Wyniki wyszukiwania - Biblioteka Nauki

1

Critical swim speed and metabolic activities in trained male and female swimmers after 400 m free style swimming with their full effort

100%

Chatterjee P. , Nandy P. , Chakraborty S. , Bandyopadhyay A.

Progress in Health Sciences

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2016

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tom 6(2)

46-50

EN

Purpose: This study was done to ascertain gender dif ferences in trained swimmers between their Critical S wim Speed (CSS). Certain metabolic responses, imme diately after 400 meters free style swimming (FSS), w ith maximum effort, were also studied. Methods: The analysis was conducted in trained swi mmers between 12- 18 years age. Height, weight, bod y fat quantity were estimated using standard techniqu es. CSS was measured for each swimmer. Blood samp les were taken within two minutes of 400 meters FSS, with maximum efforts. The blood creatinine, lactic ac id, serum calcium, serum urea and serum urea nitroge n were estimated using standard laboratory methods. Results: With the maximal effort of 400 meters FSS, values of hematological variables for both sexes were found to increase many folds than reference values. Si gnificant (p<0.05) gender differences were observed in CSS and blood creatinine. The positive significant (p<0.05) correlation was found between CSS and heig ht in the swimmers. For trained male swimmers signif icant positive correlations among CSS, blood urea an d serum urea nitrogen were found. Conclusions: This study reflects metabolic status of b oth trained male and female swimmers, after their full efforts. Besides blood creatinine no significant differe nces were observed in them. So it may conclude that e ffective physical training minimizes the metabolic de mands during their full efforts and gender differences could be overcome.

2

Assessment of serum creatinine, urea, and aminotransferase levels among methamphetamine addicted individuals in Khartoum State

100%

Al-Tayeb A.-N. O. , Abubakr M. H. , Elrheima H. A. , Habbani A. K. , Elrasul R. Y. H.

European Journal of Clinical and Experimental Medicine

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2024

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tom 22

|

nr 1

68-72

EN

Introduction and aim. Methamphetamine-use disorder is a pressing global public health issue. In Sudan, the escalating methamphetamine (METH) consumption has become a significant social and health problem. This study aims to evaluate liver and kidney biomarkers in methamphetamine addicts in Khartoum state. Material and methods. The study was an analytical prospective cross-sectional hospital-based study. One hundred participants were enrolled in this study, fifty were cases (methamphetamine addicts), and others were healthy non-METH users as a comparative group. Results. METH users had a mean age of (27±7) years and had been using METH for an average of (14±9) months. Urea and creatinine levels were also significantly elevated in METH users compared to non-users, with p<0.001 and p=0.044, respectively. Their aspartate transaminase (AST) and alanine transaminase (ALT) levels were significantly higher compared to non-users, with p<0.001. Conclusion. There was significant increases in creatinine, urea, and aminotransferases levels in the case group. ALT showed a moderate positive correlation with abuse duration, while AST showed no significant correlation. Urea and creatinine levels had strong and moderate positive correlations with abuse duration, respectively.

3

Decreases in urine specific gravity and urinary creatinine in dogs with different diseases but with normal renal function

75%

Fojut-Palka B. , Winnicka A.

Polish Journal of Veterinary Sciences

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2008

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tom 11

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nr 1

41-46

EN

The subject of this study was to determine urine specific gravity (USg) and urinary creatinine (UCrn) in dogs with different diseases but with normal renal function. Sick dogs with different diseases were divided into nine groups. Dogs suffering from polyuria/polydipsia, vomits, diarrhoea and females in oestrus or pregnant were excluded from the studies. The healthy dogs served as a control group. Over a three-year period, a total of 267 dogs were examined clinically as well as using imaging and laboratory diagnostics methods. In sick dogs, USg and UCrn were found to be essentially decreased (except animals with neurological and uterine diseases, and neurological diseases, respectively), as compared with normal dogs. In clinically healthy animals of the control group, UCrn and USg did not significantly differ between the females and males. As for the control group, no correlation between UCrn/USg and the body weight/age was found, either.

