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Zjadliwosc Yersinia enterocolitica oraz znaczenie biotypu 1A w patogenezie jersiniozy

100%

Platt-Samoraj A. , Bancerz-Kisiel A. , Szweda W.

nr 10

1113-1115

Yersinia enterocolitica is an extremely varied organism due to its biochemical, antigen and pathogenic properties. Six biotypes are distinguished within the species but, from the clinical point of view, only five of them: 1B, 2, 3, 4, and 5 are considered to be the cause of yersiniosis. The main criterion for the above division is pathogenicity, which correlates with presence of the virulent pYV plasmid. Microorganisms which lack this plasmid are considered to be a-virulent. However the pYV plasmid may easily be lost during the process of culturing or storage. Biotype 1A strains of Y. enterocolitica are often considered to be non-pathogenic primarily because they do not posses the pYV. These same strains of 1A biotype are able to cause diseases through unknown mechanisms that are independent of the virulent plasmid presence. Evaluating the pathogenicity of this biotype seems to be more complex. The increasing significance of 1A biotype and the possibility of loosing pYV in strains belonging to residual biotypes necessitate further studies which would clear up doubts relating to Y. enterocolitica pathogenicity.