Wyniki wyszukiwania - Biblioteka Nauki

1

Localization of calcitonin mRNA using in situ labeling with reverse transcriptase and PCR

100%

Zabel M. , Ciesielska U. , Wysocka T.

Folia Histochemica et Cytobiologica. Supplement

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1996

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tom 34

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nr 1

2

Mechanical analysis and numerical simulation of modified bone cements in the hip joint alloplasty

86%

Nowacki J. , Sajek A.

Journal of Achievements in Materials and Manufacturing Engineering

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2011

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tom Vol. 46, nr 1

57--64

EN

Purpose: The paper aims at verifying the stress values in bone-cement-implant system during human movement cycle and determining the amount of bone cement admixture which induces a drop in mechanical properties to acceptable level. Design/methodology/approach: In the first place, mechanical tests of modified cements were carried out. These tests are a basis for mathematical description of mechanical properties which will be used during numerical simulations. Numerical simulations were carried out using the geometry obtained by computer tomography. Findings: A drop in mechanical properties induced by modification depends on admixture size. During movement, cement bond is affected by considerable forces. These forces operate cyclically, i.e. momentarily (when setting a foot on the ground) within the elastic range of examined material. From the point of view of mechanical parameters, an optimum admixture of the aqueous solution of biologically active modifying agent is that inducing porosity at a level of 8%. Research limitations/implications: The paper constitutes a beginning of examinations on modified cement junctures which may be expanded in future by testing the dynamics basing on the analysis of fatigue strength. Practical implications: Modifying agent amount was determined and verified that does not induce a decrease in the bending strength and the longitudinal modulus of elasticity during bending below the level specified in ISO 5833 standard. Originality/value: Modification of cement with aqueous solution of salmon calcitionin, as well as examination and verification of the effect of admixture on mechanical properties.

3

Wpływ wolnozmiennych pól magnetycznych na komórki c tarczycy u samic szczurzych poddanych owariektomii

86%

Bilska A. , Izdebska-Straszak G. , Cieślar G. , Wiczkowski A. , Kubacka M. , Maciaszek-Łój B. , Glinka M. , Sieroń A.

Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna

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2002

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tom Vol. 8, nr 4

169-175

PL

W pracy dokonano oceny wpływu długotrwałej ekspozycji w wolnozmiennym polu magnetycznym na ilość komórek C tarczycy wydzielających kalcytoninę, hormon będący jednym z regulatorów gospodarki wapniowo--fosforanowej u samic szczurzych rasy Wistar po eksperymentalnej owariektomii, stanowiących doświadczalny model osteoporozy pomenopauzalnej. Ekspozycję w wolnozmiennym polu magnetycznym o różnych parametrach fizycznych generowanym przez aparat do magneto terapii Ambit 2000 prowadzono 1 godzinę dziennie przez okres 4 miesięcy. Wykazano znamiennie wyższy (p<0,001) udział komórek C w preparatach tarczycy szczurzyc z grup eksponowanych w polu magnetycznym w porównaniu zarówno ze zwierzętami poddanymi ekspozycji pozorowanej, jak i szczurzycami kontrolnymi nie poddanymi owariektomii. Uzyskane wyniki badań potwierdzają pobudzający efekt wolnozmiennych pól magnetycznych na procesy syntezy komórek C tarczycy produkujących kalcytoninę i tym samym wskazywać mogą pośrednio na udział tego hormonu w mechanizmie osteogenetycznego działania wolnozmiennych pól magnetycznych.

EN

It was estimated the influence of the long-lasting exposure to extremely-low-frequency magnetic fields on the quantity of thyroid C cells secreting calcitonin - hormone acting as one of regulators of calcium-phosphatic metabolism - in ovariectomized Wistar female rats, treated as experimental, animal model of postmenopausal osteoporosis. Significantly higher (p<0,001) percentage of thyroid C cells in thyroid slices of female rats exposed to magnetic fields were observed compared both to sham-exposed animals and control, non-ovariectomized female rats. The results of this study confirm stimulating effect of extremely-low-frequency magnetic fields on thyroid C cells proliferation leading probably to increase in calcitonin synthesis and they indirectly indicate the possible role of this hormone in the mechanism of magnetic field-induced osteogenetic effect.

