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NEUROPSYCHOLOGICAL CHARACTERISTIC OF COGNITIVE DISORDERS IN PATIENT WITH CLIPPERS SYNDROME

100%

Peda B. , Kotlęga D. , Masztalewicz M. , Nowacki P.

tom 18(3)

393-401

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a novel inflammatory central nervous system disorder. The diagnosis is made on the basis of the radiological, neurological, neuro - pathological data and responsiveness to steroids treatment. The aim of this paper is to present a neuropsychological characteristic of cognitive, executive and linguistic symptoms characteristic for patient with CLIPPERS disease. In this paper we present the case of a 42-year-old woman with hyperintense punctate foci in the pons, cerebellum, mid- brain, thalamus, white matter of occipital lobes, with a short- term verbal memory deficits, mild deficiency in verbal and pro cedural learning, executive dysfunctions, hand-eye co ordi - nation impairment, psychomotor speed disabilities and dysarthria, associated with a chronic lymphocytic inflammation. In this challenging diagnosis of CLIPPERS, neuropsychological analysis of cognitive functions can be important to optimize the diagnosis and treatment.

Current aspects in postoperative cognitive dysfunctions, including otolaryngological procedures

88%

Rogowska A. , Wygnał N. , Simonienko K. , Kwiatkowski M. , Kuryga D.

nr 2

193-199

Area disorders typically affect executive function, memory, attention, and verbal processing. Factors known to influence postoperative cognitive impairment are: age, preoperative cognitive functioning, and type of anesthesia. Current research into POCD is focused on cardiac and gastric surgery. A rapidly developing surgical technique is endoscopic surgery; specifically, endoscopic transnasal surgery, where a “dry” operating field is required. To date there is little research assessing the impact of this type of surgery on the development. POCD. In the current study we determine the possibility of occurrence of POCD, and investigate its prevention, in the aforementioned surgical situation. General ways to show existing research on POCD in the context of skull base surgery. Hypothetically, less tissue injury is associated with less inflammatory reaction and thus with the reduction of cognitive dysfunctions. Analysis of operating methods (such as derating RR and HR) and their potential impact on POCD. POCD is a temporary postoperative disorder and correlates with poor recovery after surgery. The causes of POCD are multifactorial; however, the immune response following surgery may be the initial factor to initiate the damage-causing ischemic response. Careful anesthesiological and surgical procedures lower the likelihood of POCD.

Developmental disorders in epileptic children

88%

Siegieda-Kozłowska M.

tom 45 EN

85-96

In cases of developmental age epilepsy, development disorders may increase as symptoms, on the one hand, of progressing biological changes, negative psychosocial factors and unintended effects of pharmacological treatment, thus, resulting in neuro-disintegration. The assessment of the motor, cognitive and communication skills of a child with epilepsy enables determination of the kind and range of disorders, the dynamics of motor and cognitive processes.

Functioning of Lexical Connections in Patients with Neurodegenerative Diseases. Case Study of a Patient with Spinocerebellar Ataxia (SCA)

63%

Gatkowska I. , Jauer-Niworowska O.

nr 19

65-84

Aim of the research: interdisciplinary description of functioning of lexical connections in a patient with spinocerebellar ataxia (SCA-type1). There is little research on lexical networks in patients with neurodegenerative diseases. Procedure: the subject was asked to give associations to 63 stimuli-lexemes. Tools used in the study: the Experimental lexical network of the Polish language, a digital recorder, an Olympus 650 DM. The Experimental lexical network was developed by Izabela Gatkowska (2017). It was created as a result of the study concerning the associations of 900 healthy Polish-speaking adults. Utterances of the subject were recorded, transcribed and compared with standard data. Results: the reactions of the subject were different from the associations presented in the Experimental lexical network. The most common verbal reactions were: creating definitions of stimuli-word meanings or making comment on them. Associations created by the subject were based on paradigmatic or syntagmatic relations. The authors explain how the specific verbal behaviour of the subject is related to the cognitive and language dysfunctions caused by the cerebellar damages. The results showed that language processing should not be regarded as separate from other cognitive functions. Verbal reactions of the subject are slightly similar to aphasic symptoms, but mostly they are related to cerebellar damage and executive disorders. The results obtained proved the validity of the connection between linguistic and psychological methods and tools in studies which concern the language behaviour of patients with neurodegenerative diseases.