Wyniki wyszukiwania - Biblioteka Nauki

1

The neonatal receptor Fc-gamma (FcRn) ? structure and function

100%

Mikulska J. E.

Postępy Higieny i Medycyny Doświadczalnej

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2001

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tom 55

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nr 4

487-511

EN

The neonatal Fc receptor (FcRn) is named for the source from which it was first purified, the intestinal epithelium of neonatal rats. The human homologue of FcRn was first found in the placenta, where is presumably involved in transfer of maternal IgG to the fetus. FcRn has since been found in capillary endothelium, intestinal epithelium and other tissues. More recent data has indicated that FcRn has a function beyond the transfer of maternal IgG ? the maintenance of constant serum IgG levels. This review summarizes the status of our knowledge on the structure, expression and function of the neonatal Fc? receptor.

2

Dopamine receptors: structure, characterization and functions

100%

Zawilska J. B.

Postępy Higieny i Medycyny Doświadczalnej

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2003

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tom 57

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nr 3

293-322

EN

Dopamine (DA) is an important neurotransmitter/neuromodulator that plays various functions within the body. In the central nervous system, DA is involved in the control of locomotion, cognition, emotion, neuroendocrine secretion and function of retinal cells. In the periphery, DA participates in the regulation of homeostasis, vascular tone and hormone secretion. The diverse physiological functions of DA are mediated by at least five distinct membrane bound receptors, i.e. D1 and D5 -members of D1 family, and D2, D3, D4 ? members of D2 family of DA receptors. All DA receptors belong to the superfamily of G-protein-coupled receptors. This survey summarizes current knowledge on the molecular and pharmacological characterization of DA receptors, their role in the regulation of various processes in an organism, and involvement in the therapy of several disorders, in particular in the treatment of Parkinson?s disease, schizophrenia, and hypertension.

3

Nazwy własne placów targowych w wybranych miastach Polski — swoistość miejsca a model nazewniczy

100%

Górny H.

Onomastica

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2011

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tom 55

93–105

EN

The subject of the article is a description of names of marketplaces in three cities of Poland (Kraków, Warszawa, and Rzeszów) in a historic-comparative formulation. A study of means of nomination and structure of the selected group of proper names in synchronic and diachronic aspect, with consideration of different transportation situations, historical factors, topography, and size of the agglomeration in question, indicates quantitative differences and a somewhat dissimilar repertoire of names in individual centers along with preservation of a similar onymic model. The names of marketplaces reflecting the specificity of a given city are described simultaneously with universalistic tendencies in urbanonymy.

4

MONUMENT BOARD ACTIVITIES AND POLITICAL CONTEXTS (1923-1940) (Politiskie konteksti Piemineklu valdes darbiba (1920-1940)

100%

Petersons R.

Materiali Latvijas makslas vesturei

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2006

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tom 5

93-104

EN

The Monument Board (Piemineklu valde) was a state institution supervised by the Ministry of Education of the Republic of Latvia. Its task was to work on and develop heritage protection. It was founded, taking as a basis the law 'On Monument Protection' passed on 26 January 1923, and functioned until the Soviet occupation in 1940. The structure of the Monument Board changed several times. Part of its members was appointed by the government; part was selected according to the principle of representation from the State Museum of History, the Latvian University and the Latvian Academy of Art. Regardless of the fact that well-known public figures and recognized professionals worked at the Monument Board, the article demonstrates that the heritage protection during the first period of Latvia's independence was dependant on a small group of people and society was not involved in solutions of major issues. Politicians used the Monument Board according to their interests, especially after Karlis Ulmanis established his authoritarian regime in 1934. The question of whether Monument Board members and its director, archaeologist Francis Balodis, were eager to collaborate and serve the regime, subjecting heritage protection issues to the political interests of those in power, remains open.

5

Wielkość i struktura rodziny chłopskiej w parafii rzymskokatolickiej gorzkowskiej w 1791 roku

100%

Rzemieniecki K.

Przeszłość Demograficzna Polski

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2011

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tom 30

79-98

EN

In the late 18th century the Roman Catholic parish of Gorzków was located in the Krasnystaw district, Ruthenian province, south-west of Krasnystaw. It was an ethnically and religiously diverse area, a Polish-Ruthenian and Roman-Greek Catholic borderland. There were neighbourly and family links between the two groups. The article is based on a parish census of 1791. According to the census, the parish comprised the town of Gorzków and 12 villages inhabited by 2420 people, 222 of whom lived in the town. On average, 5.5 lived in a peasant household. This number was influenced by natural population movements as well as spatial mobility of people (servants, landless tenants and adult children leaving their parents’ farms). The most populous households were those headed by 45–49 year-olds. On average, there were 5.8 people living in those households. Most peasant families living in one household in this parish were made up of two generations (77% of families), with very few families being composed of one (13%) or three generations (10%). To use Peter Laslett’s typology, the Gorzków parish was characterised by a high number of nuclear households (73% of the parish), which was markedly different from the situation in the nearby Greek Catholic parishes, where nuclear households accounted for just 41% of the total, with the number of complex families being slightly higher (44%). In the Gorzków parish, complex households made up 8% of the total and extended households — 16%. Single person households and non-family households were rare.