4

Creatinine and Creatininium Cation in Water Solution. Tautomerism and Quantitative Interpretation of the Solution Acidity Effect on 1H, 13C and 14 N NMR Chemical Shifts

75%

Kotsyubynskyy D. , Molchanov S. , Gryff-Keller A.

Polish Journal of Chemistry

|

2004

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tom Vol. 78 / nr 2

239-248

EN

1H, 13C and 14N NMR chemical shifts for creatinine in water solutions of various acidity have been measured. Analysis of these data enabled determination of the acidity constant of creatininium cation and the chemical shifts of the neutral and protonated forms of creatinine. Molecular energies and carbon and nitrogen magnetic shielding constants for various tautomeric structures of the investigated species have been calculated using the quantum chemistry method GIAO DFT B3LYP/6-311++G(2d,p). Compilation of the available experimental and theoretical results has provided additional information on the problem of tautomerism of this important biological molecule.

5

Post-exercise proteinuria in the cadets trained on Special Aerial Gymnastics Instruments

75%

Wochyński Z. , Sobiech K.

International Journal of Occupational Medicine and Environmental Health

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2015

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tom 28

|

nr 5

863-873

EN

Objectives Assessment of the effect of training on Special Aerial Gymnastics Instruments (SAGI) on the urine β-2- microglobulin (β-2M), albumin (ALB), total protein (TP), N-acetyl-β-D-glucosaminidase EC.3.2.1.30 (NAG), expressed as creatinine (Cr) and on the physical fitness of the examined cadets in comparison with the control group. Material and Methods The study involved 55 cadets aged 20, divided into group A (N = 41) trained on SAGI, and group B (N = 14) – a control group. The urine was collected twice: before the training (BT) and after the training (AT) at the start (training I), during (training II), and after completion of the training program (training III). Urine proteins were assayed with commercially available kits. Results In group A, results obtained in trainings I, II and III showed a statistically significant increase in β-2M/Cr, NAG/Cr, TP/Cr, ALB/Cr indices in AT compared with the baseline BT values. Similarly in group B, a statistically significant increase in β-2M/Cr, NAG/Cr (trainings I, II), TP/Cr, AT compared with the baseline BT values in trainings I, II, and III was noted. Comparison of both groups showed a higher value of the post-exercise proteinuria in group B than in group A. In group A, a significant correlation between TP/Cr vs. ALB/Cr, NAG/Cr vs. TP/Cr, β-2M/Cr vs. TP/Cr, i.e., r = 0.62 at p < 0.001; r = 0.33 at p = 0.03; r = 0.60 at p < 0.001, and r = 0.52 at p < 0.001, respectively, was observed in group A, training III, AT. Conclusions Assayed urine proteins depend on the intensity of physical exercise, the type of exercise, and the level of physical fitness.

6

Capacitive sensors based on a photografted molecularly imprinted polymers

75%

Panasyuk-Delaney T. , Mirsky V. M. , Wolfbeis O. S.

Biocybernetics and Biomedical Engineering

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2001

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tom Vol. 21, no. 3

43-54

EN

The reversible chemosensors to creatinine and desmetryn based on artificial chemoreceptors are described. A grafted photopolymerization combined with a technique of molecular imprinting was used for the receptor layer preparation. After polymer deposition and intensive washing from templates, the electrodes were investigated by impedance spectrometry. Creatinine and desmetryn binding were detected as a decrease in the electrode capacitance. Sensor response to creatining was highly selective. No response to the addition of sodium chloride, creatine, urea or glucose were observed. The electrodes coated with the molecularly imprinted polymers selective to desmetryn displayed specific binding of this herbicide: only small capacitive effects were observed to addition of terbumeton or atrazine, while metribuzine displayed capacitance decrease similar to desmetryn.

