Kadm podawany ciężarnym samicom szczurzym od 7 do 19 dnia ciąży w dawkach 0,2, 2,0 oraz 20,0 mg Cd/kg masy ciała powodował obniżenie aktywności enzymów aktywnego transportu w ścianie dwunastnicy i jelita cienkiego: ATP-azy Mg++ i fosfatazy zasadowej, równolegle aktywując aparat lizosomalny, co wyrażał wzrost odczynu na fosfatazę kwaśną.
EN
60 pregnant female rats divided into three test and one control groups were used in the experiment. Between 7 and 19 day of gestation they were given cadmium by means of stomach tube at daily doses of 0,2, 2,0 and 20,0 mg Cd/kg body weight, depending on the group to which they were assigned. The animals were decapitated on day 21 after gestation. Duodenal and jejunal sections were examined for the activity of Mg++ ATP-ase, alkaline phosphatase (AP), acid phosphatase (AcP), and polysaccharide content by period acid Schiff (PAS); routine hemotoxylin and eosin stainings were also performed. Cadmium lowered active transport enzyme activity in the duodenum and jejunum walls, which was evidenced by lowered reactivity to Mg++ ATP-ase and alkaline phosphatase, while the lysosome apparatus was activated, as manifested by increased acid phosphatase reactivity. Those results seem to confirm that there is no simple dose-effect relationship between cadmium and the functions of the examined enzyme systems.
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.