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EN
Cerebral plasticity plays an important role in learning and in neurological recovery after nervous lesions. However, in certain nervous diseases that same plasticity may lead to nervous system malfunction. Nowadays there are new methods that seem to be able to modulate nervous system function, namely transcranial magnetic stimulation and transcranial direct current stimulation. By use of these methods it may be possible, for example, to transiently improve learning and other mental abilities in normal volunteers or to treat symptoms of maladaptive brain plasticity in various neurological and psychiatric conditions. In this article we review the history, the fundamentals and the most important uses of these techniques.
PL
Przezczaszkowa stymulacja magnetyczna TMS jest techniką pozwalającą na nieinwazyjną, niemal punktową stymulację powierzchownych struktur mózgowia. Tak diagnostyczne, jak i terapeutyczne wykorzystanie techniki TMS wymaga dokładnego umiejscawiania cewki stymulacyjnej nad właściwa okolicą mózgu. Opisano metody mające na celu zwiększenie dokładności stymulacji. Najważniejszą z nich jest neuronawigacja.
EN
Transcranial magnetic stimulation TMS is the technique allowing to non-invasive, almost punctual stimulation of superficial brain structures. Both diagnostic, and therapeutic applying of TMS technique requires accurate putting the stimulation coil over the of the proper brain area. Methods havings on the aim of enlargement of the stimulation accuracy were described. The most important from them is neuronavigation.
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2009
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tom nr 3
CD-CD
PL
W gospodarce opartej na wiedzy szczególną rolę odgrywa szybkość przekazywania informacji niezbędnych do podejmowania decyzji. System zarządzanie transportem (Transportation Management System - TMS) jest komponentem systemu realizacji logistyki (LES). Celem artykułu jest prezentacja obszarów funkcjonalnych i korzyści z zastosowania systemu zarządzania transportem jako rozszerzenia systemu ERP przydatnego w zarządzaniu flotą pojazdów. W artykule krótko opisano system ERP jako narzędzie zarządzania zasobami przedsiębiorstwa oraz rolę transportu w łańcuchu dostaw.
EN
Transportation Management System (TMS) is a part of Logistics Execution System (LES). The aim of the paper is to present the functional areas and advantages of use of transportation management system as an extension of ERP system which can be used in vehicle fleet management. The paper contains the brief description of ERP system as a tool of resource management of enterprise and the role of transportation in the supply chain.
5
Content available remote Neurostimulation, neuromodulation, and the treatment of epilepsies
63%
EN
Introduction. Neurostimulation and neuromodulation are techniques that may be able to affect the course of epilepsy. In the last 20 years, since the approval of VNS, we have observed a surge of studies assessing the potential of other devices and techniques for the treatment of pharmacoresistant epilepsies including deep brain stimulation (DBS), responsive neurostimulation (RNS), trigeminal nerve stimulation (TNS), transcranial direct current stimulation (tDCS), and repetitive transcranial magnetic stimulation (rTMS). Are these devices and techniques simply another treatment option that can be offered to patients with epilepsy or do they offer specific advantages when compared to the standard antiepileptic drugs (AEDs)? Aim. The aim of this review is to present the neurostimulation and neuromodulation devices and techniques that are now in use, or at least available for testing and to discuss the science behind them, their applications, efficacy, potential risks vs. benefits and, above all, how to navigate the choices so clinicians are able to provide their patients with the best possible option for the treatment of epilepsy. Material and methods. We analyzed PubMed and MEDLINE databases to select the most salient and recent (up to November 2014) publications on each treatment device. In addition to these searches bibliographies of selected articles were hand-searched for possible sources. Discussion and conclusions. Great progress in neurostimulation and neuromodulation has been made over the last two decades with 2 devices (VNS, RNS) approved for the treatment of epilepsy in the US and three (DBS in addition to VNS and RNS) in Europe. The future of neuromodulation/neurostimulation is exciting – various studies and efforts are underway and will provide us with more data in the future. There appears to be one clear advantage of these treatments/devices over the AEDs that is consistently noted – routinely observed is continuous improvement in seizure control over time. This is something that the AEDs have thus far failed to deliver.
EN
In the motor system, transcranial magnetic stimulation (TMS) has proved an invaluable tool to study the organisation and interaction of the cortical motor areas. In this review I describe some of the ways in which TMS has been used to map out the major topographical features of the motor output and to test how these change in response motor learning or after peripheral (e.g. amputation) or central (e.g. stroke) injury. More recent work has shown that longer periods of repeated TMS involving several hundred to a thousand pulses can lead to lasting changes in motor cortex excitability that are thought to involve changes in the efficacy of intracortical synapses equivalent to LTP and LTP in slice preparations. These are accompanied by changes in the rate of motor learning and are presently being trialled as potential treatments to speed recovery from stroke.
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