PL

W artykule opisano odwracalne czujniki chemiczne kreatyniny i desmetryny oparte na sztucznych chemoreceptorach. W celu wykonania warstwy receptorowej użyto szczepionej fotopolimeryzacji w połączeniu z techniką znakowania molekularnego. Po nałożeniu polimeru i obmyciu substancją wzornikową, elektrody były badane metodą spektroskopii impedancyjnej. Wiązanie kreatyniny i desmetryny objawiało się w postaci zmniejszenia pojemności elektrody. Odpowiedź czujnika na kreatyninę była bardzo selektywna. Nie obserwowano odpowiedzi na dodanie chlorku sodu, kreatyny, mocznika lub glukozy. Elektrody pokryte polimerami znakowanymi molekularnie, selektywne na desmetryn wykazywały specyficzne wiązanie tego herbicydu: obserwowano tylko małe zmiany pojemności po dodaniu terbumetonu lub atrazyny, natomiast metrabuzyna wykazywała zmiany pojemności podobne do desmetrynu.

7

The influence of icodextrin on creatinine and albumin transport acros the peritoneal membrane in vitro

75%

Grzelak T. , Czyzewska K. , Szary B.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr Suppl.

8

Assessment of hepatorenal functions in pesticide applicators in some Egyptian governorates

75%

Amr M. M. , El-Medany T. M.

Annals of Agricultural and Environmental Medicine

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1994

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tom 01

|

nr 2

9

Molar ratio of uric acid versus creatinine in human urine is higher in women than in men and is lowered by physical activity

75%

Matuszkiewicz A.

Polish Journal of Environmental Studies

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1999

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tom 08

|

nr 5

10

Lead-elevated activity of xanthine oxidase in lead-exposed workers

63%

Kasperczyk S. , Dobrakowski M. , Ostałowska A. , Kasperczyk A. , Wilczyński S. , Wyparło-Wszelaki M. , Kiełtucki J. , Birkner E.

Medycyna Pracy

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2013

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tom 64

|

nr 2

175-180

PL

Wstęp: Celem pracy była analiza wpływu narażenia na ołów na aktywność oksydazy ksantynowej (xanthine oxidase - XO). Dodatkowo wyznaczono stężenia kwasu moczowego (uric acid - UA) i kreatyniny. Natężenie stresu oksydacyjnego oszacowano na podstawie stężenia dialdehydu malonowego (malondialdehyde - MDA). Materiał i metody: Grupę badaną stanowiło 125 zdrowych pracowników huty cynku i ołowiu. Stopień narażenia na ołów oceniano na podstawie stężenia ołowiu i cynkoprotoporfiryny we krwi, a także kwasu delta-aminolewulinowego w moczu. Na podstawie stężenia ołowiu we krwi grupa badana została podzielona na tercyle. W próbkach krwi uzyskanych od uczestników badania dokonano analizy wyżej wymienionych parametrów biochemicznych. Grupę kontrolną stanowiło 32 zdrowych pracowników administracji nienarażonych na ołów. Wyniki: Aktywność XO i stężenie MDA były znamiennie wyższe we wszystkich tercylach w porównaniu z grupą kontrolną. Stężenie kreatyniny osiągnęło także znamiennie wyższe wartości, lecz tylko w środkowym i górnym tercylu. Z kolei stężenie UA było znamiennie wyższe wyłącznie w górnym tercylu. Jednocześnie zaobserwowano tendencję do wyższych wartości jego stężenia w dwóch pozostałych tercylach. Wnioski: Zawodowe narażenie na ołów indukuje wzrost aktywności XO, który może przyczyniać się do nasilenia stresu oksydacyjnego, mierzonego jako stężenie MDA, i powodować wzrost stężenia UA. Med. Pr. 2013;64(2):175–180

EN

Background: The aim of the present study was to explore the connection between lead toxicity and the activity of xanthine oxidase (XO). In addition, we indicated the uric acid (UA) and creatinine levels and concentration of erythrocyte malondialdehyde (MDA) to estimate oxidative stress intensity. Materials and Methods: The examined group consisted of 125 healthy male employees of zinc and lead works. The examined group was divided into tertiles according to blood lead levels. In the collected blood samples, concentrations of lead-exposure indices, UA, creatinine, and MDA as well as activity of XO were measured concomitantly. The control group consisted of 32 healthy male administrative workers who were exposed to lead only environmentally. Results: XO activity and MDA level were significantly elevated in all tertiles compared to the control group. Creatinine level was significantly elevated in the medium and high tertiles. However, the level of UA was significantly elevated in the high tertile, while in the low and medium tertile only a tendency toward higher values was observed. Conclusions: Occupational exposure to lead induces activity of XO. This induction may contribute to the observed simultaneously increased oxidative stress, measured as MDA level, and the increased level of UA. Med Pr 2013;64(2):175–180

11

The urine podocin/creatinine ratio as a novel biomarker of cardiorenal syndrome in dogs due to degenerative mitral valve disease

63%

Szczepankiewicz B. , Paslawska U. , Paslawski R. , Gebarowski T. , Zasada W. , Michalek M. , Noszczyk-Nowak A.

