Wyniki wyszukiwania - Biblioteka Nauki

1

Carotid access in Transcatheter Aortic Valve Implantation – an alternative to the gold standard. A single-center experience

100%

Stańska A. , Wierzbowska A. , Targoński R. , Karolak W. , Mickiewicz A. , Jaguszewski M. , Jagielak D.

European Journal of Translational and Clinical Medicine

|

2019

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tom 2

|

nr 2

80-84

EN

Background: Transfemoral access is regarded as the TAVI gold standard for the transcatheter aortic valve implantation (TAVI) procedure. However, other options for vascular access have developed in the last few years. Access via the carotid artery is one such alternative. Materials and methods: The study included 9 elderly patients who underwent transcarotid TAVI procedure at the Cardiac and Vascular Surgery Department of the Medical University of Gdańsk. Procedures were performed by a local Heart Team in a hybrid operating room under general anesthesia. Data was collected before the implantation and at discharge. Results: The mean patients’ age was 81 years of age (64-88) and the mean logistic EuroSCORE was 10.8 (7-16). Implantations were performed with 100% device success rate. Intra-operative valve-in-valve procedure was performed in one patient; there were no access-related and valve-related complications during the surgery. Post-procedural complications included minor bleeding, hematoma and pneumothorax. Echocardiographic parameters were significantly improving after the procedure. The mean hospital stay was 5 days (2-7 days). Conclusions: Transcatheter aortic valve implantation via the carotid artery appears to be safe and effective alternative to standard TAVI vascular access.

2

Hemodynamic impact of snoring on carotid artery after stent implantation: the role of oscillation

100%

Zhang X. , Fan Z. , Liu X. , Liu M. , Ye X. , Deng X.

Acta of Bioengineering and Biomechanics

|

2023

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tom Vol. 25, no. 1

35--45

EN

Snoring is common in overweight and elderly patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. The results found that high amplitude snoring suppressed the disturbed flow at the stented segment while the downstream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Therefore, older adults should receive medical treatment actively after stenting for high-amplitude snoring as soon as possible to avoid potential adverse events.

3

Common carotid wall elasticity and intima-media thickness examinations by means of ultrasound

100%

Powałowski T. , Hilgertner R. , Trawiński Z.

Archives of Acoustics

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2000

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tom Vol. 25, no. 2

205-212

EN

The aim of this study was to examine the relation between the intima-media thickness and the wall elasticity measured simultaneously in the same cross-section of the common carotid artery. A group of 40 persons (19 healthy and 21 with hypertension and/or atherosclerosis) aged 22 to 81 were diagnosed by means of ultrasound. A high correlation occurred between the wall stiffness coefficient [alpha] and the intima-media thickness (r=0.950, p<0.00001)

4

Ultrasonic method for relative changes of intima-media thickness measurements in common carotid artery

100%

Trawiński Z.

|

2008

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tom Vol. 11

411-418

EN

This paper presents results of examinations of the intima-media thickness (IMT) in human common carotid arteries. Ultrasonic examinations were carried out on healthy volunteers with the use of the apparatus Vascular Echo Doppler (VED), designed in IFTR-PAS to measure the elasticity of arteries. Application of the PDA-14 PC-card (Signatec) allowed for the acquisition of ultrasonic RF signal from the output of the apparatus VED and for further analysis of dynamic changes of the IMT during a heart cycle. Changing of the IMT in time as a difference between the instantaneous position of the two tracking slopes of RF echoes was obtained. For this purpose the zero-crossing method, for tracking phase changes of two characteristic rising slopes of the RF ultrasonic echo, was used.

5

Carotid access in Transcatheter Aortic Valve Implantation – an alternative to the gold standard. A single-center experience

100%

Stańska A. , Wierzbowska A. , Targoński R. , Karolak W. , Mickiewicz A. , Jaguszewski M. , Jagielak D.

|

nr 2

80-84

EN

Background: Transfemoral access is regarded as the TAVI gold standard for the transcatheter aortic valve implantation (TAVI) procedure. However, other options for vascular access have developed in the last few years. Access via the carotid artery is one such alternative. Materials and methods: The study included 9 elderly patients who underwent transcarotid TAVI procedure at the Cardiac and Vascular Surgery Department of the Medical University of Gdańsk. Procedures were performed by a local Heart Team in a hybrid operating room under general anesthesia. Data was collected before the implantation and at discharge. Results: The mean patients’ age was 81 years of age (64-88) and the mean logistic EuroSCORE was 10.8 (7-16). Implantations were performed with 100% device success rate. Intra-operative valve-in-valve procedure was performed in one patient; there were no access-related and valve-related complications during the surgery. Post-procedural complications included minor bleeding, hematoma and pneumothorax. Echocardiographic parameters were significantly improving after the procedure. The mean hospital stay was 5 days (2-7 days). Conclusions: Transcatheter aortic valve implantation via the carotid artery appears to be safe and effective alternative to standard TAVI vascular access.

