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2 Journal of Physiology and Pharmacology. Supplement

2 2006

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Pharmacology at the Jagiellonian University in Krakow, short review of contribution to global science and cardiovascular research through 400 years of history

100%

Wolkow P. P. , Korbut R.

Journal of Physiology and Pharmacology. Supplement

2006

tom 57

nr 1

119-136

Pharmacology at the Jagiellonian University was taught since the foundation of the University in 1364 under then used names of medical botany and pharmacognosy. The first in Poland Division of Pharmacology and Pharmacognosy was created in 1857. Modern era in the history of pharmacology in Krakow starts in 1929 when Prof. Janusz Supniewski became the Head of the Department. He was the relentless researcher whose scientific interests were as diverse as ranging from anticancer chemotherapeutics, antibiotics, and oral hypoglycemic drugs to lipid-lowering agents. Skills of organic chemistry synthesis were of paramount importance for the scientific achievements. Prof. Supniewski died in 1964, leaving the Department well equipped in instruments. He raised in his laboratory many eminent scientists who later beacame heads of pharmacology departments throughout Poland. In 1964, the Head of the Department of Pharmacology became Prof. Ryszard Gryglewski. Under his leadership the Department focused scientific efforts on various aspects of cardiovascular pharmacology. Prof. Gryglewski established collaborations with many of the best pharmacology researchers in the world, including Sir John Vane, Nobel Prize laureate. Prof. Gryglewski's assistants had ample opportunity to train in these laboratories and to bring these skills back to Krakow. Prof. Gryglewski and his team published many articles in the most prestigious scientific journals. The most important themes included discovery of prostacyclin, role of nitric oxide and of free radicals for vascular biology. Since 2003, when Prof. Gryglewski retired, the Department of Pharmacology has been led by Prof. Ryszard Korbut.

Polish thread in the history of circulatory physiology

84%

Skalski J. H. , Kuch J.

Journal of Physiology and Pharmacology. Supplement

2006

tom 57

nr 1

5-41

A review of the most outstanding achievements in physiology of circulation done by scientists and physicians from Poland and evaluation of their contribution to the world knowledge in this matter is presented in the paper. The authors associate the beginnings of the Polish history of studying heart and its diseases with the brilliant physician from the XIVth century - Thomas of Wrocław, and then in the XVIth century, with the most eminent physician of Polish Renaissance, the expert on pulse, Joseph Struś. The attempts to address the issues related to the circulatory system over historical period of early ages, through baroque and the blooming period in medicine of the XIXth, up to our times, were presented. The memories of the exceptional and the more or less known in the world cardiologic ancestors, associated with Poland, were recalled, such as: Adam.Ch. Thebesius, Robert Remak, Edward Korczyński, Oscar Widmann, Napoleon Cybulski, Joseph Pawiński, Andrew Klisiecki, Adolph Beck, Leon Popielski, Wiesław Hołobut and many others. The analysis of Polish achievements in the field of diagnosing and treatment of the ischaemic heart disease, starting from beginnings of the XIXth century, was performed. The authors also tried to recapitulate the achievements of the last 50 years in cardiological diagnostics, modern interventional cardiology, cardiac surgery along with transplantology and the scientific programmes concerning these issues. The examples of the greatest scientific achievements related to the circulatory system and to myocardial physiology and pathology over the period of recent decade were described.