Journal of Physiology and Pharmacology

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2019

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tom 70

|

nr 2

12

Different Complexation Behavior of a Proton Transfer Compound Obtained from Pyridine-2,6-dicarboxylic Acid and Creatinine with Tl(I), Cu(II), Fe(III) and Bi(III): Synthesis, Characterization, Crystal Structures and Solution Studies

63%

Aghabozorg H. , Ramezanipour F. , Soleimannejad J. , Sharif M. A. , Shokrollahi A. , Shamsipur M. , Moghimi A. , Attar Gharamaleki J. , Lippolis V. , Blake A. J.

Polish Journal of Chemistry

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2008

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tom Vol. 82, nr 3

487-507

EN

The different complexation methods of a proton transfer compound, (creatH)(pydcH)źH2O (pydcH2 = pyridine-2,6-di carboxylic acid; creat = creatinine) with metal ions have been studied and formation of [(Tl(pydcH)]n (1), [(Fe(pydc)(H2O)2)2ox]ź6H2O (2), [Cu(pydc)(pydcH2)]ź2H2O (3) and (creatH)2[Bi(pydc)2]2ź4H2O (4) are re ported. The characterization was performed using IR spectroscopy and single crystal X-ray diffraction analysis. The Tl(I) complex [(Tl(pydcH)]n (1) obtained from (creatH)(pydcH)źH2O is a polymeric system, showing only the contribution of the anionic species of (creatH)(pydcH)źH2O to the complexation. The Fe(III) and the Cu(II) complexes [(Fe(pydc)(H2O)2)2ox]ź6H2O (2) (ox = ox a late) and [Cu(pydc)(pydcH2)]ź2H2O (3) were also obtained from (creatH)(pydcH)źH2O. The Bi(III) complex (creatH)2[Bi(pydc)2]2ź4H2O (4) is a dimeric system, showing both contribution of the cationic and anionic fragments. The complexes 1-4 show a variety of structural features including mononuclear, binuclear, polymeric structures and unusual ligand formation. In compounds (1), (2), (3) and (4), a large number of hydrogen bonds are observed. These interactions as well as p-p stacking play an important role in the formation and stabilization of supra molecular systems in the crystal lattices. The stoichiometry and stability of the Cu(II), Tl(I) and Bi(III) complexes with (pydc)(creat) and Fe(III) with pydc-ox mixture in aqueous solution were investigated by potentiometric pH titration.

13

The protective effects of zinc in experimental gentamicin induced acute renal failure in rats

63%

Teslariu O. , Pasca A. S. , Mititelu-Tartau L. , Schiriac C. E. , Gales C. , Saftencu P. M. , Nechifor M.

Journal of Physiology and Pharmacology

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2016

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tom 67

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nr 5

14

Ślady krwi na Całunie Turyńskim : analiza materiałowa od mikro do nanoskali

63%

Jaworski J. S.