6

Clinical Evaluation of Near-Infrared Cerebral Oximetry in the Awake-Patient Carotid Endarterectomy

88%

Wojciechowski J. , Sidorowicz M. , Szyndler K. , Znaniecki Ł. , Trenkner M. , Halena G. , Brzeziński M. , Rogowski J.

|

2007

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tom 79

|

nr 8

519-525

EN

The aim of the study was to evaluate the usefulness of continuous monitoring of regional cerebral oxygen saturation (rSO2) for detection of brain ischemia during carotid endarterectomy.Material and methods. We performed 44 carotid endarterectomies using regional anesthesia, with simultaneous regional cerebral oxygen saturation monitoring in both hemispheres of the brain.Results. Oxygen saturation in the hemisphere ipsilateral to the operated carotid artery dropped from 65.1±8.1 to 58.2±10.7 after carotid artery cross-clamping. The difference was statistically significant (p<0.005). Oxygen saturation in the hemisphere contralateral to the operated artery did not demonstrate a difference between that before or after carotid artery closure (65.7±9.2 and 66.1±10.2, respectively, p=0.1). In five patients (11.4%) carotid artery clamping was associated with the appearance of neurological deficits. Shunt usage was necessary in four cases; the rSO2 decreased by 19.2±14% in this group. In the group without neurological deficit during carotid clamping, the rSO2 decreased by 9.7±10.3% (the difference between groups with and without neurological deficit was not statistically significant, p=0.5). In patients with a rSO2 drop above 20%, the sensitivity of the cerebral oximetry was 20% and specificity 97.5%, while the negative predictive value was 90.7%.Conclusions. Continuous cerebral oximetry is a simple and non-invasive method of patient monitoring during carotid endarterectomy. The rSO2 decreases significantly after the ICA clamping. The sensitivity of cerebral oximetry in prediction of neurological deficit during the procedure is low. Defining the threshold value of rSO2 decrease after ICA clamping as an indication for shunt was not possible with the results of this study.

7

Intima–media complex thickness and carotid atherosclerotic plaque formation in Lublin’s population in the context of selected comorbidities

88%

Słomka T. , Drelich-Zbroja A. , Jarząbek M. , Szczerbo-Trojanowska M.

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tom 18

|

nr 73

133-139

EN

Introduction: Atherosclerosis (arteriosclerosis) is a chronic arterial disease of the arteries with chronic inflammatory. The pathology of atherosclerosis is complex, and the atherosclerotic process is multi-factorial, not fully understood. Risk factors of atherosclerotic lesions may include: lipid disorders, hypertension or diabetes. One of the diagnostic methods of discovering atherosclerosis covers the assessment of the intima–media complex thickness by Doppler ultrasonography. Aim: The aim of this report was an evaluation of the relationships between intima–media complex thickness in the right and left carotid arteries and the occurrence of atheromatous plaque in the Lublin population with respect to three possible concomitant medical conditions, mentioned above. Material and methods: A group of 121 subjects was included into the study, all of the participants being residential inhabitants of the Lublin Voivodship. All the participating patients were requested to fill in a questionnaire. After that, the patients were submitted to Doppler sonography concentrated on intima–media complex thickness evaluation. The occurrence of atheromatous plaque was also assessed in obtained sonographic images. Results: There were statistically significant differences for the intima–media complex thickness and for the atheromatous plaque according to all of the reported diseases: hypocholesterolaemia, hypertension and diabetes. Conclusions: The present study confirms that there is a relationship between the thickness of the intima–media complex in the right and left carotid arteries as well as the occurrence of the atherosclerotic plaque regarding the coexistence of specific disease entities in the subjects of the Lublin population.