4

Sensory nerves and calcitonin gene related peptide in the effect of ischemic preconditioning on acute and chronic gastric lesions induced by ischemia-reperfusion

86%

Pawlik M. , Ptak A. , Pajdo R. , Konturek P. C. , Brzozowski T. , Konturek S. J.

Journal of Physiology and Pharmacology

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2001

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tom 52

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nr 4,1

EN

Ischemic preconditioning is considered as the most powerful gastroprotective intervention against mucosal lesions and ulcerations but the mechanism of this phenomenon has been little examined. In this study we tested the effects of inactivation of sensory nerves in new rat model combining acute gastric erosions with subsequent ulcers induced by ischemia-reperfusion (I/R). I/R lesions were produced in rats by clamping the celiac artery for 0.5 h followed by 3 h ofreperfusion in rats with intact or inactivated sensory nerves by pretreatment with capsaicin for two weeks before the I/R. The animals were killed at 0 and 3 h and 3 days after I/R and the area of gastric lesions was determined planimetrically, the gastric blood flow (GBF) by H2-gas clearance technique and the plasma levels of gastrin by RIA. Gastric mucosal content of calcitonin gene related peptide (CGRP) was assessed by RIA. Following I/R, gastric erosive lesions occurred after 3 h and these erosive lesions then progressed into gastric ulcers within 3 days in all rats. Sensory-inactivation with capsaicin caused several fold increase in the area of early (at 3 h) acute lesions and later (at 3 d) gastric ulcers induced by I/R. This enhancement of acute and then chronic gastric lesions was accompanied by a significant fall in GBF, an elevation of plasma gastrin and a decrease in mucosal expression of CGRP. Ischemic preconditioning markedly reduced acute lesions and chronic ulcerations induced by I/R and attenuated the changes in plasma gastrin and mucosal CGRP contents but these effects were significantly more pronounced in rats with intact sensory nerves but less in capsaicin-inactivated animals. We conclude that: 1) The I/R resulted in the formation of early acute gastric lesions followed 3 days later by chronic gastric ulcers and this gastric injury was accompanied by an impairment of gastric microcirculation, hypergastrinemia and suppression the gastric mucosal CGRP; 2) Gastric ischemic-preconditioning significantly attenuated both acute mucosal damage and chronic ulcers induced by I/R and this was accompanied by a rise in gastric blood flow; 3) The inactivation of sensory nerves with capsaicin enhanced the formation of I/R-induced acute and chronic gastric lesions and strongly attenuated the gastroprotection afforded by I/R possibly due to the decline in mucosal blood flow and the fall in expression of integrity peptides such as CGRP and 4) The excessive release of gastrin may limit the extent of mucosal lesions observed during progression of gastric erosions into ulcers induced by I/R.

5

The effects of synthetic salmon calcitonin on thyroid C and follicular cells in adult female rats

86%

Sekulic M. , Sosic-Jurjevic B. , Filipovic B. , Milosevic V. , Nestorovic N. , Monojlovic-Stojanoski M.

Folia Histochemica et Cytobiologica

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2005

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tom 43

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nr 2

6

Immunohistochemistry in detection of paraneoplastic secretion of calcium regulating hormones

72%

Arps H. , Dietel M. , Otto U.

Folia Histochemica et Cytobiologica

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1984

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tom 22

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nr 3-4

7

Calcitonin increases the inhibitory effect of opioid agonist in guinea-pig ileum

72%

Borowicz B. , Sagan M. , Korzeniowska A.

Journal of Physiology and Pharmacology. Supplement

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2001

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tom 52

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nr 2

8

Effect of acute exposure to cadmium on the expression of calcitonin gene-related peptide [CGRP], calcitonin [CT], somatostatin [SST] and synaptophysin [SYN] in the C cells of the rat thyroid - a preliminary study

72%

Czykier E. , Moniuszko-Jakoniuk J. , Sawicki B.

