Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: bupivacain

Sortuj według:

Ogranicz wyniki do:

Intrathecal slow infusion of isobaric bupivacain in low-dose for ovariohysterectomy in dogs

100%

Kacar C. , Ozaydin I. , Oral H. , Kilic E. , Gurbulak K. , Aksoy O.

tom 51

nr 1

The aim of this study was to determine the effects of the catheter-aided intrathecal slow injection of low-dose bupivacain for ovariohysterectomy in 20 non-pregnant dogs. A Tuohy cannula and a spinal catheter were used for infusion. The distance between the lumbosacral-thoracolumbar spaces, was measured under sedation 24 h prior to the operation. The catheter inserted into the subarachnoid region through the lumbosacral space, was advanced into the thoracolumbar space and fixed to the region. One day later, 0.5% bupivacaine was administered via the catheter into the thoracolumbar region at a dose of 1 ml/10 kg and rate of 1 ml/min; afterwards, ovariohysterectomy was performed. Blood pressure, heart rate, respiratory rate, and rectal temperature were recorded prior to anaesthesia, and 10, 20, 30, 45 and 60 min following anaesthesia. Anaesthesia was seen to last for 1.5-3 h. No adverse effects with regard to systolic and diastolic blood pressure, heart and respiratory rates during anaesthesia were observed. With this method, a reliable, fast-acting and desirable anaesthesia was achieved. In conclusion, in cases where general anaesthesia might be dangerous, spinal anaesthesia with a catheter could provide a risk-free option.

Effect of butaphosphane and cyanocobalamin on regeneration of muscle fibres in pigs

72%

Otrocka-Domagala I. , Rotkiewicz T. , Podbielski M. , Wisniewska A. , Drzewiecka A.

nr 3

The aim of the study was to monitor the effect of butaphosphane (1-(n-butylamino)-1-methylophosphorous acid) and cyanocobalamin (Catosal preparation, Bayer AG) on regeneration of the longissimus lumborum muscle (musculus longissimus lumborum) in pigs. Experiments were conducted on 34 piglets of Polish Large White breed with a mean body weight of 20 kg that were divided into two groups. Piglets of group I (control) received an intramuscular injection of 10 cm3 of 0.5% bupivacaine hydrochloride at both side of the spine. Piglets of group II were injected with bupivacaine, as in group I, and additionally received intramuscular injections of 5 ml of Catosal for 5 subsequent days. The animals were euthanized 6, 12, and 24 hours as well as 2, 3, 4, 5, 7, 10 and 14 days after muscle injury. Preparations obtained from muscle specimens were stained with HE, PAS method acc. to McManus, HBFP, Feulgen, and Unna methods. Ultrastructural preparations (TEM) were prepared following a standard procedure. The presence of vimentin, desmin and PCNA was detected immunohistochemically in sections prepared with a paraffin method. Necrosis of muscle fibres was observed in all animals after bupivacaine injection. The administration of Catosal accelerated the regeneration of damaged skeletal muscles in pigs through the facilitation of phagocytosis and enhancement of myogenic cells proliferation. No effect of Catosal was found on differentiation of myoblasts or maturation of newly-formed muscle fibres.