6

THE THEORETIC AND METHODOLOGICAL BASIS FOR THE FORMATION AND DEVELOPMENT OF THE TAX SYSTEM (Teoretyko-metodolohichni zasady formuvannia ta rozvytku podatkovoi systemy)

100%

Fedchak O. M.

Mekhanizm Rehuluvannya Economiky

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2010

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tom 3 (47)

211-218

EN

The article analyzes the theoretical and methodological basis for the formation and development of the tax system, its structure, functions and basic taxation principles of effective taxation. It is considered a scientific approach to the formation and development of the tax system in Ukraine.

7

Components and three-dimensional conformation of basement membrane

100%

Sapilak B. J. , Steciwko A.

Postępy Higieny i Medycyny Doświadczalnej

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2000

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tom 54

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nr 1

83-97

EN

This article presents the latest information about biological functions of basement membranes. It describes all important basement membranes? components and their structure. Schemes showing modular sequence of collagens, nidogen, llaminins and other polypeptides and also structural model of basement membranes were included.

8

Structure and ultrastructure of the egg capsule of Thermobia domestica (Packard) (Insecta, Zygentoma)

100%

Poprawa I. , Rost M. M.

Folia Biologica

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2004

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tom 52

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nr 3-4

185-190

EN

Eggs of Thermobia domestica (Packard) were collected from a laboratory culture. They were prepared for analysis in light and electron microscopes (TEM, SEM). A few hours after oviposition the egg capsule starts to tarnish and changes its colour to brown. Polygonic shapes on its surface can be seen. The egg capsule consists of a thin vitelline envelope and the chorion. The chorion consists of a one-layered endochorion and a three-layered exochorion. There are minor and major mushroom-like structures placed on the surface of the chorion. Their function is proposed. One micropyle is observed on the anterior pole of the egg. The micropylar opening is formed on the process of a follicular cell.

9

The structure of the ribosome-short history

100%

Bakowska-Zywicka K. , Tyczewska A.

Biotechnologia

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2009

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nr 1

99-103

EN

Ribosomes, which are ?the heart of the protein biosynthesis' have been the focus of structural studies for more than 50 years. The reconstitution of some of the morphological features of the ribosome was performed many years ago. In the past few years, high-resolution structures provided molecular details of different intermediates in ribosome-mediated translation. Together, these studies have revolutionized our understanding of the mechanism of protein biosynthesis. This success depended strictly on the advances in biochemical, biophysical and genetic studies and macromolecular crystallography that have been made during last decades.

10

Bacteriocins ? properties and antimicrobial activity

100%

Gwiazdowsk D. , Trojanowska K.

Biotechnologia

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2005

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nr 1

114-130

EN

Bacteriocins are heterogeneous group of ribosomally synthesized proteins or peptides produced by different bacteria that kill or inhibit growth of other bacteria. The interest in bacteriocins results from their potential application as biopreservatives in food to inhibit the growth of spoilage or pathogen bacteria In this paper identification of these metabolites and their physical and biochemical properties, including spectrum of activity, terms of size, amino acid sequence, modes of action and immunity mechanisms are presented.

11

Formuvannia ekoloho-ekonomichnoho mekhanizmu stratehii ekoloho-oriientovanoho rozvytku natsionalnoi ekonomiky

100%

Tur O. M.

Mekhanizm Rehuluvannya Economiky

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2011

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tom 4 (54)

39-43

EN

The theoretical and methodical goings in the forming of the ecology and economy mechanism of forming and realization of strategy of ecologically-pointed development of national economy are offered in the article.

12

Structure and function of T lymphocyte TCR/CD3 complex

100%

Bocko D. , Frydecka I.

Postępy Higieny i Medycyny Doświadczalnej

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2003

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tom 57

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nr 5

519-529

EN

The multichain T cell receptor/CD3 complex (TCR/CD3) plays a key role in antigen recognition, further T cell activation and in consequence in triggering an antigen specific immune response. This process is induced by direct interaction of the TCR receptor with an antigen bound to the major histocompatibile compex on antigen-presenting cells. Upon the structural and functional cooperation of TCR receptor with CD3 complex, the activating signal is transmitted through the cell membrane to the nucleus. The pivotal role in signaling cascade plays CD3-zeta () chain, which triggers many biochemical events and second messenger activation, leading to the transcriptional factors expression and further T cell proliferation, effector function augmentation and cytokine production.