Folia Morphologica

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2004

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tom 63

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nr 2

EN

The aim of the present study was to determine to what degree acute exposure to cadmium affects the expression of CGRP, CT, SST and SYN in the C cells of the rat thyroid. Animals from 7 experimental groups received CdCl₂ iv. in doses of 3.5, 3, 2.5, 2, 1.5, 1 and 0.5 mg/kg b.w. respectively, while the control animals were given 0.9% NaCl iv. 24 hours after the iv. administration of CdCl₂, a correlation was found between a single dose of cadmium and the intensity of the immunocytochemical reactions for CGRP, CT, SST and SYN in C cells of the rat thyroid when compared to the control. The weakest immunocytochemical reactions were noted in C cells of the thyroid of rats from Groups I and II, their intensity gradually increasing in Groups III, IV and V in comparison to the control. The reaction intensity in animals of Groups VI and VII resembled those of the control.

9

Studies on cultured cells of thyroid medullary carcinoma with the use of immunocytochemical techniques

72%

Seidel J. , Zabel M. , Kasprzak A.

Folia Histochemica et Cytobiologica

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1999

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tom 37

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nr 2

10

Immunocytochemical localization of hormones and functional proteins in cultured cells of thyroid medullary carcinoma

72%

Seidel J. , Zabel M. , Kaczmarek A. , Grzeszkowiak J. , Kasprzak A.

Folia Histochemica et Cytobiologica. Supplement

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1996

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tom 34

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nr 1

11

Efficacy of procalcitonin measurement in patients after total thyroidectomy due to medullary thyroid carcinoma

72%

Bolko P. , Manuszewska-Jopek E. , Michalek K. , Wasko R. , Jaskula M. , Sowinski J.

Archivum Immunologiae et Therapiae Experimentalis

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2003

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tom 51

|

nr 6

12

Hybridocytochemical detection of mRNA for calcitonin, CGRP, somatostatin and NPY in cultured cells of medullary thyroid carcinoma using immunomax technique

72%

Kasprzak A. , Zabel M. , Surdyk-Zasada J. , Seidel J.

Folia Histochemica et Cytobiologica

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1999

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tom 37

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nr 2

13

Thyroid C cell function during fasting and refeeding of young and old rats

72%

Kmiec Z. , Kotlarz G. , Mysliwski A. , Wyrzykowska M. , Pokrywka L.

Folia Histochemica et Cytobiologica

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2002

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tom 40

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nr 2

14

Demonstration of calcitonin mRNA in rat thyroid C-cells of the lung: comparison of immunocytochemical and hybridocytochemical results

72%

Kasprzak A. , Seidel J. , Zabel M.

Folia Histochemica et Cytobiologica. Supplement

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1996

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tom 34

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nr 1

15

The effects of selected chemoattractant hormones on mouse sperm acrosome reaction in vitro

72%

Sliwa L.

Acta Biologica Cracoviensia. Series Zoologia

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1998

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tom 40

16

Preliminary immunocytochemical study of C cells of the thyroid and parathyroid glands in five species of wild and laboratory rodents

72%

Sawicki B. , Zabel M.

Folia Histochemica et Cytobiologica

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1999

|

tom 37

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nr 2

17

Control of calcitonin gene expression in thyroid parafollicular cells co-cultured with thyroid follicular cells

72%

Zabel M. , Gebarowska E. , Kasprzak A.

Folia Histochemica et Cytobiologica

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1999

|

tom 37

|

nr 2

18

Morphological and immunohistological characteristics of follicular-compact thyroid carcinoma in dog

58%

Ciaputa R. , Nowak M. , Kandefer-Gola M. , Dziedzic K. , Halupka P. , Pula B. , Kielbowicz M.

Folia Histochemica et Cytobiologica

|

2014

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tom 52

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nr 2

19

Quantitative characteristics of calcitonin-producing cells in the thyroid and lungs of uremic rats

58%

Kasacka I.

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tom 46

|

nr 4

525-530

20

Interaction between the levels of hormones and minerals in sera of healthy and sick cows

58%

Bandzaite V. , Klimiene I. , Spakauskas V. , Matusevicius A.

Polish Journal of Veterinary Sciences

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2005

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tom 08

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nr 4