Wiadomości Chemiczne

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2018

|

tom [Z] 72, 1-2

61--80

EN

Modern experimental methods of materials science including optical and electron microscopy (SEM, ESEM, HRTEM), X-ray spectroscopy (EDX, WAXS), Raman and FTIR spectroscopy used in investigations of structures of new materials can be also successfully applied for analysis of archeological, cultural heritage and art objects. An interesting example of such analyses are investigations of microscopic fibers and particles taken previously from areas attributed to the blood on the Shroud of Turin. Detailed analyses performed by a number of research groups published in 2015–2017 are reviewed. They confirmed previous hypothesis on blood authenticity and discovered new evidences indicated a violence hidden behind the death. In particular, the presence of old red blood cells was documented by Lucotte [20], of bile pigment biliverdin by Laude and Fanti [28], of iron oxide cores of ferritin bounded to nanoparticles of creatinine by Carlino et al. [31]. The last result is typical for patients with severe polytrauma indicating at the unexpected nonoscopic level a tremendous suffering of the victim wrapped in the Shroud of Turin. Bigger particles of mineral pigments: ochre (iron oxide) and vermillion (mercury sulfide) were also found but they can be easily distinguished form blood particles using environmental electron microscopy ESEM with the back-scattered electrons detector [24]. The statistical analysis of a sample composition made by Fanti and Zagotto [24] indicated that 90–95% of the observed volume corresponds to the blood and only remainder represents inorganic pigments. Thus, it was proposed [24] that the original human blood on Shroud stains was much later reinforced by red pigments using a color dust without any binder and this hypothesis can easily explain controversies between previous results of different researches.

15

Systemic and local effects of intragastric administration of the habanero fruit (Capsicum chinense jacquin c.v.) in rats

63%

Golynski M. , Balicki I. , Lutnicki K. , Smiech A. , Adamek L. , Szczepanik M. , Wilkolek P. , Brodzki A. , Adaszek L.

Journal of Physiology and Pharmacology

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2015

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tom 66

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nr 2

16

Plasma cystatin C concentration in non-insulin-dependent diabetes mellitus: relation with nephropathy

63%

Piwowar A. , Knapik-Kordecka M. , Buczynska H. , Warwas M.

Archivum Immunologiae et Therapiae Experimentalis

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1999

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tom 47

|

nr 5

17

Changes in selected blood serum indices before and after parturition in mares

51%

Ozpinar A. , Susut M. D. , Firat A.

Medycyna Weterynaryjna

|

2004

|

tom 60

|

nr 12

1283-1286

18

Nefropatia kontrastowa

51%

Lichosik M. , Jung A. , Spałek M. , Chorążka K.

Pediatria i Medycyna Rodzinna

|

2012

|

tom 8

|

nr 4

324-328

EN

Recent clinical data suggest that contrast‑induced nephropathy (CIN), defined as a rapid deterioration of renal function that usually occurs 48‑72 hours after the administration of the contrast agent, is much more common than previously thought. In most cases, the clinical course of acute renal failure is mild and transient, but it has been proved that even a subtle impairment of renal function causes severe clinical consequences in the future. The difficulties in diagnosis of CIN is further aggravated by the fact that the kidney damage caused by contrast agent administration usually takes place without obvious clinical symptoms and oliguria. Current researches focus on improving the diagnostic process and try to develop effective prophylactic protocols. The increase in serum creatinine concentration is relatively late indicator of acute kidney injury thus more useful markers are being investigated. High expectations are given by clinical use of cystatin C, NGAL and interleukin 18. Many publications are focused on attempts of identifying risk factors of contrast‑induced nephropathy. It is already known that a very careful intravascular contrast administration is needed in case of patients with chronic renal disease or diabetes mellitus. Procedure dependable risk factors are as following: a type and dose of contrast agent, a method of contrast administration or repeatability of the procedure in a short period of time. The highest prophylactic value has an adequate hydration of the patient, moreover, N‑acetylcysteine has been found as the most promising pharmacological agent.