13

NAMES OF OPEN FISHING WATERS OF SELECTED LAKES IN THE DISTRICT OF ELK

100%

Famielec M.

Onomastica

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2003

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tom 48

159-172

EN

The article presents a semantic and structural discussion of 113 names of open fishing waters, selected from four lakes lying within the area of the district of Elk. The toponyms in this article were classified and analyzed according to the model proposed by H. Gornowicz in a work on the names of the Borzechowskie lakes in the Kociewie region. Among the names gathered and presented, the most, 93, are topographic, while the names of 14 are connected with their exploitation, and 7 are commemorative. Structural classification allows to note that compound names predominate among the names of these waters (97). Represented in the greatest numbers are prepositional phrases, with the preposition 'na', very characteristic of directional localizational toponymic names, combined with an allative accusative.

14

NOTCH1 receptor: structure and role during T-cell development

100%

Gidzinska B.

Postępy Higieny i Medycyny Doświadczalnej

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2003

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tom 57

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nr 4

369-376

EN

The Notch family are proteins which function both as cell surface receptors and regulators of gene transcription. Notch proteins influence cell-fate decisions during lymphopoesis, neurogenesis and myogenesis. During lymphopoesis Notch1 is implicated in differentiation of lymphoid precursor CLP towards T-cells but not B-cells lineage. In spite of earlier results suggesting involvement of Notch1 in commitment towards alpha beta and gamm a delta or CD4 and CD8 T cell lineage, later experiments didn?t confirm this possibility.

15

Functions of the HC-Pro proteins encoded by plant viruses from the family Potyviridae

88%

Syller J.

Biotechnologia

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2007

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nr 4

140-156

EN

The helper component-proteinase (HC-Pro) encoded by plant viruses representing the genus Potyvirus (family Potyviridae) is involved in several important viral life processes, including aphid transmission, systemic movement and suppression of post-transcriptional gene silencing. Some of the viruses belonging to the family of the genera Ipomovirus, Rymovirus and Tritimovirus have been demonstrated to produce HC-Pro homologues that are likely to be engaged in vector transmission of these viruses alone. In this paper, the current knowledge of the structure, main functions and molecular mechanisms of the HC-Pro proteins encoded by viruses from the family Potyviridae is presented.

16

Formuvannya konkurentnoyi haluzevoyi struktury pidpryyemstva z vrakhuvannyam kon"yunktury na rynku ahroprodovol'choyi produktsiyi

88%

Danko Y. I.

Mekhanizm Rehuluvannya Economiky

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2016

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tom 2(72)

51-59

EN

The rapid development of domestic agricultural complex causes farms to search tools that provide the improved competitive positions in the market. One of the issues that are constantly under the control of the management of agricultural enterprises is optimizing a branch structure to meet the needs of the consumers. Many works of both domestic and foreign scientists and economists were devoted to peculiarities of sectoral farm structure formation. At the same time, it should be noted that the formation of competitive sectoral structure of the company, taking into account market conditions in terms of agro transitiveness of the economy requires the further scientific research. In this study, we aim to explore the features ensuring the competitiveness of agricultural enterprises through the formation of the optimal branch structure taking into account the market situation of agri-food products. Analyzing the dynamics of changes in the sectoral structure of agricultural enterprises in Ukraine should be noted throughout the period of independence there is a gradual decrease of animal products in total gross output, and the corresponding increase in the sphere of crop production. It is advisable to note that the formation of sectoral structure led to changes in maintenance of management in the agricultural sector. Production of the vast majority of agricultural crops of technical (sunflower, rapeseed) and grain block (corn, barley) concentrated in large agricultural holdings. In such circumstances, smaller farms, trying to ensure its competitiveness forced to find optimal variants of the branch structure with a focus on specific segments according to market conditions of agri-food products. Our studies have shown that there is a logical relationship between the state and trends of fluctuations in the market agri-food products in Ukraine and internal potential of the company. To ensure the competitiveness of the agricultural company, its management must take strategic administrative decisions regarding the construction of optimal branch structure. Thus ensuring the competitiveness of agricultural enterprises is due to the formation of the optimal branch structure taking into account the sales situation in the market of agri-food products.

17

MEDIEVAL NARRATIVE STRUCTURES AND VISUAL TIME (A HISTORIOGRAPHICAL OUTLINE)

88%

Gerát I.

