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Cytokines and costimulatory molecules: positive and negative regulation of the immune response to Cryptococcus neoformans

100%

Vecchiarelli A.

Archivum Immunologiae et Therapiae Experimentalis

2000

tom 48

nr 6 Spec.Iss.

Monocytes in children with leukemias and lymphomas - down-regulation of HLA and costimulatory molecules

100%

Luczynski W. , Stasiak-Barmuta A. , Krawczuk-Rybak M. , Szymanski M. , Malinowska I. , Mitura-Lesiuk M.

Acta Biochimica Polonica

2004

tom 51

nr 4

The aim of the study was to evaluate the function of monocytes in children with leukemias and lymphomas based on the expression of critical costimulatory, activatory and adhesion molecules (CD80, CD86, HLA-DR and CD54 = ICAM-1), estimated with tricolor flow cytometry. In comparison to the control group we found a lower percentage of monocytes with costimulatory molecules (CD80 before and CD86 after lipopolysaccharide stimulation) at the time of diagnosis and of monocytes with HLA-DR molecules after remission induction. We also noted a lower percentage of monocytes with HLA-DR expression in the group with severe or therapy resistant infections. The results of our investigation suggest some defect in costimulation and antigen presentation in lymphoproliferative diseases in children.

Down-regulation of macrophage immune activity by natural CD8plus regulatory T cells

84%

Bryniarski K. , Szczepanik M. , Ptak M. , Sikora E. , Majewska-Szczepanik M. , Ptak W.

Folia Biologica

2013

tom 61

nr 1-2

Is it wise to target the late cistimulatory molecule OX40 as a therapeutic target?

84%

Cavanagh M. M. , Hussell T.

Archivum Immunologiae et Therapiae Experimentalis

2008

tom 56

nr 5

Angiotensin-(1-7) receptor Mas agonist ameliorates progress of atherosclerosis in apoE-knockout mice

67%

Jawien J. , Toton-Zuranska J. , Gajda M. , Niepsuj A. , Gebska A. , Kus K. , Suski M. , Pyka-Fosciak G. , Nowak B. , Guzik T. J. , Marcinkiewicz J. , Olszanecki R. , Korbut R.

2012

tom 63

nr 1