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PL
Cynamon to powszechnie stosowana przyprawa otrzymywana z kory cynamonowca. Od tysięcy lat jest wykorzystywany w indyjskiej ajurwedzie i tradycyjnej medycynie chińskiej w leczeniu wielu dolegliwości, np. impotencji, trądziku, bólów menstruacyjnych, bólu zębów, duszności, reumatyzmu i infekcji dróg moczowych. Cynamon jest dodawany do wielu produktów: czekolad, alkoholi, napojów, deserów, cukierków, kompotów, wyrobów piekarskich. Amerykańska Agencja ds. Żywności i Leków (FDA) nadała temu surowcowi status GRAS, czyli żywności powszechnie uznanej za bezpieczną. Wyniki wielu badań potwierdzają jego działanie hipoglikemiczne, hipolipemiczne, hipotensyjne, przeciwdrobnoustrojowe. Ponadto cynamon charakteryzuje się wysokim potencjałem przeciwutleniającym.
EN
Cinnamon is commonly used spice obtained from cinnamon bark. For thousands of years cinnamon had been used in Ayurveda and traditional Chinese medicine in the treatment of many diseases e.g.: impotence, acne, menstrual pain, toothache, dyspnea, rheumatism and urinary tract infections. Cinnamon is added to many products: chocolate, alcohol, beverages, desserts, candies, compotes, bakery products. Cinnamon has been granted GRAS status by the US Food and Drug Administration. The results confirm that cinnamon has hypoglycemic, lipid lowering, antihypertensive, anti-microbial properties. Moreover cinnamon possesses a high antioxidant potential.
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nr 1
EN
Two trials were conducted to investigate the effect of a combination of essential oils (CEO) along with fumarate on in vitro rumen fermentation. In trial 1, the essential oil (EO) from thyme, oregano, cinnamon and lemon were mixed at five different ratios. The CEO were applied at levels of 0-500 mg/l. Addition of CEO decreased gas, methane, total volatile fatty acid (VFA) production at 24 h incubation in a dose-dependent manner. Methane tended to decrease much more than total VFA and gas at the same EO level. The mixture of oils at an equal ratio at 500 mg/l that decreased methane much more than VFA was chosen as the optimal combination. In trial 2, the optimal combination was used with 0, 5, 10 or 15 mmol/l of monosodium fumarate. Addition of fumarate further decreased methane production, with 10 mmol/l fumarate resulting in the largest reduction (80.2%) and the smallest decrease in total VFA (5.7%) and gas production (16.7%). Quantification of several ruminal microbe populations by RT-PCR showed that the optimal combination sharply decreased ruminal protozoa; the populations of fungi and fibrolytic bacteria were also decreased. In summary, at an appropriate level, CEO can inhibit methane production. Inclusion of fumarate can further decrease it, which is attributed mainly to inhibition of protozoa and methanogens.
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nr 3
543-552
EN
Thymol and cinnamaldehyde, extracted from thyme and cinnamon respectively, have multiple effects on mammalian cells. Although the intestinal mucosa is one of the first tissues they are in contact with when ingested, their effect on intestinal epithelial cells and especially ion secretion has not been established yet. The aim of this study was to investigate the effect of those two substances on electrolyte secretion and absorption across the porcine jejunal epithelium in Ussing chambers. Jejunal tissues from piglets were mounted in Ussing chambers and the short circuit current measured (Isc) after addition of thymol or cinnamaldehyde. Thymol and cinnamaldehyde induced a dose-dependent increase is Isc. The effect of thymol was inhibited in low Cl-, HCO3- free or low Cl-/ HCO3- free buffers. It was completely blocked when tissues were previously incubated with tetrodotxin and partially inhibited with hexamethonium. Cinnamaldehyde effect was inhibited when HCO3- free or low Cl-/ HCO3- free buffers were used. It was not affected by tetrodotoxin but reduced by hexamethonium, suggesting direct activation of receptors on epithelial cells. In conclusion, thymol induces Cl- and HCO3- secretion via activation of nervous nicotinic receptors while cinnamaldehyde induces HCO3- secretion probably via direct activation of nicotinic receptors on epithelial cells.
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