ARS

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2024

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tom 57

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nr 1

3 - 20

EN

For decades, thinking about structures within the Viennese School of Art history has continued without comprehensively embracing and rethinking Wickhoff ’s reflections on pictorial narrative and time. Sedlmayr’s notion of structure was associated with the author’s authoritarian emphasis on abandoning “vulgar time” and achieving a connection with timelessness, which limited his ability to understand the historical formalism established by Riegl. Otto Pächt shifted the focus of his thinking to the problem of visual language and its historical contexts. Creatively developing ideas of Viennese thinkers, Wolfgang Kemp elaborated notion of narrative structures, whose historical anchoring in the analysis of systems of reasoning and representation makes it possible to productively describe the hermeneutic paradoxes associated with developing a visual grammar of pictorial narrative.

18

Structure of the O-polysaccharide of Proteus mirabilis O19 and reclassification of certain Proteus strains that were formerly classified in serogroup O19

88%

Perepelov A. V. , Rozalski A. , Bartodziejska B. , Senchenkova S. N. , Knirel Y. A.

Archivum Immunologiae et Therapiae Experimentalis

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2004

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tom 52

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nr 3

188-196

EN

Bacteria of the genus Proteus are a common cause of urinary tract infections. The O-polysaccharide chain of their LPS (O-antigen) defines the serological specificity of these bacteria. Based on the immunospecificity of the O-antigens, two species, P. mirabilis and P. vulgaris, were classified into 49 O-serogroups, and more O-serogroups for strains of these species and P. penneri have been subsequently proposed. The lipopolysaccharide of P. mirabilis CCUG 19011 from serogroup O19 was degraded and under mildly acidic and mildly alkaline conditions. Polysaccharides thus obtained were studied by chemical methods, including O-deacetylation, sugar and methylation analyses, and 1H- and 13C-NMR spectroscopy. Antisera were obtained by immunization of New Zealand white rabbits with heat-killed bacteria. In serological studies, enzyme immunosorbent assay, passive hemolysis test, and inhibition of passive hemolysis were used.The following structure of the O-polysaccharide repeating unit was established. ->3)-beta-D-GlcpNAc-(1->3)alpha-D-GalpNAc4,6(R-Pyr)-(1->4)-alpha-D-GalpA-(1->3)-alpha-L-Rhap2Ac-(1-> where R-Pyr is (R)-1-carboxyethylidene (an acetal-linked pyruvic acid). This structure is significantly different from the O-polysaccharide structures of P. vulgaris, P. hauseri and P. penneri strains from the same Proteus serogroup O19. Conclusions: Based on immunochemical studies of the lipopolysaccharides, it is suggested 1) to keep P. vulgaris CCUG 4654 and P. penneri 31 in serogroup O19 as two subgroups, 2) to reclassify P. mirabilis CCUG 19011 into a new Proteus serogroup, O51, and 3) to classify serologically related strains, including P. vulgaris ATCC 49990, P. hauseri 1732-80 and 1086-80, P. penneri 15, and some other P. penneri strains, in yet another Proteus serogroup, O52. This structure is significantly different from the O-polysaccharide structures of P. vulgaris, P. hauseri and P. penneri strains from the same Proteus serogroup O19. Based on immunochemical studies of the lipopolysaccharides, it is suggested 1) to keep P. vulgaris CCUG 4654 and P. penneri 31 in serogroup O19 as two subgroups, 2) to reclassify P. mirabilis CCUG 19011 into a new Proteus serogroup, O51, and 3) to classify serologically related strains, including P. vulgaris ATCC 49990, P. hauseri 1732-80 and 1086-80, P. penneri 15, and some other P. penneri strains, in yet another Proteus serogroup, O52.

19

- new AA-derived molecules

88%

Stajszczyk M. , Gaminski J.

Postępy Higieny i Medycyny Doświadczalnej

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1993

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tom 47

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nr 2

133-145

EN

The paper deals with the current state of knowledge on . The , multiple biosynthesis pathways, possible mechanisms of action, and participation of lipoxins in are characterised.

20

Human gastrointestinal tract mucins encoded by the MUC gene family

88%

Paszkiewicz-Gadek A. , Porowska H.

Postępy Higieny i Medycyny Doświadczalnej

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2000

|

tom 54

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nr 2

183-198

EN

Epithelial mucins, MUC gene products, are widely expressed in human organs such as airwais, the urogenital and gastrointestinal tracts, and the eyes. MUC-type mucins have very large sizes and comlex structures with very extensive O-glycosylation and are regarded as protective molecules. The aim of this review is to discuss mucin glycoproteins structure, biosynthesis and functions in normal and pathologicaly altered epithelial mucosa of human gastrointestinal tract.