analysis, echocardiography, 6-minute walking test and cardiopulmonary stress testing were performed. Results Patients in group 1 were significantly older than patients in group 3 (60.4 ± 11.1 years vs. 49.25 ± 11.2 years, respectively, p<0.05). Patients in group 2 had significantly higher BMI in comparison to group 3 (29.8 ± 4.4 vs. 25.1 ± 4.2; p<0.05). Interestingly, patients in group 1 had significantly lower peak oxygen uptake (10.2 ± 3.1 ml/kg/min vs. 16.1 ± 3.5 ml/kg/min, p<0.05) and oxygen uptake at anaerobic treshold (7.9 ± 2.4 ml/kg/min vs. 10.7 ± 1.9 ml/kg/min, p<0.05). Conclusions Diminished renal function in patients with stable, advanced HFrEF may be associated with significantly worse peak VO2 and VO2 in AT.

3

Obesity: reversible biological adaptation or disease?

88%

Pilis K. , Pilis A. , Stec K. , Michalski C. , Zych M. , Buchta J. , Pilis W.

Physical Activity Review

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2016

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tom 4

18-27

EN

Introduction: Obesity is an unfavorable state of health as a result of which come in the initial adaptation, that could gradually transform into specific disease condition. Objectives: The aim of the study was to assess the degree of middle-aged men adaptation to obesity in terms of somatic changes, exercise capacity and cardiopulmonary fitness. Materials and Methods: The study involved 12 obese middle-aged men (OG) - BMI = 34.32 ± 4.11 kg/m2. The control group (CG) consisted of 12 non-obese middle-aged men- BMI = 23.72 ± 1.83 kg/m2,with similar body height (BH) to OG. After recording somatic and physiological data at rest, participants were subjected to the bicycle ergometer test (BT) gradually increasing intensity. During the BT aerobic power (AP) was recorded and analyzed along with parameters characterizing the efficiency of the circulatory and respiratory systems at anaerobic threshold (AT) and the maximum load (ML). Results: This study has shown that obese men have a higher body mass (BM), a higher content of fat (BF), an increased lean body mass (FFM) and a higher content of water (TBW) than CG (p <0.001). Absolute and relatively expressed in relation to the FFM respondents’ values of AP and VO2 were similar in both groups and after taking under the consideration the body weight, they were significantly lower in OG than in the CG. Furthermore, adverse effects have been observed that emerged on some cardiovascular and respiratory variables at rest in case of OG; these effects did not occur during physical exertion. Conclusions: Beyond negative changes occurring obesity in the first stage led to favorable somatic adaptation that entails an increase of FFM in OG, which gives a positive impact on the capacity of physical work of obese men and produces a beneficial effect on the resulting compensation impairment in the respiratory and circulatory systems of these subjects.

4

Cardiovascular response to exercise in hypertension – clinical characteristics of ASSECURE study participants

88%

Kurpaska M. , Krzesiński P. , Gielerak G. , Uziębło-Życzkowska B. , Banak M. , Maciorowska M. , Skrobowski A. , Stańczyk A. , Piotrowicz K.

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2019

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tom 15

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nr 1

47-56

EN

Aim: Arterial hypertension leads to progressive cardiovascular dysfunction and heart failure. The aim of the study was to assess exercise capacity in hypertensives with the use of a cardiopulmonary exercise test, impedance cardiography and 6-minute walk test with special emphasis on haemodynamic response to exercise workload. Methods: 114 patients (53.5% women, 55.7 ± 9.1 years) were evaluated for reported symptoms, N-terminal pro-B-type natriuretic peptide (NTproBNP) levels, echocardiographic parameters and exercise capacity with 6-minute walk test, cardiopulmonary exercise test and haemodynamic parameters (by means of impedance cardiography). Results: 50% of patients had reported symptoms of impaired exercise tolerance, mostly dyspnoea on exertion (37.7%). NTproBNP levels exceeded 125 pg/mL in 19.3% of patients. Left ventricular diastolic dysfunction was found in 8.8% and heart failure was diagnosed in 6.2% of patients. A wide range of peak oxygen uptake (peak VO2) and 6-minute walk test distance was observed: 19.4 ± 5.2 mL/min/kg and 526.7 ± 112.0 m, respectively. A major proportion of patients demonstrated decreased exercise capacity parameters: 56.1% achieving peak VO2 < 22 mL/min/m2; 45.9% achieving peak VO2 < 80% of the predictive value; 37.3% achieving 6-minute walk test distance shorter than the predicted values. The impedance cardiography recorded at peak exercise: heart rate 147.2 ± 22.4 bpm, stroke volume 110.2 ± 21.8 mL, cardiac output 15.9 ± 4.2 L/min, peak systemic vascular resistance 587.4 ± 168.0 dyn.s/cm5. Conclusions: Although a very small proportion of patients with uncomplicated arterial hypertension meet the criteria for being diagnosed with heart failure, the symptoms of impaired exercise tolerance as well as abnormal results of objective exercise capacity assessments are quite common in these patients.