PL

Wstęp: Miażdżyca (arterioskleroza) to przewlekła choroba naczyń tętniczych o podłożu zwyrodnieniowo-zapalnym. Patologia miażdżycy jest złożona, a proces miażdżycowy ma charakter wieloczynnikowy, nie do końca poznany. W inicjowaniu zmian miażdżycowych biorą udział różne czynniki ryzyka, do których zalicza się m.in. zaburzenia gospodarki lipidowej, nadciśnienie tętnicze i cukrzycę. Jedną z metod diagnozowania miażdżycy jest ocena grubości kompleksu intima–media za pomocą ultrasonografii dopplerowskiej. Cel pracy: Celem pracy było zbadanie zależności pomiędzy grubością kompleksu intima–media w prawej i lewej tętnicy szyjnej oraz obecnością blaszki miażdżycowej a występowaniem jednej z trzech wymienionych wyżej jednostek chorobowych w populacji lubelskiej. Materiał i metody: Badaniem objęto losowo 121 osób z populacji lubelskiej. Badanych poproszono o wypełnienie ankiety. W kolejnym kroku badani byli kwalifikowani do ultrasonograficznej oceny grubości kompleksu intima–media. Oceniano także występowanie blaszki miażdżycowej w obrazie ultrasonograficznym. Wyniki: Stwierdzono istotne statystycznie różnice w grubości kompleksu intima–media z uwzględnieniem występowania wskazanych jednostek chorobowych: hipercholesterolemii, nadciśnienia tętniczego i cukrzycy. Stwierdzono również istnienie zależności pomiędzy obecnością blaszki miażdżycowej a występowaniem wskazanych jednostek chorobowych u badanych. Wnioski: Przeprowadzone badania potwierdziły, że istnieją zależności pomiędzy grubością kompleksu intima–media w prawej i lewej tętnicy szyjnej oraz obecnością blaszki miażdżycowej a współwystępowaniem opisywanych jednostek chorobowych u badanych w populacji lubelskiej.

8

Effect of exercise rehabilitation on hemodynamic performance after carotid artery stenting: a numerical study

88%

Liu J. , Fan Z. , Liu X. , Xu X. , Liu M. , Ye X. , Deng X.

Acta of Bioengineering and Biomechanics

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2023

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tom Vol. 25, no. 2

3--13

EN

A high in-stent restenosis rate and thrombosis have compromised clinical benefits after vascular stent placement. Exercise rehabilitation after stenting emerges as a promising and practical therapeutic strategy to improve the clinical performance of this therapy, although it remains controversial. The present study aimed to explore the impact of exercise training on hemodynamic performance after vascular stent implantation. Different 3-dimensional computational models based on the patient-specific carotids were constructed to calculate hemodynamic parameters, including flow velocity, time-averaged wall shear (TAWSS), oscillatory shear index (OSI) and relative residence time (RRT). The results demonstrated that exercise training increased TAWSS but decreased OSI and RRT in some cases after the intervention, and high-intensity exercise further suppressed the adverse blood flow. However, exercise training remarkably reduced TAWSS and elevated OSI and RRT in patients with mild stenosis at upstream of stented segment. Additionally, we discovered that the hemodynamic environment change induced by exercise training was not significant compared to the stent position in some cases. Exercise had a less beneficial impact on the disturbed blood flow after the distal common carotid artery (CCA) stenting. These findings highlighted that exercise-induced hemodynamic changes differ under different conditions. The exercise training for the intervention patients should only be performed after a comprehensive vascular function assessment.

9

A rare variation of the inferior alveolar artery with potential clinical consequences

75%

Khaki A. A. , Tubbs R. S. , Shoja M. M. , Shokouhi G. , Farahani R. M.

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nr 4

345-346

EN

Variations of the inferior alveolar artery are seemingly quite rare, especially with regard to its origin from the maxillary artery. We present an unusual case of an inferior alveolar artery that originated from the external carotid artery. To the best of our knowledge, our case is one of only two reports of the inferior alveolar artery arising from the external carotid artery. The clinician who deals with the mandibular region should be aware of such a variation in the arterial architecture.

10

Comparison of cerebrocortical microvascular effects of different hypoxic-ischemic insults in piglets: a LASER-speckle imaging study

75%

Domoki F. , Zolei-Szenasi D. , Olah O. , Toth-Szuki V. , Nemeth J. , Hopp B. , Bari F. , Smausz T.

Journal of Physiology and Pharmacology

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2014

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tom 65

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nr 4

11

A relationship between serological markers of chronic C. pneumoniae and CMV infection and hsp60 in patients with atherosclerotic carotid stenosis

75%

Rabczyński M. , Fiodorenko-Dumas Ż. , Mastej K. , Dumas I. , Adamiec R. , Paprocka-Borowicz M.