PL

Aktualne dane kliniczne wskazują, że nefropatia kontrastowa (contrast-induced nephropathy, CIN), definiowana jako nagłe – w ciągu 48‑72 godzin – pogorszenie funkcji nerek po podaniu kontrastu, występuje o wiele częściej, niż dotychczas sądzono. W większości przypadków przebieg nefropatii kontrastowej jest łagodny i przemijający, niemniej udowodniono, że nawet niewielkie upośledzenie funkcji nerek powoduje odległe następstwa kliniczne. Rozpoznanie dodatkowo utrudnia fakt, że uszkodzenie nerek spowodowane podaniem kontrastu zazwyczaj przebiega bez wyraźnych objawów klinicznych i skąpomoczu. Aktualnie naukowcy koncentrują się na doskonaleniu postępowania diagnostycznego oraz próbach opracowania skutecznych protokołów postępowania profilaktycznego. Ponieważ kryterium wzrostu stężenia kreatyniny jest stosunkowo późnym wskaźnikiem ostrego uszkodzenia nerek, poszukuje się bardziej użytecznych markerów. Do budzących duże nadzieje na wykorzystanie kliniczne należą cystatyna C, NGAL i interleukina 18. Wiele publikacji skupionych jest na próbach identyfikacji czynników ryzyka dla wystąpienia nefropatii kontrastowej. Wiadomo już, że szczególną ostrożność, przy donaczyniowym podawaniu kontrastu, należy zachować w przypadku pacjentów z przewlekłą chorobą nerek czy cukrzycą. Do czynników ryzyka zależnych od procedury zaliczamy rodzaj i dawkę środka kontrastowego, sposób podania substancji kontrastowej oraz powtarzalność zabiegu w krótkich odstępach czasu. W postępowaniu profilaktycznym największą wartość ma adekwatne nawodnienie chorego, a wśród testowanych środków farmakologicznych największe nadzieje w chwili obecnej budzi N‑acetylocysteina.

19

Effects of alfacalcidol on the contractile properties of the gastrocnemius medialis muscle in adult and old rats

51%

Testerink J. , Degens H. , Rittweger J. , Shiraishi A. , Jaspers R. T. , De Haan A.

Journal of Physiology and Pharmacology

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2011

|

tom 62

|

nr 1

EN

Vitamin D deficiency is associated with muscle weakness. It is unknown, however, how supra-physiological levels of vitamin D affect skeletal muscle. To investigate the effects of increased serum vitamin D (1,25 (OH)2D3 or 1,25D) levels on the contractile properties of the medial gastrocnemius muscle, adult and old female Fischer344 x Brown Norway F1 rats were orally treated with vehicle or the vitamin D analogue alfacalcidol for 1 or 6 weeks. Alfacalcidol treatment resulted in elevated 1,25D serum levels. This was accompanied by hypercalcaemia and a reduction in body mass, the latter largely attributable to a reduced food intake. However, kidney function, as reflected by normal creatinine serum levels, as well as heart mass were unaffected. The 17% reduction in maximal isometric force and power was explicable by a similar loss of muscle mass. The force-frequency relationship of the 6-week-treated old rats was shifted to the left, but neither the shape of the force-velocity relationship nor the fatigability of the muscle were altered. Supra-physiological doses of vitamin D were accompanied by significant reductions in body and muscle mass, but not by an improvement in muscle functioning. Weight loss was largely due to a reduced food intake, while the left shift in the force-frequency relation may be due to increased 1,25D levels.

20

Increased serum urea to creatinine ratio and its negative correlation with arterial pressure in canine babesiosis

51%

Zygner W. , Gojska-Zygner O.

Acta Parasitologica

|

2014

|

tom 59

|

nr 3

EN

The increase of the serum urea to creatinine ratio (UCR) was observed in dogs infected with Babesia canis. Previous studies have suggested that decrease of blood pressure can be one of the reasons for this phenomenon. In this work statistically significant increase of the UCR was observed in dogs with babesiosis. Comparison of the UCR between 23 azotaemic dogs and 25 non-azotaemic dogs infected with Babesia canis showed statistically significantly higher mean of the UCR in azotaemic dogs. Correlations between UCR and systolic, diastolic and mean arterial pressure (SAP, DAP and MAP) in 48 dogs infected with B. canis were negative (UCR and SAP: r = −0.3909; UCR and DAP: r = −0.3182; UCR and MAP: r = −0.3682) and statistically significant (p < 0.05). This result may indicate contribution of hypotension in the increase of the UCR in canine babesiosis. However, the correlations were not high, and there was no statistically significant correlation between UCR and arterial pressures in azotaemic dogs. Thus, it seems that decrease of blood pressure in dogs with babesiosis explains only partially the cause of increased UCR in infected dogs. The other authors suggested hyperureagenesis and myocardial injury as a potential reason for the increased UCR in canine babesiosis. Thus, further studies are needed to determine causes of increased UCR in dogs with babesiosis, especially on the connection between UCR changes and the concentrations of plasma cardiac troponins and ammonia, and the occurrence of occult blood on fecal examination.