PL

Cel: Nadciśnienie tętnicze prowadzi do postępującej dysfunkcji układu krążenia i niewydolności serca. Celem pracy była ocena wydolności fizycznej chorych z nadciśnieniem tętniczym z wykorzystaniem sercowo-płucnego testu wysiłkowego, wysiłkowej kardiografii impedancyjnej oraz 6-minutowego testu marszowego, ze szczególnym uwzględnieniem odpowiedzi hemodynamicznej na obciążenie wysiłkiem. Metody: 114 chorych (53,5% kobiet, wiek 55,7 ± 9,1 roku) oceniono pod względem zgłaszanych objawów, stężenia N-końcowego propeptydu natriuretycznego typu B (N-terminal pro-B-type natriuretic peptide, NTproBNP), wykładników echokardiograficznych oraz wydolności fizycznej za pomocą 6-minutowego testu marszowego i sercowo-płucnego testu wysiłkowego, a także parametrów hemodynamicznych za pomocą wysiłkowej kardiografii impedancyjnej. Wyniki: W badanej grupie 50% osób zgłaszało obniżenie tolerancji wysiłku, w tym 37,7% duszność wysiłkową. U 19,3% chorych stężenie NTproBNP przekroczyło wartość 125 pg/ml. Dysfunkcję rozkurczową stwierdzono u 8,8% z nich, ale kryteria rozpoznania niewydolności serca z zachowaną frakcją wyrzutową spełniło jedynie 6,2%. Obserwowano szeroki zakres szczytowego pochłaniania tlenu (peak VO2) i dystansu 6-minutowego testu marszowego, odpowiednio 19,4 ± 5,2 ml/min/kg i 526,7 ± 112,0 m. Wysoki odsetek badanych prezentował obniżone parametry wydolności fizycznej: 56,1% osiągnęło peak VO2 < 22 ml/min/m2, a 45,9% – peak VO2 < 80% wartości predykcyjnej; 37,3% badanych nie osiągnęło należnej wartości dystansu 6-minutowego testu marszowego. W wysiłkowej kardiografii impedancyjnej zarejestrowano na szczycie wysiłku: częstość rytmu serca 147,2 ± 22,4/min, objętość wyrzutową 110,2 ± 21,8 ml, pojemność minutową 15,9 ± 4,2 l/min, opór obwodowy 587,4 ± 168,0 dyn.s/cm5. Wnioski: Objawy obniżonej tolerancji wysiłku i nieprawidłowe wyniki obiektywnej oceny wydolności fizycznej u pacjentów z niepowikłanym nadciśnieniem tętniczym są częste, chociaż niewielki odsetek tych chorych spełnia kryteria diagnostyczne niewydolności serca.

5

The influence of extending early stationary rehabilitation by ambulatory form in patients treated interventionally after ACS on the exercise capacity on the components of psychic state of mind and quality of life

63%

Przywarska I. , Deskur-Smielecka E. , Borowicz-Bienkowska S. , Wilk M. , Brychcy A. , Dylewicz P.

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tom 13(2)

12-16

EN

Objectives: The evaluation of the direct and remote effects of stationary rehabilitation following interventionally treated acute coronary syndrome and its extension by a three-month period of supervised training in ambulatory conditions within the scope of physical capacity psychic state and quality of life.Materials and methods: The research was conducted in a group of 44 patients (32 men and 12 women) aged 56.9±9, 62 years old for a period of 2-3 weeks following interventional treatment of acute coronary syndrome. All the patients had participated in stationary rehabilitation, 14 of whom expressed a willingness to participate in a futher three-month period of ambulatory rehabilitation. All patients prior to the commencement of rehabilitation had threadmill exertion tests. Fear was evaluated by means of the SOPER questionnaire. Basic mood and psychic tension as well as the feeling of health were assessed by means of the VAS scale of the Euro-Qol 5D questionnaire. The set of tests was repeated after the completion of the stationary phase, and after time periods of 3 months and a year.Results: Patients subjected to the extended 3-month ambulatory phase of rehabilitation displayed a greater increase in exercise tolerance when compared with the group that had merely undergone the 3-week stationary rehabilitation. Patients with extended rehabilitation gradually improved their evaluation of their state of health and after a year maintained it at the level it had been after the completion of the stationary rehabilitation. In patients who did not express a willingness to continue an organised form of exercise in ambulatory conditions the noticeable improvement in health following the end of rehabilitation was not long lasting. After a year, regardless of the programme of rehabilitation selected, an improvement in the psychic state was noted, which was expressed in an increased positive mood although the level of fear did not change to a significant degree.Conclusions: 1. Extended rehabilitation, combining stationary and ambulatory forms, after interventional treatment of ACS gives a better long-term effect in the area of improving exercise capacity and patient self-evaluation of state of health than is in the case after three-week stationary rehabilitation. 2. The extending of the period of rehabilitation has no influence on attaining the postrehabilitation changes on the level of mood and fear.