Acta Biochimica Polonica

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2015

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tom 62

|

nr 1

89-95

EN

A number of epidemiological studies conducted over the last decade indicate a relationship between specific pathogen infections and the development of atherosclerosis, although no pathogenetic pathways connecting these two have been determined. Recent reports support the role of heat shock proteins (HSPs) in atherogenesis. The HSPs are also believed to be a link between the infection and the development of atherosclerotic lesions. The aims of study: Immunohistochemical evaluation of carotid artery segments to show the relationship between the presence of heat shock proteins and the serum levels of anti-hsp60 antibodies. An attempt to demonstrate a relationship between an expression of chronic C. pneumoniae and CMV antigens. Material and Methods: The study included 41 patients qualified for carotid artery endarterectomy and 18 healthy volunteers of corresponding age. Levels of anti- hsp60, anti-C. pneumoniae IgA and IgG, anti-CMV IgG antibodies as well as hsCRP were determined. Results: The mean serum levels of anti-hsp60 antibodies were higher in patients with advanced atherosclerosis as compared to healthy volunteers (55.3±64.1 vs 32.8±29.8; p < 0.05). There was a strong correlation between anti-hsp60 antibodies and the expression of hsp60 in carotid arterial wall, as confirmed by immunohistochemical evaluation. The study group showed statistically significant higher levels of hsCRP. Furthermore, statistically significant higher serum levels of anti-C. pneumoniae IgG and IgA as well as anti-CMV IgG antibodies were found in the study group as compared to controls. No correlation was shown between the markers of chronic infection induced by the tested pathogens and serum levels of anti-HSP and hsCRP. Conclusions: Higher protein expression in vascular walls is closely correlated with the level of anti-hsp60. At the same time, no significant relationship between anti-hsp60 antibodies and serological markers of infection was observed, which may only indicate an indirect role of infection in the assessment of breaking the immunological tolerance against autologous HSPs.

12

The caroticobasilar artery in species of order Perissodactyla

75%

Frackowiak H. , Giejdasz K. , Godynicki S.

Folia Morphologica

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1997

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tom 56

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nr 4

13

Investigation of blood flow rheology using second-grade viscoelastic model (Phan-Thien–Tanner) within carotid artery

63%

Ramiar A. , Larimi M. M. , Ranjbar A. A.

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tom Vol. 19, no. 3

27--41

EN

Purpose: Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. The fluid is considered to be non-Newtonian, whose flow is governed by the equation of a second-grade viscoelastic fluid and the effects of viscoelastic on blood flow in carotid artery is investigated. Methods: Pulsatile flow studies were carried out in a 3D model of carotid artery. The governing equations were solved using finite volume C++ based on open source code, OpenFOAM. To describe blood flow, conservation of mass and momentum, a constitutive relation of simplified Phan-Thien–Tanner (sPTT), and appropriate relations were used to explain shear thinning behavior. Results: The first recirculation was observed at t = 0.2 s, in deceleration phase. In the acceleration phase from t = 0.3 s to t = 0.5 s, vortex and recirculation sizes in bulb regions in both ECA and ICA gradually increased. As is observed in the line graphs based on extracted data from ICA, at t = 0.2 s, τyy is the maximum amount of wall shear stress and τxy the minimum one. The maximum shear stress occurred in the inner side of the main branch (inner side of ICA and ECA) because the velocity of blood flow in the inner side of the bulb region was maximum due to the created recirculation zone in the opposite side in this area. Conclusions: The rheology of blood flow and shear stress in various important parts (the area that are in higher rates of WSS such as bifurcation region and the regions after bulb areas in both branches, Line1–4 in Fig. 7) were also analyzed. The investigation of velocity stream line, velocity profile and shear stress in various sections of carotid artery showed that the maximum shear stress occurred in acceleration phase and in the bifurcation region between ECA and ICA which is due to velocity gradients and changes in thinning behavior of blood and increasing strain rate in Newtonian stress part.

14

Transverse subisthmic course of the innominate artery in an adult: detailed anatomy and additional variation

63%

Rusu M. C. , Boscu A. L.

