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1 Journal of Achievements in Materials and Manufacturing Engineering

1 2009

1 Mitura K.

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HR TEM examinations of nanodiamond particles for biomedical application

100%

Mitura K.

2009

tom Vol. 37, nr 2

317-322

Purpose: The aim of the study is an analysis of a different type of nano-diamond powders on HR TEM (material characterisation, the normal distribution of grain size). These nano-powders were used in many biological researches and each of them had a special biological activity. Comparison between the material and biological properties of diamond powders answered many questions about the chemical and physical reactions on a boundary: diamond surface – living organism. Design/methodology/approach: In this work we used cytotoxicity assays using MTT test and HR TEM examinations. We examined the nanodiamond particles manufactured by detonation method, RF/MW PACVD method, RF PACVD method, pure diamond from De Beers Company and graphite powder as a control. Findings: In this subject the material characterisation of diamond powders are known but we examined a different type of powders and we manufactured some of these nanopowders in our laboratory. Practical implications: Nanocrystalline Diamond Coatings have many applications in various fields of medicine. Nanodiamond Particles are an extended surface of diamond powder. Biological research with endothelial and lung cancer cells are the introduction to application in human’s treatment. Originality/value: There are in vitro examinations with bioactive biomaterial. Nanodiamond particles have a very high bioactivity on cell level and inhibit cancerogenesis.