6

Effects of continuous positive airway pressure on exercise capacity in chronic heart failure patients without sleep apnea

51%

Steiner S. , Schueller P. O. , Schannwell C. M. , Hennersdorf M. , Strauer B. E.

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2007

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tom 58

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nr 5

7

Self-reported physical activity versus physical function capacity: alternatives for energy expenditure estimation

51%

Mbada C. E. , Osifeso T. A. , Johnson O. E. , Okonji A. M. , Odeyemi E. A.

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2016

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tom 20(4)

4-12

PL

Wstęp: Stopień, w jakim deklarowana aktywność fizyczna oceniania za pomocą Międzynarodowego Kwestionariusza Aktywności Fizycznej (IPAQ) może zastąpić opartą o wyniki wydolność funkcjonalną mierzoną testem 6-minutowego chodu (6MWT) pozostaje niejednoznaczny. W badaniu tym oceniano aktywność fizyczną (AF) i funkcjonalną wydolność wysiłkową (FEC); a także określono zależność pomiędzy PA i FEC u pozornie zdrowych, młodych dorosłych. Materiał i metody: Badaniem objęto 342 studentów (145 mężczyzn i 197 kobiet) z Obafemi Awolowo University, Ile-Ile, Nigeria. IPAQ został wykorzystany do oceny AF, podczas gdy FEC oceniano za pomocą 6MWT i wyrażono w sześciominutowym dystansie chodu (6MWD), pracy wykonanej podczas sześciominutowego chodu (6MWW), maksymalnym minutowym poborze tlenu (VO2max) i równoważniku metabolicznym (MET). Parametry antropometryczne i układu krążenia były mierzone zgodnie ze standardowymi procedurami. Dane analizowano przy użyciu wnioskowania statystycznego i opisowego. Poziom alfa został ustalony na poziomie 0,05. Wyniki: Średni wiek uczestników wyniósł 22,0 ±2,87 lat. Średni wynik IPAQ wszystkich uczestników to 1471,4 ±1086,93. Procent dla niskiego, średniego i wysokiego poziomu AF to odpowiednio 19% (65), 41,2% (141) i 39,8% (136). Średni 6MWD, 6MWW, VO2max i METS wyniosły odpowiednio 639.47 ±66,6 m, 41805.0±8520,6 kg·m, 28,9±1,92 mlO2k-1min-1, 4,05±0,32 ml/kg. Istnieją znaczące dodatnie korelacje pomiędzy PA i każdym z 6MWD (r=0,268, p=0,001), 6MWW (r=0,219, p=0,001), VO2max (r=0,268, p=0,001), METS (r=0,268; p=0,001). Miary wydolności wysiłkowej nie były istotnie skorelowane ze zmiennymi antropometrycznymi (p>0,05). Wnioski: Deklarowany poziom aktywności fizycznej u zdrowych młodych dorosłych nie jest adekwatny do wyników testu sześciominutowego marszu.

EN

The extent to which self-report activity measured by the International Physical Activity Questionnaire (IPAQ) can substitute performance-based functional capacity measured by the Six-Minute Walk Test (6MWT) remains inconclusive. This study assessed Physical Activity (PA) and Functional Exercise Capacity (FEC); and also determined the relationship between PA and FEC in apparently healthy young adults. A total of 342 (145 males and 197 females) undergraduates of Obafemi Awolowo University, Ile-Ile, Nigeria participated in the study. The IPAQ was used to assess PA, while FEC was assessed using the 6MWT, and expressed in terms of the Six-Minute Walk Distance (6MWD), Six-Minute Walk Work (6MWW), Maximum Oxygen Uptake (VO2max) and Metabolic Equivalent (METS). Anthropometric and cardiovascular parameters were measured following standardized procedures. Data was analyzed using descriptive and inferential statistics. The alpha level was set at 0.05. The mean age of the participants was 22.0±2.87 years. The mean IPAQ score of all participants was 1471.4±1086.93. The percentage for low, moderate and high PA was 19% (65), 41.2% (141) and 39.8% (136), respectively. The mean 6MWD, 6MWW, VO2max and METS were 639.47 ±66.6 m, 41805.0 ±8520.6 kg·m, 28.9 ±1.92 mlO2k-1min-1, 4.05 ±0.32 mL/kg, respectively. There were signifi cant positive correlations between PA and each of the 6MWD (r=0.268; p=0.001), 6MWW (r=0.219; p=0.001), VO2max (r=0.268; p=0.001), METS (r=0.268; p=0.001). Measures of exercise capacity were not signifi cantly correlated with the anthropometric variables (p>0.05). Self-report of physical activity in healthy young adults does not adequately substitute the results of the Six-Minute Walk Test. Mbada Ch.E., Osifeso T.A., Johnson O.E., Okonji A.M., Odeyemi E.A. Self-reported physical activity versus physical function capacity: alternatives for energy expenditure estimation. Med Rehabil 2016; 20(4): 4-12. DOI: 10.5604/01.3001.0009.5479 null