Folia Morphologica

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2010

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tom 69

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nr 4

EN

A rare morphology of an aberrant innominate artery (IA) is reported here, together with additional arterial variation encountered in the respective specimen. The IA originated in the aortic arch on the left side of the trachea, coursed on that side of the trachea to reach the left thyroid lobe, turned in at a right angle to pass anterior to the trachea and immediately inferior and parallel to the thyroid isthmus, and finally it divided inferior to the right thyroid lobe into the right subclavian and common carotid arteries. The right common carotid artery immediately turned at a right angle to ascend in the neck. Thus the terminal branches of the IA had origins in a higher position than is usually expected. This aberrant course of the IA determined a step-like morphology in the sagittal plane of the left common carotid artery. Additional variations were also encountered: (a) a lateralised right external carotid artery with the superior thyroid artery initially coursing over the internal carotid artery; (b) the right vertebral artery coursing over the inferior thyroid artery and entering the transverse process of the fifth cervical vertebra; (c) the left subclavian and vertebral arteries were tortuous. Knowledge of the presence of this IA variant, with a transverse subisthmic segment, appears to be important in various surgical approaches, such as tracheostomies, thyroidectomies, and mediastinoscopies; in addition, the variations of the IA and the vertebral arteries are relevant for lower cervical spine approaches. Nevertheless, the lateralised external carotid artery may lead, if unidentified, to hemorrhagic complications during carotid space approaches. It is important for surgeons to be aware that if an aberrant IA is identified it may not be the only variation in that patient. (Folia Morphol 2010; 69, 4: 261–266)

15

Characteristic of the arteries extending from the ascending aorta in broiler chicken (Gallus gallus domesticus)

63%

Kirkillo-Stacewicz K. , Brudnicki W. , Macherzynska A. , Nowicki W. , Skoczylas B. , Wach J.

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2014

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tom 17

|

nr 3

16

Cephalic arteries in the European beaver Castor fiber

63%

Frackowiak H. , Smielowski J.

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nr 2

EN

Cephalic arteries of 17 European beavers Castor fiber Linnaeus, 1758 were examined. After the common carotid arteries were injected with resin, the heads were biologically macerated. Differences between individual specimens as well as asymmetrical distribution of certain arteries were noted. It was found that in the European beaver the common carotid artery divided into external and internal carotid arteries. The internal carotid artery is well developed in C. fiber, whereas in some other rodents it may be obliterated. The examined beavers had no stapedial arteries.

17

Rare cases of arteries branching directly from aortic arch in the man

63%

Czerwinski F. , Mierzwa A. , Krzanowski K. , Michalska G.

Folia Morphologica

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1993

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tom 52

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nr 4

18

The neuroprotective effect of 2-oxoglutarate in the experimental ischemia of hippocampus

51%

Kovalenko T. N. , Ushakova G. A. , Osadchenko I. , Skibo G. G. , Pierzynowski S. G.

Journal of Physiology and Pharmacology

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2011

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tom 62

|

nr 2

EN

In this study we investigated the potential neuroprotective effect of 2-oxoglutarate (2-OG) on the hippocampus in the transient vessel occlusion ischemia model in the Mongolian gerbil. The morphological and biochemical studies were performed at 7 days after occlusion of carotid arteries. The acute reduction of NeuN-positive neurons in the CA1 pyramidal layer of the hippocampus was accompanied by increased staining intensity for GFAP-positive astrocytes, indicative of glial reaction. The neuron death in the CA1 area coincided with a strong 2.4 fold decrease in the membrane forms of neuronal cell adhesion molecules and elevated levels of astrocyte-specific proteins (soluble GFAP to 2,6 times; filament GFAP to 1,5 times; calcium-binding protein S-100b to 1,6 times). Treatment with 2-oxoglutarate (2.28 g/l drinking water) for between 7 and 21 days attenuated the neuronal death and reactive astrogliosis in this model of experimental ischemia by 20-50%. Our results suggest that 2-OG may prevent the disturbances of neural cells that usually take place during ischemic pathology.

19

Blood pressure-independent hypotrophy of the heart, kidneys and conduit arteries after 7-nitroindazole administration to Wistar rats from the prenatal period to adulthood

51%

Kristek F. , Malekova M. , Ondrias K. , Cacanyiova S.

Journal of Physiology and Pharmacology

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2013

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tom 64

|

nr 1

20

Spermine protects in vivo the antioxidant enzymes in transiently hypoperfused rat brain

51%

Farbiszewski R. , Bielawski K. , Bielawska A. , Sobaniec W.

Acta Neurobiologiae Experimentalis

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1995

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tom 55

|

nr 4